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  1. Non-suicidal self-injury (NSSI) has been linked with a higher risk of suicide attempts in autistic and non-autistic people. In the general population, NSSI may confer acquired capability for suicide by eroding...

    Authors: Rachel L. Moseley, Nicola J. Gregory, Paula Smith, Carrie Allison, Sarah Cassidy and Simon Baron-Cohen
    Citation: Molecular Autism 2022 13:45
  2. There has been a growing interest in the association between maternal levels of vitamin D during pregnancy and offspring autism. However, whether any associations reflect causal effects is still inconclusive.

    Authors: Paul Madley-Dowd, Christina Dardani, Robyn E. Wootton, Kyle Dack, Tom Palmer, Rupert Thurston, Alexandra Havdahl, Jean Golding, Deborah Lawlor and Dheeraj Rai
    Citation: Molecular Autism 2022 13:44
  3. Difficulties in social communication are a defining clinical feature of autism. However, the underlying neurobiological heterogeneity has impeded targeted therapies and requires new approaches to identifying c...

    Authors: Hannah Meyer-Lindenberg, Carolin Moessnang, Bethany Oakley, Jumana Ahmad, Luke Mason, Emily J. H. Jones, Hannah L. Hayward, Jennifer Cooke, Daisy Crawley, Rosemary Holt, Julian Tillmann, Tony Charman, Simon Baron-Cohen, Tobias Banaschewski, Christian Beckmann, Heike Tost…
    Citation: Molecular Autism 2022 13:43
  4. Deficits in establishing and maintaining eye-contact are early and persistent vulnerabilities of autism spectrum disorder (ASD), and the neural bases of these deficits remain elusive. A promising hypothesis is...

    Authors: Adam J. Naples, Jennifer H. Foss-Feig, Julie M. Wolf, Vinod H. Srihari and James C. McPartland
    Citation: Molecular Autism 2022 13:42
  5. Across behavioral studies, autistic individuals show greater variability than typically developing individuals. However, it remains unknown to what extent this variability arises from heterogeneity across indi...

    Authors: Umit Keles, Dorit Kliemann, Lisa Byrge, Heini Saarimäki, Lynn K. Paul, Daniel P. Kennedy and Ralph Adolphs
    Citation: Molecular Autism 2022 13:39
  6. Autism spectrum disorder (ASD), like many neurodevelopmental disorders, has complex and varied etiologies. Advances in genome sequencing have identified multiple candidate genes associated with ASD, including ...

    Authors: Josiah D. Zoodsma, Emma J. Keegan, Gabrielle R. Moody, Ashwin A. Bhandiwad, Amalia J. Napoli, Harold A. Burgess, Lonnie P. Wollmuth and Howard I. Sirotkin
    Citation: Molecular Autism 2022 13:38
  7. Puberty is characterized by significant physical, hormonal, and psychological changes, which may be especially challenging for individuals with autism spectrum disorder (ASD). Although the etiology of ASD rema...

    Authors: Rachael A. Muscatello, Emma Rafatjoo, Karan K. Mirpuri, Ahra Kim, Simon Vandekar and Blythe A. Corbett
    Citation: Molecular Autism 2022 13:37
  8. In the last decade, accumulative evidence has shown that oxytocin can modulate social perception in typically developed individuals and individuals diagnosed with autism. While several studies show that oxytoc...

    Authors: Adi Korisky, Ilanit Gordon and Abraham Goldstein
    Citation: Molecular Autism 2022 13:36
  9. Patients with autism spectrum disorder (ASD) experience high rates of sleep disruption beginning early in life; however, the developmental consequences of this disruption are not understood. We examined sleep ...

    Authors: Julia S. Lord, Sean M. Gay, Kathryn M. Harper, Viktoriya D. Nikolova, Kirsten M. Smith, Sheryl S. Moy and Graham H. Diering
    Citation: Molecular Autism 2022 13:35
  10. Mutations in the postsynaptic transmembrane protein neuroligin-3 are highly correlative with autism spectrum disorders (ASDs) and intellectual disabilities (IDs). Fear learning is well studied in models of the...

    Authors: Natasha J. Anstey, Vijayakumar Kapgal, Shashank Tiwari, Thomas C. Watson, Anna K. H. Toft, Owen R. Dando, Felicity H. Inkpen, Paul S. Baxter, Zrinko Kozić, Adam D. Jackson, Xin He, Mohammad Sarfaraz Nawaz, Aiman Kayenaat, Aditi Bhattacharya, David J. A. Wyllie, Sumantra Chattarji…
    Citation: Molecular Autism 2022 13:34
  11. Biological motion imparts rich information related to the movement, actions, intentions and affective state of others, which can provide foundational support for various aspects of social cognition and behavio...

    Authors: Emily J. Knight, Aaron I. Krakowski, Edward G. Freedman, John S. Butler, Sophie Molholm and John J. Foxe
    Citation: Molecular Autism 2022 13:33
  12. Pronounced alexithymia traits have been found in autism spectrum disorder (ASD) and recent research has been carving out the impact alexithymia traits might have on mentalising deficits associated with ASD.

    Authors: Christine M. Falter-Wagner, Carola Bloch, Lana Burghof, Fritz-Georg Lehnhardt and Kai Vogeley
    Citation: Molecular Autism 2022 13:32
  13. Autistic traits are associated with alterations in brain morphology. However, the anatomic location of these differences and their developmental trajectories are unclear. The primary objective of this longitud...

    Authors: Melisa Durkut, Elisabet Blok, Anna Suleri and Tonya White
    Citation: Molecular Autism 2022 13:31
  14. Although the Korean version of the Autism Diagnostic Observation Schedule-2 (K-ADOS‐2) is widely being used to diagnose autism spectrum disorder (ASD) in South Korea, no previous study has examined the validit...

    Authors: So Yoon Kim, Miae Oh, Guiyoung Bong, Da-Yea Song, Nan-He Yoon, Joo Hyun Kim and Hee Jeong Yoo
    Citation: Molecular Autism 2022 13:30
  15. Fragile X syndrome (FXS), the most common genetic cause of autism spectrum disorder and intellectual disability, is caused by the lack of fragile X mental retardation protein (FMRP) expression. FMRP is an mRNA...

    Authors: Magdalena Kalinowska, Mathijs B. van der Lei, Michael Kitiashvili, Maggie Mamcarz, Mauricio M. Oliveira, Francesco Longo and Eric Klann
    Citation: Molecular Autism 2022 13:29
  16. Canonical babbling—producing syllables with a mature consonant, full vowel, and smooth transition—is an important developmental milestone that typically occurs in the first year of life. Some studies indicate ...

    Authors: L. D. Yankowitz, V. Petrulla, S. Plate, B. Tunc, W. Guthrie, S. S. Meera, K. Tena, J. Pandey, M. R. Swanson, J. R. Pruett Jr., M. Cola, A. Russell, N. Marrus, H. C. Hazlett, K. Botteron, J. N. Constantino…
    Citation: Molecular Autism 2022 13:28
  17. Proper cerebral cortical development depends on the tightly orchestrated migration of newly born neurons from the inner ventricular and subventricular zones to the outer cortical plate. Any disturbance in this...

    Authors: Zachary A. Schaaf, Lyvin Tat, Noemi Cannizzaro, Ralph Green, Thomas Rülicke, Simon Hippenmeyer and Konstantinos S. Zarbalis
    Citation: Molecular Autism 2022 13:27
  18. Many empirical studies suggest that higher maternal age increases the likelihood of having an autistic child. However, little is known about factors that may explain this relationship or if higher maternal age...

    Authors: Novika Purnama Sari, Pauline W. Jansen, Laura M. E. Blanken, Amber N. V. Ruigrok, Peter Prinzie, Henning Tiemeier, Simon Baron-Cohen, Marinus H. van IJzendoorn and Tonya White
    Citation: Molecular Autism 2022 13:26
  19. Autism spectrum disorder (ASD) is a common and heterogeneous neurodevelopmental condition that is characterized by the core symptoms of social communication difficulties and restricted and repetitive behaviors...

    Authors: Suma Jacob, Evdokia Anagnostou, Eric Hollander, Roger Jou, Nora McNamara, Linmarie Sikich, Russell Tobe, Declan Murphy, James McCracken, Elizabeth Ashford, Christopher Chatham, Susanne Clinch, Janice Smith, Kevin Sanders, Lorraine Murtagh, Jana Noeldeke…
    Citation: Molecular Autism 2022 13:25
  20. Understanding the development of the neuronal circuitry underlying autism spectrum disorder (ASD) is critical to shed light into its etiology and for the development of treatment options. Resting state EEG pro...

    Authors: Pilar Garcés, Sarah Baumeister, Luke Mason, Christopher H. Chatham, Stefan Holiga, Juergen Dukart, Emily J. H. Jones, Tobias Banaschewski, Simon Baron-Cohen, Sven Bölte, Jan K. Buitelaar, Sarah Durston, Bob Oranje, Antonio M. Persico, Christian F. Beckmann, Thomas Bougeron…
    Citation: Molecular Autism 2022 13:22
  21. Neuroimage literature of autism spectrum disorder (ASD) has a moderate-to-high risk of bias, partially because those combined with intellectual impairment (II) and/or minimally verbal (MV) status are generally...

    Authors: Chun-Hung Yeh, Rung-Yu Tseng, Hsing-Chang Ni, Luca Cocchi, Jung-Chi Chang, Mei-Yun Hsu, En-Nien Tu, Yu-Yu Wu, Tai-Li Chou, Susan Shur-Fen Gau and Hsiang-Yuan Lin
    Citation: Molecular Autism 2022 13:21
  22. Altered neuronal excitation–inhibition (E–I) balance is strongly implicated in ASD. However, it is not known whether the direction and degree of changes in the E–I ratio in individuals with ASD correlates with...

    Authors: Viktoriya O. Manyukhina, Andrey O. Prokofyev, Ilia A. Galuta, Dzerassa E. Goiaeva, Tatiana S. Obukhova, Justin F. Schneiderman, Dmitrii I. Altukhov, Tatiana A. Stroganova and Elena V. Orekhova
    Citation: Molecular Autism 2022 13:20
  23. The zinc finger domain containing transcription factor Myt1l is tightly associated with neuronal identity and is the only transcription factor known that is both neuron-specific and expressed in all neuronal s...

    Authors: Markus Wöhr, Wendy M. Fong, Justyna A. Janas, Moritz Mall, Christian Thome, Madhuri Vangipuram, Lingjun Meng, Thomas C. Südhof and Marius Wernig
    Citation: Molecular Autism 2022 13:19
  24. Social attention differences, expressed through gaze patterns, have been documented in autism spectrum disorder (ASD), with subtle differences also reported among first-degree relatives, suggesting a shared ge...

    Authors: Kritika Nayar, Frederick Shic, Molly Winston and Molly Losh
    Citation: Molecular Autism 2022 13:18
  25. Phelan-McDermid syndrome (PMS) is caused by haploinsufficiency of the SHANK3 gene and is characterized by global developmental delays and autism spectrum disorder (ASD). Based on several converging lines of precl...

    Authors: A. Kolevzon, M. S. Breen, P. M. Siper, D. Halpern, Y. Frank, H. Rieger, J. Weismann, M. P. Trelles, B. Lerman, R. Rapaport and J. D. Buxbaum
    Citation: Molecular Autism 2022 13:17
  26. Eye tracking (ET) is a powerful methodology for studying attentional processes through quantification of eye movements. The precision, usability, and cost-effectiveness of ET render it a promising platform for...

    Authors: Frederick Shic, Adam J. Naples, Erin C. Barney, Shou An Chang, Beibin Li, Takumi McAllister, Minah Kim, Kelsey J. Dommer, Simone Hasselmo, Adham Atyabi, Quan Wang, Gerhard Helleman, April R. Levin, Helen Seow, Raphael Bernier, Katarzyna Charwaska…
    Citation: Molecular Autism 2022 13:15
  27. While there are known risk factors for suicidality in autistic adults, these are often unconnected from theoretical frameworks that might explain why risk is elevated and guide clinical interventions. The present...

    Authors: R. L. Moseley, N. J. Gregory, P. Smith, C. Allison, S. Cassidy and S. Baron-Cohen
    Citation: Molecular Autism 2022 13:14

    The Correction to this article has been published in Molecular Autism 2022 13:16

  28. Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterised by a dyad of behavioural symptoms—social and communication deficits and repetitive behaviours. Multiple aetiological genetic and en...

    Authors: Kevin Lee, Yewon Jung, Yukti Vyas, Imogen Skelton, Wickliffe C. Abraham, Yi-Ping Hsueh and Johanna M. Montgomery
    Citation: Molecular Autism 2022 13:13
  29. Repetitive action, resistance to environmental change and fine motor disruptions are hallmarks of autism spectrum disorder (ASD) and other neurodevelopmental disorders, and vary considerably from individual to...

    Authors: Ugne Klibaite, Mikhail Kislin, Jessica L. Verpeut, Silke Bergeler, Xiaoting Sun, Joshua W. Shaevitz and Samuel S.-H. Wang
    Citation: Molecular Autism 2022 13:12
  30. Although autism spectrum disorder (ASD) is a common developmental disorder, our knowledge about a behavioral and neurobiological female phenotype is still scarce. As the conceptualization and understanding of ...

    Authors: Sanna Stroth, Johannes Tauscher, Nicole Wolff, Charlotte Küpper, Luise Poustka, Stefan Roepke, Veit Roessner, Dominik Heider and Inge Kamp-Becker
    Citation: Molecular Autism 2022 13:11
  31. There is still no approved medication for the core symptoms of autism spectrum disorder (ASD). This network meta-analysis investigated pharmacological and dietary-supplement treatments for ASD.

    Authors: Spyridon Siafis, Oğulcan Çıray, Hui Wu, Johannes Schneider-Thoma, Irene Bighelli, Marc Krause, Alessandro Rodolico, Anna Ceraso, Giacomo Deste, Maximilian Huhn, David Fraguas, Antonia San José Cáceres, Dimitris Mavridis, Tony Charman, Declan G. Murphy, Mara Parellada…
    Citation: Molecular Autism 2022 13:10
  32. Clinical and etiological varieties remain major obstacles to decompose heterogeneity in autism spectrum disorders (ASD). Recently, neuroimaging raised new hope to identify neurosubtypes of ASD for further unde...

    Authors: Guanlu Liu, Liting Shi, Jianfeng Qiu and Weizhao Lu
    Citation: Molecular Autism 2022 13:9
  33. A significant proportion of variation in likelihood of neurodevelopmental conditions (NDCs) has been attributed to nonshared environmental (NSE) factors, although it remains unclear which NSE factors pose spec...

    Authors: Johan Isaksson, Vladislav Ruchkin, Nikolas Aho, Karl Lundin Remnélius, Peter B. Marschik and Sven Bölte
    Citation: Molecular Autism 2022 13:8
  34. Autistic adults, particularly women, are more likely to experience chronic ill health than the general population. Central sensitivity syndromes (CSS) are a group of related conditions that are thought to incl...

    Authors: Sarah Grant, Sam Norton, Ricarda F. Weiland, Anke M. Scheeren, Sander Begeer and Rosa A. Hoekstra
    Citation: Molecular Autism 2022 13:7
  35. Phelan–McDermid syndrome (PMS) is caused by 22q13 deletions including SHANK3 or pathogenic sequence variants in SHANK3 and is among the more common rare genetic findings in autism spectrum disorder (ASD). SHANK3 ...

    Authors: S. Sethuram, T. Levy, J. Foss-Feig, D. Halpern, S. Sandin, P. M. Siper, H. Walker, J. D. Buxbaum, R. Rapaport and A. Kolevzon
    Citation: Molecular Autism 2022 13:6
  36. Autistic individuals frequently experience social communication challenges. Girls are diagnosed with autism less often than boys even when their symptoms are equally severe, which may be due to insufficient un...

    Authors: Meredith Cola, Lisa D. Yankowitz, Kimberly Tena, Alison Russell, Leila Bateman, Azia Knox, Samantha Plate, Laura S. Cubit, Casey J. Zampella, Juhi Pandey, Robert T. Schultz and Julia Parish-Morris
    Citation: Molecular Autism 2022 13:5
  37. Authors: Anouck Amestoy, Etienne Guillaud, Giulia Bucchioni, Tiziana Zalla, Daniel Umbricht, Christopher Chatham, Lorraine Murtagh, Josselin Houenou, Richard Delorme, Myriam Ly-Le Moal, Marion Leboyer, Manuel Bouvard and Jean-René Cazalets
    Citation: Molecular Autism 2022 13:4

    The original article was published in Molecular Autism 2021 12:71

  38. Existing research has demonstrated elevated autistic behaviours in children with neurofibromatosis type 1 (NF1), but the autistic phenotype and its relationship to other neurodevelopmental manifestations of NF...

    Authors: Anita K. Chisholm, Kristina M. Haebich, Natalie A. Pride, Karin S. Walsh, Francesca Lami, Alex Ure, Tiba Maloof, Amanda Brignell, Melissa Rouel, Yael Granader, Alice Maier, Belinda Barton, Hayley Darke, Gabriel Dabscheck, Vicki A. Anderson, Katrina Williams…
    Citation: Molecular Autism 2022 13:3
  39. Autism screening is recommended at 18- and 24-month pediatric well visits. The Modified Checklist for Autism in Toddlers—Revised (M-CHAT-R) authors recommend a follow-up interview (M-CHAT-R/F) when positive. M...

    Authors: Raymond Sturner, Barbara Howard, Paul Bergmann, Shana Attar, Lydia Stewart-Artz, Kerry Bet, Carrie Allison and Simon Baron-Cohen
    Citation: Molecular Autism 2022 13:2
  40. Dravet Syndrome is a severe childhood pharmaco-resistant epileptic disorder mainly caused by mutations in the SCN1A gene, which encodes for the α1 subunit of the type I voltage-gated sodium channel (NaV1.1), that...

    Authors: Stefania Beretta, Laura Gritti, Luisa Ponzoni, Paolo Scalmani, Massimo Mantegazza, Mariaelvina Sala, Chiara Verpelli and Carlo Sala
    Citation: Molecular Autism 2022 13:1
  41. The neurocognitive mechanisms underlying autism spectrum disorder (ASD) remain unclear. Progress has been largely hampered by small sample sizes, variable age ranges and resulting inconsistent findings. There ...

    Authors: L. Mason, F. Shic, T. Falck-Ytter, B. Chakrabarti, T. Charman, E. Loth, J. Tillmann, T. Banaschewski, S. Baron-Cohen, S. Bölte, J. Buitelaar, S. Durston, B. Oranje, A. M. Persico, C. Beckmann, T. Bougeron…
    Citation: Molecular Autism 2021 12:74
  42. Autism is a developmental condition, where symptoms are expected to occur in childhood, but a significant number of individuals are diagnosed with autism for the first time in adulthood. Here, we examine diagn...

    Authors: Eya-Mist Rødgaard, Kristian Jensen, Kamilla Woznica Miskowiak and Laurent Mottron
    Citation: Molecular Autism 2021 12:73
  43. Anxiety is prevalent in autism spectrum disorder (ASD) and can negatively impact physical and mental health. Self-awareness of anxiety signs is a key barrier to success of anxiety interventions for many children.

    Authors: Jenny Nguyen, Robyn E. Cardy, Evdokia Anagnostou, Jessica Brian and Azadeh Kushki
    Citation: Molecular Autism 2021 12:72
  44. Inhibitory control and attention processing atypicalities are implicated in various diseases, including autism spectrum disorders (ASD). These cognitive functions can be tested by using visually guided saccade...

    Authors: Anouck Amestoy, Etienne Guillaud, Giulia Bucchioni, Tiziana Zalla, Daniel Umbricht, Christopher Chatham, Lorraine Murtagh, Josselin Houenou, Richard Delorme, Myriam Ly-Le Moal, Marion Leboyer, Manuel Bouvard and Jean-René Cazalets
    Citation: Molecular Autism 2021 12:71

    The Correction to this article has been published in Molecular Autism 2022 13:4

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