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Research
Studies in the fmr1 KO mouse demonstrate hyper-excitability and increased high-frequency neuronal activity in sensory cortex. These abnormalities may contribute to prominent and distressing sensory hypersensitivi...
Molecular Autism 2017 8:22
Published on: 7 June 2017
The Erratum to this article has been published in Molecular Autism 2017 8:38
Research
Over the past decade genome-wide association studies (GWAS) have been applied to aid in the understanding of the biology of traits. The success of this approach is governed by the underlying effect sizes carri...
Molecular Autism 2017 8:21
Published on: 22 May 2017
Research
Autistic individuals commonly show circumscribed or “special” interests: areas of obsessive interest in a specific category. The present study investigated what impact these interests have on attention, an asp...
Molecular Autism 2017 8:20
Published on: 12 April 2017
Research
Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) symptoms and autism spectrum disorder (ASD) symptoms have been reported. Cross-trait genetic relationships are, however, subjec...
Molecular Autism 2017 8:18
Published on: 4 April 2017
Research
Childhood disintegrative disorder (CDD) is a rare form of autism spectrum disorder (ASD) of unknown etiology. It is characterized by late-onset regression leading to significant intellectual disability (ID) an...
Molecular Autism 2017 8:19
Published on: 4 April 2017
Research
Rett syndrome (RTT) is a severe, neurodevelopmental disorder primarily affecting girls, characterized by progressive loss of cognitive, social, and motor skills after a relatively brief period of typical devel...
Molecular Autism 2017 8:17
Published on: 29 March 2017
Research
Large controversy exists regarding the potential existence and clinical significance of larger brain volumes in toddlers who later develop autism. Assessing this relationship is important for determining the c...
Molecular Autism 2017 8:15
Published on: 23 March 2017
Research
Studies reporting altered susceptibility to visual illusions in autistic individuals compared to that typically developing individuals have been taken to reflect differences in perception (e.g. reduced global ...
Molecular Autism 2017 8:16
Published on: 23 March 2017
Research
Autism spectrum disorder (ASD) is one of the most highly heritable neuropsychiatric disorders, but underlying molecular mechanisms are still unresolved due to extreme locus heterogeneity. Leveraging meaningful...
Molecular Autism 2017 8:14
Published on: 21 March 2017
Research
CHD8 (chromodomain helicase DNA-binding protein 8), which codes for a member of the CHD family of ATP-dependent chromatin-remodeling factors, is one of the most commonly mutated genes ...
Molecular Autism 2017 8:11
Published on: 20 March 2017
Review
According to recent evidence, up to 40–50% of variance in autism spectrum disorder (ASD) liability might be determined by environmental factors. In the present paper, we conducted a review of systematic review...
Molecular Autism 2017 8:13
Published on: 17 March 2017
Research
Despite a suggested link between anorexia nervosa (AN) and autism spectrum disorder (ASD), previous studies have used self-report or diagnostic criteria to assess for ASD in AN populations, rather than direct ...
Molecular Autism 2017 8:12
Published on: 16 March 2017
Research
Autism spectrum disorder (ASD) is a neurodevelopmental disease characterized by difficulties in social communication, unusually restricted, repetitive behavior and interests, and specific abnormalities in lang...
Molecular Autism 2017 8:10
Published on: 7 March 2017
Research
Prenatal exposure to infection is a recognized environmental risk factor for neuropsychiatric disorders of developmental origins such as autism or schizophrenia. Experimental work in animals indicates that thi...
Molecular Autism 2017 8:9
Published on: 7 March 2017
Research
Restricted and repetitive behaviors are defining features of autism spectrum disorder (ASD). Under revised diagnostic criteria for ASD, this behavioral domain now includes atypical responses to sensory stimuli...
Molecular Autism 2017 8:8
Published on: 4 March 2017
Research
Socio-emotional difficulties in autism spectrum disorder (ASD) are thought to reflect impaired functional connectivity within the “social brain”. Nonetheless, a whole-brain characterization of the fast respons...
Molecular Autism 2017 8:7
Published on: 22 February 2017
Research
The etiology of autism, a complex, heritable, neurodevelopmental disorder, remains largely unexplained. Given the unexplained risk and recent evidence supporting a role for epigenetic mechanisms in the develop...
Molecular Autism 2017 8:6
Published on: 17 February 2017
Research
Autism spectrum disorders (ASD) are persistent and lifelong conditions. Despite this, almost all twin studies focus on childhood. This twin study investigated the stability of autistic traits from childhood to...
Molecular Autism 2017 8:5
Published on: 17 February 2017
Short Report
Autism spectrum disorder (ASD) is sexually dimorphic in brain structure, genetics, and behaviors. In studies of brain tissue, the age of the population is clearly a factor in interpreting study outcome, yet se...
Molecular Autism 2017 8:4
Published on: 7 February 2017
Research
Autism spectrum disorder (ASD) affects more than 1% of children in the USA. The male-to-female prevalence ratio of roughly 4:1 in ASD is a well-recognized but poorly understood phenomenon. An explicit focus on...
Molecular Autism 2017 8:3
Published on: 31 January 2017
Research
d-Cycloserine (DCS) enhances extinction learning across species, but it has proven challenging to identify consistent benefit of DCS when added to therapeutic interventions. We conduct...
Molecular Autism 2017 8:2
Published on: 25 January 2017
Research
The causes of autism likely involve genetic and environmental factors that influence neurobiological changes and the neurological and behavioral features of the disorder. Immune factors and inflammation are hy...
Molecular Autism 2017 8:1
Published on: 5 January 2017
Research
Children with autism spectrum conditions (ASC) have emotion recognition deficits when tested in different expression modalities (face, voice, body). However, these findings usually focus on basic emotions, usi...
Molecular Autism 2016 7:52
Published on: 19 December 2016
Research
Autism spectrum disorders (ASD) are increasingly prevalent neurodevelopmental disorders that are behaviorally diagnosed in early childhood. Most ASD cases likely arise from a complex mixture of genetic and env...
Molecular Autism 2016 7:51
Published on: 15 December 2016
Research
Autism is characterised by atypical social-communicative behaviour and restricted range of interests and repetitive behaviours. These features exist in a continuum in the general population. Behavioural measur...
Molecular Autism 2016 7:50
Published on: 3 December 2016
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