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  1. Content type: Research

    The tremendous clinical and aetiological diversity among individuals with autism spectrum disorder (ASD) has been a major obstacle to the development of new treatments, as many may only be effective in particu...

    Authors: Eva Loth, Tony Charman, Luke Mason, Julian Tillmann, Emily J. H. Jones, Caroline Wooldridge, Jumana Ahmad, Bonnie Auyeung, Claudia Brogna, Sara Ambrosino, Tobias Banaschewski, Simon Baron-Cohen, Sarah Baumeister, Christian Beckmann, Michael Brammer, Daniel Brandeis…

    Citation: Molecular Autism 2017 8:24

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  2. Content type: Research

    People with fragile X syndrome (FXS) often have deficits in social behavior, and a substantial portion meet criteria for autism spectrum disorder. Though the genetic cause of FXS is known to be due to the sile...

    Authors: Tiffany D. Rogers, Allison M. J. Anacker, Travis M. Kerr, C. Gunnar Forsberg, Jing Wang, Bing Zhang and Jeremy Veenstra-VanderWeele

    Citation: Molecular Autism 2017 8:30

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  3. Content type: Research

    The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism spectrum disorder (ASD). The current paper describes...

    Authors: Tony Charman, Eva Loth, Julian Tillmann, Daisy Crawley, Caroline Wooldridge, David Goyard, Jumana Ahmad, Bonnie Auyeung, Sara Ambrosino, Tobias Banaschewski, Simon Baron-Cohen, Sarah Baumeister, Christian Beckmann, Sven Bölte, Thomas Bourgeron, Carsten Bours…

    Citation: Molecular Autism 2017 8:27

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  4. Content type: Research

    Autism spectrum disorders (ASD) are etiologically heterogeneous and complex. Functional genomics work has begun to identify a diverse array of dysregulated transcriptomic programs (e.g., synaptic, immune, cell...

    Authors: Michael V. Lombardo, Eric Courchesne, Nathan E. Lewis and Tiziano Pramparo

    Citation: Molecular Autism 2017 8:29

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  5. Content type: Research

    A core difficulty for individuals with autism is making friends and successfully engaging and interacting with peers. The majority of measures to assess peer interactions are observations in a school setting o...

    Authors: Rebecca M. Jones, Andrew Pickles and Catherine Lord

    Citation: Molecular Autism 2017 8:28

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  6. Content type: Research

    Autism spectrum disorder (ASD) is a clinically and biologically heterogeneous condition characterized by social, repetitive, and sensory behavioral abnormalities. No treatments are approved for the core diagno...

    Authors: Sameer C. Dhamne, Jill L. Silverman, Chloe E. Super, Stephen H. T. Lammers, Mustafa Q. Hameed, Meera E. Modi, Nycole A. Copping, Michael C. Pride, Daniel G. Smith, Alexander Rotenberg, Jacqueline N. Crawley and Mustafa Sahin

    Citation: Molecular Autism 2017 8:26

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  7. Content type: Research

    The human somatosensory system comprises dissociable paths for discriminative and affective touch, reflected in separate peripheral afferent populations and distinct cortical targets. Differences in behavioral...

    Authors: Michelle D. Failla, Brittany R. Peters, Haleh Karbasforoushan, Jennifer H. Foss-Feig, Kimberly B. Schauder, Brynna H. Heflin and Carissa J. Cascio

    Citation: Molecular Autism 2017 8:25

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  8. Content type: Research

    Despite the fact that deficits in social communication and interaction are at the core of Autism Spectrum Conditions (ASC), no study has yet tested individuals on a continuum from neurotypical development to a...

    Authors: Arianna Curioni, Ilaria Minio-Paluello, Lucia Maria Sacheli, Matteo Candidi and Salvatore Maria Aglioti

    Citation: Molecular Autism 2017 8:23

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  9. Content type: Research

    Studies in the fmr1 KO mouse demonstrate hyper-excitability and increased high-frequency neuronal activity in sensory cortex. These abnormalities may contribute to prominent and distressing sensory hypersensitivi...

    Authors: Lauren E. Ethridge, Stormi P. White, Matthew W. Mosconi, Jun Wang, Ernest V. Pedapati, Craig A. Erickson, Matthew J. Byerly and John A. Sweeney

    Citation: Molecular Autism 2017 8:22

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    The Erratum to this article has been published in Molecular Autism 2017 8:38

  10. Content type: Research

    Autistic individuals commonly show circumscribed or “special” interests: areas of obsessive interest in a specific category. The present study investigated what impact these interests have on attention, an asp...

    Authors: Owen E. Parsons, Andrew P. Bayliss and Anna Remington

    Citation: Molecular Autism 2017 8:20

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  11. Content type: Research

    Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) symptoms and autism spectrum disorder (ASD) symptoms have been reported. Cross-trait genetic relationships are, however, subjec...

    Authors: Evie Stergiakouli, George Davey Smith, Joanna Martin, David H. Skuse, Wolfgang Viechtbauer, Susan M. Ring, Angelica Ronald, David E. Evans, Simon E. Fisher, Anita Thapar and Beate St Pourcain

    Citation: Molecular Autism 2017 8:18

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  12. Content type: Research

    Childhood disintegrative disorder (CDD) is a rare form of autism spectrum disorder (ASD) of unknown etiology. It is characterized by late-onset regression leading to significant intellectual disability (ID) an...

    Authors: Abha R. Gupta, Alexander Westphal, Daniel Y. J. Yang, Catherine A. W. Sullivan, Jeffrey Eilbott, Samir Zaidi, Avery Voos, Brent C. Vander Wyk, Pam Ventola, Zainulabedin Waqar, Thomas V. Fernandez, A. Gulhan Ercan-Sencicek, Michael F. Walker, Murim Choi, Allison Schneider, Tammy Hedderly…

    Citation: Molecular Autism 2017 8:19

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  13. Content type: Research

    Rett syndrome (RTT) is a severe, neurodevelopmental disorder primarily affecting girls, characterized by progressive loss of cognitive, social, and motor skills after a relatively brief period of typical devel...

    Authors: Dejian Zhao, Ryan Mokhtari, Erika Pedrosa, Rayna Birnbaum, Deyou Zheng and Herbert M. Lachman

    Citation: Molecular Autism 2017 8:17

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  14. Content type: Research

    Studies reporting altered susceptibility to visual illusions in autistic individuals compared to that typically developing individuals have been taken to reflect differences in perception (e.g. reduced global ...

    Authors: Catherine Manning, Michael J. Morgan, Craig T. W. Allen and Elizabeth Pellicano

    Citation: Molecular Autism 2017 8:16

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  15. Content type: Research

    Autism spectrum disorder (ASD) is one of the most highly heritable neuropsychiatric disorders, but underlying molecular mechanisms are still unresolved due to extreme locus heterogeneity. Leveraging meaningful...

    Authors: Rui Chen, Lea K. Davis, Stephen Guter, Qiang Wei, Suma Jacob, Melissa H. Potter, Nancy J. Cox, Edwin H. Cook, James S. Sutcliffe and Bingshan Li

    Citation: Molecular Autism 2017 8:14

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  16. Content type: Research

    CHD8 (chromodomain helicase DNA-binding protein 8), which codes for a member of the CHD family of ATP-dependent chromatin-remodeling factors, is one of the most commonly mutated genes ...

    Authors: Ping Wang, Ryan Mokhtari, Erika Pedrosa, Michael Kirschenbaum, Can Bayrak, Deyou Zheng and Herbert M. Lachman

    Citation: Molecular Autism 2017 8:11

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  17. Content type: Review

    According to recent evidence, up to 40–50% of variance in autism spectrum disorder (ASD) liability might be determined by environmental factors. In the present paper, we conducted a review of systematic review...

    Authors: Amirhossein Modabbernia, Eva Velthorst and Abraham Reichenberg

    Citation: Molecular Autism 2017 8:13

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  18. Content type: Research

    Autism spectrum disorder (ASD) is a neurodevelopmental disease characterized by difficulties in social communication, unusually restricted, repetitive behavior and interests, and specific abnormalities in lang...

    Authors: Dominique Endres, Ludger Tebartz van Elst, Simon A. Meyer, Bernd Feige, Kathrin Nickel, Anna Bubl, Andreas Riedel, Dieter Ebert, Thomas Lange, Volkmar Glauche, Monica Biscaldi, Alexandra Philipsen, Simon J. Maier and Evgeniy Perlov

    Citation: Molecular Autism 2017 8:10

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  19. Content type: Research

    Prenatal exposure to infection is a recognized environmental risk factor for neuropsychiatric disorders of developmental origins such as autism or schizophrenia. Experimental work in animals indicates that thi...

    Authors: Stephanie Vuillermot, Wei Luan, Urs Meyer and Darryl Eyles

    Citation: Molecular Autism 2017 8:9

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  20. Content type: Research

    Restricted and repetitive behaviors are defining features of autism spectrum disorder (ASD). Under revised diagnostic criteria for ASD, this behavioral domain now includes atypical responses to sensory stimuli...

    Authors: Jason J. Wolff, Meghan R. Swanson, Jed T. Elison, Guido Gerig, John R. Pruett Jr., Martin A. Styner, Clement Vachet, Kelly N. Botteron, Stephen R. Dager, Annette M. Estes, Heather C. Hazlett, Robert T. Schultz, Mark D. Shen, Lonnie Zwaigenbaum and Joseph Piven

    Citation: Molecular Autism 2017 8:8

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  21. Content type: Research

    Socio-emotional difficulties in autism spectrum disorder (ASD) are thought to reflect impaired functional connectivity within the “social brain”. Nonetheless, a whole-brain characterization of the fast respons...

    Authors: Rocco Mennella, Rachel C. Leung, Margot J. Taylor and Benjamin T. Dunkley

    Citation: Molecular Autism 2017 8:7

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  22. Content type: Research

    The etiology of autism, a complex, heritable, neurodevelopmental disorder, remains largely unexplained. Given the unexplained risk and recent evidence supporting a role for epigenetic mechanisms in the develop...

    Authors: Shannon E. Ellis, Simone Gupta, Anna Moes, Andrew B. West and Dan E. Arking

    Citation: Molecular Autism 2017 8:6

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  23. Content type: Research

    Autism spectrum disorders (ASD) are persistent and lifelong conditions. Despite this, almost all twin studies focus on childhood. This twin study investigated the stability of autistic traits from childhood to...

    Authors: Mark J. Taylor, Christopher Gillberg, Paul Lichtenstein and Sebastian Lundström

    Citation: Molecular Autism 2017 8:5

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  24. Content type: Short Report

    Autism spectrum disorder (ASD) is sexually dimorphic in brain structure, genetics, and behaviors. In studies of brain tissue, the age of the population is clearly a factor in interpreting study outcome, yet se...

    Authors: Cynthia M. Schumann, Frank R. Sharp, Bradley P. Ander and Boryana Stamova

    Citation: Molecular Autism 2017 8:4

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  25. Content type: Research

    Autism spectrum disorder (ASD) affects more than 1% of children in the USA. The male-to-female prevalence ratio of roughly 4:1 in ASD is a well-recognized but poorly understood phenomenon. An explicit focus on...

    Authors: Bo Y. Park, Brian K. Lee, Igor Burstyn, Loni P. Tabb, Jeff A. Keelan, Andrew J. O. Whitehouse, Lisa A. Croen, Margaret D. Fallin, Irva Hertz-Picciotto, Owen Montgomery and Craig J. Newschaffer

    Citation: Molecular Autism 2017 8:3

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  26. Content type: Research

    d-Cycloserine (DCS) enhances extinction learning across species, but it has proven challenging to identify consistent benefit of DCS when added to therapeutic interventions. We conduct...

    Authors: Logan K. Wink, Noha F. Minshawi, Rebecca C. Shaffer, Martin H. Plawecki, David J. Posey, Paul S. Horn, Ryan Adams, Ernest V. Pedapati, Tori L. Schaefer, Christopher J. McDougle, Naomi B. Swiezy and Craig A. Erickson

    Citation: Molecular Autism 2017 8:2

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  27. Content type: Research

    The causes of autism likely involve genetic and environmental factors that influence neurobiological changes and the neurological and behavioral features of the disorder. Immune factors and inflammation are hy...

    Authors: Carlos A. Pardo, Cristan A. Farmer, Audrey Thurm, Fatma M. Shebl, Jorjetta Ilieva, Simran Kalra and Susan Swedo

    Citation: Molecular Autism 2017 8:1

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  28. Content type: Research

    Children with autism spectrum conditions (ASC) have emotion recognition deficits when tested in different expression modalities (face, voice, body). However, these findings usually focus on basic emotions, usi...

    Authors: Shimrit Fridenson-Hayo, Steve Berggren, Amandine Lassalle, Shahar Tal, Delia Pigat, Sven Bölte, Simon Baron-Cohen and Ofer Golan

    Citation: Molecular Autism 2016 7:52

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  29. Content type: Research

    Autism spectrum disorders (ASD) are increasingly prevalent neurodevelopmental disorders that are behaviorally diagnosed in early childhood. Most ASD cases likely arise from a complex mixture of genetic and env...

    Authors: Diane I. Schroeder, Rebecca J. Schmidt, Florence K. Crary-Dooley, Cheryl K. Walker, Sally Ozonoff, Daniel J. Tancredi, Irva Hertz-Picciotto and Janine M. LaSalle

    Citation: Molecular Autism 2016 7:51

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  30. Content type: Research

    Autism is characterised by atypical social-communicative behaviour and restricted range of interests and repetitive behaviours. These features exist in a continuum in the general population. Behavioural measur...

    Authors: Alokananda Rudra, Jai Ranjan Ram, Tom Loucas, Matthew K. Belmonte and Bhismadev Chakrabarti

    Citation: Molecular Autism 2016 7:50

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  31. Content type: Research

    Autism spectrum disorders (ASD) are complex conditions whose pathogenesis may be attributed to gene–environment interactions. There are no definitive mechanisms explaining how environmental triggers can lead t...

    Authors: Maria Fiorentino, Anna Sapone, Stefania Senger, Stephanie S. Camhi, Sarah M. Kadzielski, Timothy M. Buie, Deanna L. Kelly, Nicola Cascella and Alessio Fasano

    Citation: Molecular Autism 2016 7:49

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  32. Content type: Research

    Autism spectrum conditions (ASC) are frequently associated with motor coordination difficulties. However, no studies have explored the prevalence of dyspraxia in a large sample of individuals with and without ...

    Authors: Sarah Cassidy, Penelope Hannant, Teresa Tavassoli, Carrie Allison, Paula Smith and Simon Baron-Cohen

    Citation: Molecular Autism 2016 7:48

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  33. Content type: Research

    Autism spectrum disorder (ASD) is still diagnosed through behavioral observation, due to a lack of laboratory biomarkers, which could greatly aid clinicians in providing earlier and more reliable diagnoses. Me...

    Authors: Federica Gevi, Lello Zolla, Stefano Gabriele and Antonio M. Persico

    Citation: Molecular Autism 2016 7:47

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  34. Content type: Research

    A prominent diagnostic criterion of autism spectrum disorder (ASD) relates to the abnormal or diminished use of facial expressions. Yet little is known about the mechanisms that contribute to this feature of ASD.

    Authors: Dominic A. Trevisan, Marleis Bowering and Elina Birmingham

    Citation: Molecular Autism 2016 7:46

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  35. Content type: Short report

    Mimetic desire (MD), the spontaneous propensity to pursue goals that others pursue, is a case of social influence that is believed to shape preferences. Autism spectrum disorder (ASD) is defined by both atypic...

    Authors: Baudouin Forgeot d’Arc, Fabien Vinckier, Maël Lebreton, Isabelle Soulières, Laurent Mottron and Mathias Pessiglione

    Citation: Molecular Autism 2016 7:45

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  36. Content type: Research

    The search for genetic factors underlying autism spectrum disorders (ASD) has led to the identification of hundreds of genes containing thousands of variants that differ in mode of inheritance, effect size, fr...

    Authors: Eric Larsen, Idan Menashe, Mark N. Ziats, Wayne Pereanu, Alan Packer and Sharmila Banerjee-Basu

    Citation: Molecular Autism 2016 7:44

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  37. Content type: Research

    Fragile X syndrome (FXS), a common cause of intellectual disability and autism, results from the expansion of a CGG-repeat tract in the 5′ untranslated region of the FMR1 gene to >200 repeats. Such expanded allel...

    Authors: Yifan Zhou, Daman Kumari, Nicholas Sciascia and Karen Usdin

    Citation: Molecular Autism 2016 7:42

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  38. Content type: Research

    The insular cortex comprises multiple functionally differentiated sub-regions, each of which has different patterns of connectivity with other brain regions. Such diverse connectivity patterns are thought to u...

    Authors: Takashi Yamada, Takashi Itahashi, Motoaki Nakamura, Hiromi Watanabe, Miho Kuroda, Haruhisa Ohta, Chieko Kanai, Nobumasa Kato and Ryu-ichiro Hashimoto

    Citation: Molecular Autism 2016 7:41

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  39. Content type: Research

    Recent studies have indicated that quantitative autistic traits (QATs) of parents reflect inherited liabilities that may index background genetic risk for clinical autism spectrum disorder (ASD) in their offsp...

    Authors: Joshua Page, John Nicholas Constantino, Katherine Zambrana, Eden Martin, Ilker Tunc, Yi Zhang, Anna Abbacchi and Daniel Messinger

    Citation: Molecular Autism 2016 7:39

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  40. Content type: Research

    Impaired orienting to social stimuli is one of the core early symptoms of autism spectrum disorder (ASD). However, in contrast to faces, name processing has rarely been studied in individuals with ASD. Here, w...

    Authors: Anna Nowicka, Hanna B. Cygan, Paweł Tacikowski, Paweł Ostaszewski and Rafał Kuś

    Citation: Molecular Autism 2016 7:38

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  41. Content type: Short report

    Gastrointestinal dysfunction and gut microbial composition disturbances have been widely reported in autism spectrum disorder (ASD). This study examines whether gut microbiome disturbances are present in the BTBR

    Authors: Christopher Newell, Marc R. Bomhof, Raylene A. Reimer, Dustin S. Hittel, Jong M. Rho and Jane Shearer

    Citation: Molecular Autism 2016 7:37

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  42. Content type: Research

    Atypical lateralization of language-related functions has been repeatedly found in individuals with autism spectrum conditions (ASC). Few studies have, however, investigated deviations from typically occurring...

    Authors: Dorothea L. Floris, Anita D. Barber, Mary Beth Nebel, Mary Martinelli, Meng-Chuan Lai, Deana Crocetti, Simon Baron-Cohen, John Suckling, James J. Pekar and Stewart H. Mostofsky

    Citation: Molecular Autism 2016 7:35

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