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Research
Excitation/inhibition (E/I) imbalance remains a widely discussed hypothesis in autism spectrum disorders (ASD). The presence of such an imbalance may potentially define a therapeutic target for the treatment o...
Molecular Autism 2017 8:47
Published on: 19 September 2017
Research
Autism spectrum disorder (ASD) is characterized by impairments in social communication and restricted or repetitive behaviors or interests. ASD is now diagnosed in more than one out of 100 children and is bias...
Molecular Autism 2017 8:46
Published on: 17 August 2017
Short report
Although the ability to make optimal decisions under uncertainty is an integral part of everyday life, individuals with autism spectrum disorder (ASD) frequently report that they experience difficulties with t...
Molecular Autism 2017 8:45
Published on: 16 August 2017
Research
Arginine vasopressin has been shown to affect social and emotional behaviors, which is mediated by the arginine vasopressin receptor (AVPR1A). Genetic polymorphisms in the AVPR1A promoter region have been identif...
Molecular Autism 2017 8:44
Published on: 9 August 2017
Research
Methyl-CpG-binding protein-2 (MeCP2) is a critical regulator for neural development. Either loss- or gain-of-function leads to severe neurodevelopmental disorders, such as Rett syndrome (RTT) and autism spectrum ...
Molecular Autism 2017 8:43
Published on: 3 August 2017
Research
Tuberous sclerosis complex (TSC) is a rare monogenic disorder characterized by benign tumors in multiple organs as well as a high prevalence of epilepsy, intellectual disability and autism. TSC is caused by in...
Molecular Autism 2017 8:41
Published on: 1 August 2017
Research
The amygdala controls socioemotional behavior and has consistently been implicated in the etiology of autism spectrum disorder (ASD). Precocious amygdala development is commonly reported in ASD youth with the ...
Molecular Autism 2017 8:42
Published on: 1 August 2017
Research
Working memory (WM) often is impaired in autism spectrum disorder (ASD). Such impairment may underlie core deficits in cognition and social functioning. Transcranial direct current stimulation (tDCS) has been ...
Molecular Autism 2017 8:40
Published on: 28 July 2017
Research
There is a lack of agreement about functional connectivity differences in individuals with autism spectrum disorder (ASD). Studies using absolute strength have found reduced connectivity, while those using rel...
Molecular Autism 2017 8:39
Published on: 26 July 2017
Erratum
Molecular Autism 2017 8:38
Published on: 26 July 2017
The original article was published in Molecular Autism 2017 8:22
Research
The presence of attention-deficit/hyperactive disorder (ADHD) symptoms and impaired attention performance are commonly noted in individuals with autism spectrum disorder (ASD). However, little is known about a...
Molecular Autism 2017 8:37
Published on: 25 July 2017
Research
The distinction between autism and Asperger syndrome has been abandoned in the DSM-5. However, this clinical categorization largely overlaps with the presence or absence of a speech onset delay which is associ...
Molecular Autism 2017 8:35
Published on: 21 July 2017
Short report
Both self-regulation and insistence on sameness (IS) are related to anxiety, which is a common feature of individuals with autism spectrum disorder (ASD). Here, we aimed to characterise the IS-self-regulation-...
Molecular Autism 2017 8:36
Published on: 21 July 2017
Review
Autism spectrum disorder (ASD) is a group of complex neurodevelopmental disorders with diverse clinical manifestations and symptoms. In the last 10 years, there have been significant advances in understanding ...
Molecular Autism 2017 8:34
Published on: 10 July 2017
Research article
MicroRNAs, small non-coding RNAs, are highly expressed in the mammalian brain, and the dysregulation of microRNA levels may be involved in neurodevelopmental disorders such as autism spectrum disorder (ASD). I...
Molecular Autism 2017 8:33
Published on: 28 June 2017
Research
Array comparative genomic hybridization (aCGH) is recommended as a first-tier genetic test for children with autism spectrum disorder (ASD). However, interpretation of results can often be challenging partly d...
Molecular Autism 2017 8:31
Published on: 26 June 2017
Research
Rett syndrome (RTT) is a neurodevelopmental disorder that predominantly affects girls. The majority of RTT cases are caused by de novo mutations in methyl-CpG-binding protein 2 (MECP2), and several mouse model...
Molecular Autism 2017 8:32
Published on: 26 June 2017
Research
The tremendous clinical and aetiological diversity among individuals with autism spectrum disorder (ASD) has been a major obstacle to the development of new treatments, as many may only be effective in particu...
Molecular Autism 2017 8:24
Published on: 23 June 2017
Research
People with fragile X syndrome (FXS) often have deficits in social behavior, and a substantial portion meet criteria for autism spectrum disorder. Though the genetic cause of FXS is known to be due to the sile...
Molecular Autism 2017 8:30
Published on: 23 June 2017
Research
The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism spectrum disorder (ASD). The current paper describes...
Molecular Autism 2017 8:27
Published on: 23 June 2017
Research
Autism spectrum disorders (ASD) are etiologically heterogeneous and complex. Functional genomics work has begun to identify a diverse array of dysregulated transcriptomic programs (e.g., synaptic, immune, cell...
Molecular Autism 2017 8:29
Published on: 21 June 2017
Research
A core difficulty for individuals with autism is making friends and successfully engaging and interacting with peers. The majority of measures to assess peer interactions are observations in a school setting o...
Molecular Autism 2017 8:28
Published on: 17 June 2017
Research
Autism spectrum disorder (ASD) is a clinically and biologically heterogeneous condition characterized by social, repetitive, and sensory behavioral abnormalities. No treatments are approved for the core diagno...
Molecular Autism 2017 8:26
Published on: 15 June 2017
Research
The human somatosensory system comprises dissociable paths for discriminative and affective touch, reflected in separate peripheral afferent populations and distinct cortical targets. Differences in behavioral...
Molecular Autism 2017 8:25
Published on: 13 June 2017
Research
Despite the fact that deficits in social communication and interaction are at the core of Autism Spectrum Conditions (ASC), no study has yet tested individuals on a continuum from neurotypical development to a...
Molecular Autism 2017 8:23
Published on: 9 June 2017
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