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Molecular Autism

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  1. Content type: Research

    Methyl-CpG-binding protein-2 (MeCP2) is a critical regulator for neural development. Either loss- or gain-of-function leads to severe neurodevelopmental disorders, such as Rett syndrome (RTT) and autism spectrum ...

    Authors: Zhu Wen, Tian-Lin Cheng, Gai-zhi Li, Shi-Bang Sun, Shun-Ying Yu, Yi Zhang, Ya-Song Du and Zilong Qiu

    Citation: Molecular Autism 2017 8:43

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  2. Content type: Research

    The amygdala controls socioemotional behavior and has consistently been implicated in the etiology of autism spectrum disorder (ASD). Precocious amygdala development is commonly reported in ASD youth with the ...

    Authors: Catherine E. Barrett, Thomas M. Hennessey, Katelyn M. Gordon, Steve J. Ryan, Morgan L. McNair, Kerry J. Ressler and Donald G. Rainnie

    Citation: Molecular Autism 2017 8:42

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  3. Content type: Research

    Working memory (WM) often is impaired in autism spectrum disorder (ASD). Such impairment may underlie core deficits in cognition and social functioning. Transcranial direct current stimulation (tDCS) has been ...

    Authors: J. Jason van Steenburgh, Mark Varvaris, David J. Schretlen, Tracy D. Vannorsdall and Barry Gordon

    Citation: Molecular Autism 2017 8:40

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  4. Content type: Research

    There is a lack of agreement about functional connectivity differences in individuals with autism spectrum disorder (ASD). Studies using absolute strength have found reduced connectivity, while those using rel...

    Authors: Benjamin E. Yerys, John D. Herrington, Theodore D. Satterthwaite, Lisa Guy, Robert T. Schultz and Danielle S. Bassett

    Citation: Molecular Autism 2017 8:39

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  5. Content type: Research

    The presence of attention-deficit/hyperactive disorder (ADHD) symptoms and impaired attention performance are commonly noted in individuals with autism spectrum disorder (ASD). However, little is known about a...

    Authors: Yi-Ling Chien, Miao-Chun Chou, Yen-Nan Chiu, Wen-Jiun Chou, Yu-Yu Wu, Wen-Che Tsai and Susan Shur-Fen Gau

    Citation: Molecular Autism 2017 8:37

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  6. Content type: Short report

    Both self-regulation and insistence on sameness (IS) are related to anxiety, which is a common feature of individuals with autism spectrum disorder (ASD). Here, we aimed to characterise the IS-self-regulation-...

    Authors: Mirko Uljarević, Amanda L. Richdale, David W. Evans, Ru Ying Cai and Susan R. Leekam

    Citation: Molecular Autism 2017 8:36

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  7. Content type: Review

    Autism spectrum disorder (ASD) is a group of complex neurodevelopmental disorders with diverse clinical manifestations and symptoms. In the last 10 years, there have been significant advances in understanding ...

    Authors: Jamie Reilly, Louise Gallagher, June L. Chen, Geraldine Leader and Sanbing Shen

    Citation: Molecular Autism 2017 8:34

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  8. Content type: Research article

    MicroRNAs, small non-coding RNAs, are highly expressed in the mammalian brain, and the dysregulation of microRNA levels may be involved in neurodevelopmental disorders such as autism spectrum disorder (ASD). I...

    Authors: Yuta Hara, Yukio Ago, Erika Takano, Shigeru Hasebe, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda and Kazuhiro Takuma

    Citation: Molecular Autism 2017 8:33

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  9. Content type: Research

    Array comparative genomic hybridization (aCGH) is recommended as a first-tier genetic test for children with autism spectrum disorder (ASD). However, interpretation of results can often be challenging partly d...

    Authors: Annisa Shui Lam Mak, Annie Ting Gee Chiu, Gordon Ka Chun Leung, Christopher Chun Yu Mak, Yoyo Wing Yiu Chu, Gary Tsz Kin Mok, Wing Fai Tang, Kelvin Yuen Kwong Chan, Mary Hoi Yin Tang, Elizabeth Tak-Kwong Lau Yim, Kin Wai So, Victoria Qinchen Tao, Cheuk Wing Fung, Virginia Chun Nei Wong, Mohammed Uddin, So Lun Lee…

    Citation: Molecular Autism 2017 8:31

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  10. Content type: Research

    Rett syndrome (RTT) is a neurodevelopmental disorder that predominantly affects girls. The majority of RTT cases are caused by de novo mutations in methyl-CpG-binding protein 2 (MECP2), and several mouse model...

    Authors: Rylan Allemang-Grand, Jacob Ellegood, Leigh Spencer Noakes, Julie Ruston, Monica Justice, Brian J. Nieman and Jason P. Lerch

    Citation: Molecular Autism 2017 8:32

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  11. Content type: Research

    The tremendous clinical and aetiological diversity among individuals with autism spectrum disorder (ASD) has been a major obstacle to the development of new treatments, as many may only be effective in particu...

    Authors: Eva Loth, Tony Charman, Luke Mason, Julian Tillmann, Emily J. H. Jones, Caroline Wooldridge, Jumana Ahmad, Bonnie Auyeung, Claudia Brogna, Sara Ambrosino, Tobias Banaschewski, Simon Baron-Cohen, Sarah Baumeister, Christian Beckmann, Michael Brammer, Daniel Brandeis…

    Citation: Molecular Autism 2017 8:24

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  12. Content type: Research

    People with fragile X syndrome (FXS) often have deficits in social behavior, and a substantial portion meet criteria for autism spectrum disorder. Though the genetic cause of FXS is known to be due to the sile...

    Authors: Tiffany D. Rogers, Allison M. J. Anacker, Travis M. Kerr, C. Gunnar Forsberg, Jing Wang, Bing Zhang and Jeremy Veenstra-VanderWeele

    Citation: Molecular Autism 2017 8:30

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  13. Content type: Research

    The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism spectrum disorder (ASD). The current paper describes...

    Authors: Tony Charman, Eva Loth, Julian Tillmann, Daisy Crawley, Caroline Wooldridge, David Goyard, Jumana Ahmad, Bonnie Auyeung, Sara Ambrosino, Tobias Banaschewski, Simon Baron-Cohen, Sarah Baumeister, Christian Beckmann, Sven Bölte, Thomas Bourgeron, Carsten Bours…

    Citation: Molecular Autism 2017 8:27

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  14. Content type: Research

    Autism spectrum disorders (ASD) are etiologically heterogeneous and complex. Functional genomics work has begun to identify a diverse array of dysregulated transcriptomic programs (e.g., synaptic, immune, cell...

    Authors: Michael V. Lombardo, Eric Courchesne, Nathan E. Lewis and Tiziano Pramparo

    Citation: Molecular Autism 2017 8:29

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  15. Content type: Research

    A core difficulty for individuals with autism is making friends and successfully engaging and interacting with peers. The majority of measures to assess peer interactions are observations in a school setting o...

    Authors: Rebecca M. Jones, Andrew Pickles and Catherine Lord

    Citation: Molecular Autism 2017 8:28

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  16. Content type: Research

    Autism spectrum disorder (ASD) is a clinically and biologically heterogeneous condition characterized by social, repetitive, and sensory behavioral abnormalities. No treatments are approved for the core diagno...

    Authors: Sameer C. Dhamne, Jill L. Silverman, Chloe E. Super, Stephen H. T. Lammers, Mustafa Q. Hameed, Meera E. Modi, Nycole A. Copping, Michael C. Pride, Daniel G. Smith, Alexander Rotenberg, Jacqueline N. Crawley and Mustafa Sahin

    Citation: Molecular Autism 2017 8:26

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  17. Content type: Research

    The human somatosensory system comprises dissociable paths for discriminative and affective touch, reflected in separate peripheral afferent populations and distinct cortical targets. Differences in behavioral...

    Authors: Michelle D. Failla, Brittany R. Peters, Haleh Karbasforoushan, Jennifer H. Foss-Feig, Kimberly B. Schauder, Brynna H. Heflin and Carissa J. Cascio

    Citation: Molecular Autism 2017 8:25

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  18. Content type: Research

    Despite the fact that deficits in social communication and interaction are at the core of Autism Spectrum Conditions (ASC), no study has yet tested individuals on a continuum from neurotypical development to a...

    Authors: Arianna Curioni, Ilaria Minio-Paluello, Lucia Maria Sacheli, Matteo Candidi and Salvatore Maria Aglioti

    Citation: Molecular Autism 2017 8:23

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  19. Content type: Research

    Studies in the fmr1 KO mouse demonstrate hyper-excitability and increased high-frequency neuronal activity in sensory cortex. These abnormalities may contribute to prominent and distressing sensory hypersensitivi...

    Authors: Lauren E. Ethridge, Stormi P. White, Matthew W. Mosconi, Jun Wang, Ernest V. Pedapati, Craig A. Erickson, Matthew J. Byerly and John A. Sweeney

    Citation: Molecular Autism 2017 8:22

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    The Erratum to this article has been published in Molecular Autism 2017 8:38

  20. Content type: Research

    Autistic individuals commonly show circumscribed or “special” interests: areas of obsessive interest in a specific category. The present study investigated what impact these interests have on attention, an asp...

    Authors: Owen E. Parsons, Andrew P. Bayliss and Anna Remington

    Citation: Molecular Autism 2017 8:20

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  21. Content type: Research

    Childhood disintegrative disorder (CDD) is a rare form of autism spectrum disorder (ASD) of unknown etiology. It is characterized by late-onset regression leading to significant intellectual disability (ID) an...

    Authors: Abha R. Gupta, Alexander Westphal, Daniel Y. J. Yang, Catherine A. W. Sullivan, Jeffrey Eilbott, Samir Zaidi, Avery Voos, Brent C. Vander Wyk, Pam Ventola, Zainulabedin Waqar, Thomas V. Fernandez, A. Gulhan Ercan-Sencicek, Michael F. Walker, Murim Choi, Allison Schneider, Tammy Hedderly…

    Citation: Molecular Autism 2017 8:19

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