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  1. Content type: Research

    Amygdala dysfunction is hypothesized to underlie the social deficits observed in autism spectrum disorders (ASD). However, the neurobiological basis of this hypothesis is underspecified because it is unknown w...

    Authors: Annika Rausch, Wei Zhang, Koen V. Haak, Maarten Mennes, Erno J. Hermans, Erik van Oort, Guido van Wingen, Christian F. Beckmann, Jan K. Buitelaar and Wouter B. Groen

    Citation: Molecular Autism 2016 7:13

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  2. Content type: Research

    The ability to follow gaze is an important prerequisite for joint attention, which is often compromised in children with autism spectrum disorder (ASD). The direction of both the head and eyes provides cues to...

    Authors: Emilia Thorup, Pär Nyström, Gustaf Gredebäck, Sven Bölte and Terje Falck-Ytter

    Citation: Molecular Autism 2016 7:12

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  3. Content type: Research

    Individuals with autism spectrum disorder (ASD) have been characterized by altered cerebral cortical structures; however, the field has yet to identify consistent markers and prior studies have included mostly...

    Authors: Daniel Y.-J. Yang, Danielle Beam, Kevin A. Pelphrey, Sebiha Abdullahi and Roger J. Jou

    Citation: Molecular Autism 2016 7:11

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  4. Content type: Research

    Autism spectrum conditions (autism) are diagnosed more frequently in boys than in girls. Females with autism may have been under-identified due to not only a male-biased understanding of autism but also female...

    Authors: Agnieszka Rynkiewicz, Björn Schuller, Erik Marchi, Stefano Piana, Antonio Camurri, Amandine Lassalle and Simon Baron-Cohen

    Citation: Molecular Autism 2016 7:10

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  5. Content type: Review

    Growing evidence points toward a critical role for early (prenatal) atypical neurodevelopmental processes in the aetiology of autism spectrum condition (ASC). One such process that could impact early neural de...

    Authors: Adam M. H. Young, Bhismadev Chakrabarti, David Roberts, Meng-Chuan Lai, John Suckling and Simon Baron-Cohen

    Citation: Molecular Autism 2016 7:9

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  6. Content type: Research

    Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders thought to have both genetic and environmental causes. It has been hypothesized that exposure...

    Authors: Jonna Maria Eriksson, Sebastian Lundström, Paul Lichtenstein, Susanne Bejerot and Elias Eriksson

    Citation: Molecular Autism 2016 7:8

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  7. Content type: Research

    Children with attention deficit/hyperactivity disorder (ADHD) often present with social difficulties, though the extent to which these clearly overlap with symptoms of autism spectrum disorder (ASD) is not wel...

    Authors: Rebecca Grzadzinski, Catherine Dick, Catherine Lord and Somer Bishop

    Citation: Molecular Autism 2016 7:7

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  8. Content type: Research

    Atypical responsiveness to olfactory stimuli has been reported as the strongest predictor of social impairment in children with autism spectrum disorders (ASD). However, previous laboratory-based sensory psych...

    Authors: Hirokazu Kumazaki, Taro Muramatsu, Takashi X. Fujisawa, Masutomo Miyao, Eri Matsuura, Ken-ichi Okada, Hirotaka Kosaka, Akemi Tomoda and Masaru Mimura

    Citation: Molecular Autism 2016 7:6

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  9. Content type: Research

    Genetic, hormonal, and environmental factors contribute since infancy to sexual dimorphism in regional brain structures of subjects with typical development. However, the neuroanatomical differences between ma...

    Authors: Alessandra Retico, Alessia Giuliano, Raffaella Tancredi, Angela Cosenza, Fabio Apicella, Antonio Narzisi, Laura Biagi, Michela Tosetti, Filippo Muratori and Sara Calderoni

    Citation: Molecular Autism 2016 7:5

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  10. Content type: Research

    As evidenced in the DSM-V, autism spectrum disorders (ASD) are often characterized by atypical sensory behavior (hyper- or hypo-reactivity), but very few studies have evaluated olfactory abilities in individua...

    Authors: Bruno Wicker, Elisabetta Monfardini and Jean-Pierre Royet

    Citation: Molecular Autism 2016 7:4

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  11. Content type: Research

    Dysfunctions in the PI3K/mTOR pathway have gained a lot of attention in autism research. This was initially based on the discovery of several monogenic autism spectrum disorders with mutations or defects in PI...

    Authors: Ashwini C. Poopal, Lindsay M. Schroeder, Paul S. Horn, Gary J. Bassell and Christina Gross

    Citation: Molecular Autism 2016 7:3

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  12. Content type: Research

    Researchers have demonstrated that d-cycloserine (DCS) can enhance the effects of behavioral interventions in adults with anxiety and enhances prosocial behavior in animal models of autism spectrum disorders (ASD...

    Authors: Noha F. Minshawi, Logan K. Wink, Rebecca Shaffer, Martin H. Plawecki, David J. Posey, Hai Liu, Sarah Hurwitz, Christopher J. McDougle, Naomi B. Swiezy and Craig A. Erickson

    Citation: Molecular Autism 2016 7:2

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  13. Content type: Research

    Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders caused by the interaction between genetic vulnerability and environmental factors. MicroRNAs (miRNAs) are key posttranscriptional reg...

    Authors: Lam Son Nguyen, Marylin Lepleux, Mélanie Makhlouf, Christelle Martin, Julien Fregeac, Karine Siquier-Pernet, Anne Philippe, François Feron, Bruno Gepner, Claire Rougeulle, Yann Humeau and Laurence Colleaux

    Citation: Molecular Autism 2016 7:1

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  14. Content type: Research

    Findings of auditory abnormalities in children with autism spectrum disorder (ASD) include delayed superior temporal gyrus auditory responses, pre- and post-stimulus superior temporal gyrus (STG) auditory osci...

    Authors: J. Christopher Edgar, Charles L. Fisk IV, Jeffrey I. Berman, Darina Chudnovskaya, Song Liu, Juhi Pandey, John D. Herrington, Russell G. Port, Robert T. Schultz and Timothy P. L. Roberts

    Citation: Molecular Autism 2015 6:69

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  15. Content type: Research

    Recent research investigating the extreme male brain theory of autism spectrum disorders (ASD) has drawn attention to the possibility that autistic type social difficulties may be associated with high prenatal...

    Authors: Manuela Barona, Radha Kothari, David Skuse and Nadia Micali

    Citation: Molecular Autism 2015 6:68

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  16. Content type: Research

    Fragile X syndrome (FXS) is a neurodevelopmental disorder whose biochemical manifestations involve dysregulation of mGluR5-dependent pathways, which are widely modeled using cultured neurons. In vitro phenotyp...

    Authors: Daria Prilutsky, Alvin T. Kho, Nathan P. Palmer, Asha L. Bhakar, Niklas Smedemark-Margulies, Sek Won Kong, David M. Margulies, Mark F. Bear and Isaac S. Kohane

    Citation: Molecular Autism 2015 6:66

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  17. Content type: Research

    Recent brain imaging findings suggest that there are widely distributed abnormalities affecting the brain connectivity in individuals with autism spectrum disorder (ASD). Using graph theoretical analysis, it i...

    Authors: Ulrika Roine, Timo Roine, Juha Salmi, Taina Nieminen-von Wendt, Pekka Tani, Sami Leppämäki, Pertti Rintahaka, Karen Caeyenberghs, Alexander Leemans and Mikko Sams

    Citation: Molecular Autism 2015 6:65

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  18. Content type: Research

    Autism spectrum disorder (ASD) has been associated with autonomic atypicalities, although the nature of these differences remains largely unknown. Moreover, existing literature suggests large variability in au...

    Authors: Sakeena Panju, Jessica Brian, Annie Dupuis, Evdokia Anagnostou and Azadeh Kushki

    Citation: Molecular Autism 2015 6:64

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  19. Content type: Research

    Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impairment in social communication/interaction and inflexible/repetitive behavior. Several lines of evidence support g...

    Authors: Xin He, Stetson Thacker, Todd Romigh, Qi Yu, Thomas W. Frazier Jr and Charis Eng

    Citation: Molecular Autism 2015 6:63

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    The Erratum to this article has been published in Molecular Autism 2016 7:14

  20. Content type: Research

    Aggression is common in patients with autism spectrum disorders (ASD) along with the core symptoms of impairments in social communication and repetitive behavior. Risperidone, an atypical antipsychotic, is wid...

    Authors: Emma L. Burrows, Liliana Laskaris, Lynn Koyama, Leonid Churilov, Joel C. Bornstein, Elisa L. Hill-Yardin and Anthony J. Hannan

    Citation: Molecular Autism 2015 6:62

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  21. Content type: Research

    Individuals severely affected by autism spectrum disorder (ASD), including those with intellectual disability, expressive language impairment, and/or self-injurious behavior (SIB), are underrepresented in the ...

    Authors: Matthew Siegel, Kahsi A. Smith, Carla Mazefsky, Robin L. Gabriels, Craig Erickson, Desmond Kaplan, Eric M. Morrow, Logan Wink and Susan L. Santangelo

    Citation: Molecular Autism 2015 6:61

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  22. Content type: Research

    The Duchenne and Becker muscular dystrophies (DMD, BMD) show significant comorbid diagnosis for autism, and the genomic sequences encoding the proteins responsible for these diseases, the dystrophin and associ...

    Authors: Rubén Miranda, Flora Nagapin, Bruno Bozon, Serge Laroche, Thierry Aubin and Cyrille Vaillend

    Citation: Molecular Autism 2015 6:60

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  23. Content type: Research

    Theory-of-mind (ToM), the ability to infer people’s thoughts and feelings, is a pivotal skill in effective social interactions. Individuals with autism spectrum disorders (ASD) have been found to have altered ...

    Authors: Rajesh K. Kana, Jose O. Maximo, Diane L. Williams, Timothy A. Keller, Sarah E. Schipul, Vladimir L. Cherkassky, Nancy J. Minshew and Marcel Adam Just

    Citation: Molecular Autism 2015 6:59

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  24. Content type: Research

    Previous studies have demonstrated aggregation of autistic traits in undiagnosed family members of children with autism spectrum disorder (ASD), which has significant implications for ASD risk in their offspri...

    Authors: Thomas W. Frazier, Eric A. Youngstrom, Antonio Y. Hardan, Stelios Georgiades, John N. Constantino and Charis Eng

    Citation: Molecular Autism 2015 6:58

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  25. Content type: Research

    Platelets have been proven to be a useful cellular model to study some neuropathologies, due to the overlapping biological features between neurons and platelets as granule secreting cells. Altered platelet de...

    Authors: Nora Bijl, Chantal Thys, Christine Wittevrongel, Wouter De la Marche, Koenraad Devriendt, Hilde Peeters, Chris Van Geet and Kathleen Freson

    Citation: Molecular Autism 2015 6:57

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  26. Content type: Research

    RBFOX1 (also known as FOX1 or A2BP1) regulates alternative splicing of a variety of transcripts crucial for neuronal functions. Physiological significance of RBFOX1 during brain development is seemingly essent...

    Authors: Nanako Hamada, Hidenori Ito, Ikuko Iwamoto, Rika Morishita, Hidenori Tabata and Koh-ichi Nagata

    Citation: Molecular Autism 2015 6:56

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  27. Content type: Research

    Disruptive mutation in the CHD8 gene is one of the top genetic risk factors in autism spectrum disorders (ASDs). Previous analyses of genome-wide CHD8 occupancy and reduced expression of CHD8 by shRNA knockdown i...

    Authors: Ping Wang, Mingyan Lin, Erika Pedrosa, Anastasia Hrabovsky, Zheng Zhang, Wenjun Guo, Herbert M. Lachman and Deyou Zheng

    Citation: Molecular Autism 2015 6:55

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  28. Content type: Research

    Autism spectrum disorder (ASD) is characterized by atypical development of cortical and subcortical gray matter volume. Subcortical structural changes have been associated with restricted and repetitive behavi...

    Authors: Ian W. Eisenberg, Gregory L. Wallace, Lauren Kenworthy, Stephen J. Gotts and Alex Martin

    Citation: Molecular Autism 2015 6:54

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  29. Content type: Research

    Adolescent females with an autism spectrum disorder (ASD) are an understudied population, yet are also quite vulnerable, due to the increased complexities of social interaction and increased risk for internali...

    Authors: T. Rene Jamison and Jessica Oeth Schuttler

    Citation: Molecular Autism 2015 6:53

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  30. Content type: Research

    Evidence indicates that social functioning deficits and sensory sensitivities in autism spectrum disorder (ASD) are related to atypical sensory integration. The exact mechanisms underlying these integration di...

    Authors: Katie Greenfield, Danielle Ropar, Alastair D. Smith, Mark Carey and Roger Newport

    Citation: Molecular Autism 2015 6:51

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  31. Content type: Research

    Autism spectrum disorder (ASD) is diagnosed much less often in females than males. Emerging behavioral accounts suggest that the clinical presentation of autism is different in females and males, yet research ...

    Authors: Kaustubh Supekar and Vinod Menon

    Citation: Molecular Autism 2015 6:50

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  32. Content type: Research

    Autism spectrum conditions (ASC) are a group of neurodevelopmental conditions characterized by difficulties in social interaction and communication alongside repetitive and stereotyped behaviours. ASC are heri...

    Authors: Varun Warrier, Vivienne Chee, Paula Smith, Bhismadev Chakrabarti and Simon Baron-Cohen

    Citation: Molecular Autism 2015 6:49

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  33. Content type: Research

    Autism spectrum disorder (ASD) traits are continuously distributed throughout the population, and ASD symptoms are also frequently observed in patients with attention-deficit/hyperactivity disorder (ADHD). Bot...

    Authors: Eelco V. van Dongen, Daniel von Rhein, Laurence O’Dwyer, Barbara Franke, Catharina A. Hartman, Dirk J. Heslenfeld, Pieter J. Hoekstra, Jaap Oosterlaan, Nanda Rommelse and Jan Buitelaar

    Citation: Molecular Autism 2015 6:48

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  34. Content type: Research

    Understanding and anticipating others’ mental or emotional states relies on the processing of social cues, such as dynamic facial expressions. Individuals with high-functioning autism (HFA) may process these c...

    Authors: Letizia Palumbo, Hollie G. Burnett and Tjeerd Jellema

    Citation: Molecular Autism 2015 6:47

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  35. Content type: Research

    MicroRNAs are small RNA molecules that regulate the translation of protein from gene transcripts and are a powerful mechanism to regulate gene networks. Next-generation sequencing technologies have produced im...

    Authors: Michal Mor, Stefano Nardone, Dev Sharan Sams and Evan Elliott

    Citation: Molecular Autism 2015 6:46

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  36. Content type: Research

    Autism spectrum disorder (ASD) is highly heritable, yet genome-wide association studies (GWAS), copy number variation screens, and candidate gene association studies have found no single factor accounting for ...

    Authors: Anthony J. Griswold, Nicole D. Dueker, Derek Van Booven, Joseph A. Rantus, James M. Jaworski, Susan H. Slifer, Michael A. Schmidt, William Hulme, Ioanna Konidari, Patrice L. Whitehead, Michael L. Cuccaro, Eden R. Martin, Jonathan L. Haines, John R. Gilbert, John P. Hussman and Margaret A. Pericak-Vance

    Citation: Molecular Autism 2015 6:43

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  37. Content type: Research

    Male predominance is a prominent feature of autism spectrum disorders (ASD), with a reported male to female ratio of 4:1. Because of the overwhelming focus on males, little is known about the neuroanatomical b...

    Authors: Marie Schaer, John Kochalka, Aarthi Padmanabhan, Kaustubh Supekar and Vinod Menon

    Citation: Molecular Autism 2015 6:42

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  38. Content type: Research

    The genetics of autism spectrum disorder (hereafter referred to as “autism”) are rapidly unfolding, with a significant increase in the identification of genes implicated in the disorder. Many of these genes ar...

    Authors: Neha Uppal, Rishi Puri, Frank Yuk, William G M Janssen, Ozlem Bozdagi-Gunal, Hala Harony-Nicolas, Dara L Dickstein, Joseph D Buxbaum and Patrick R Hof

    Citation: Molecular Autism 2015 6:41

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  39. Content type: Research

    There is growing research evidence that subclinical autistic traits are elevated in relatives of individuals with autism spectrum disorder (ASD), continuously distributed in the general population and likely t...

    Authors: I. Magiati, D. A. Goh, S. J. Lim, D. Z. Q. Gan, J. C. L. Leong, C. Allison, S. Baron-Cohen, A. Rifkin-Graboi, B F P. Broekman, S-M. Saw, Y-S. Chong, K. Kwek, P. D. Gluckman, S. B. Lim and M. J. Meaney

    Citation: Molecular Autism 2015 6:40

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  40. Content type: Research

    Autism spectrum disorders (ASDs) likely involve dysregulation of multiple genes related to brain function and development. Abnormalities in individual regulatory small non-coding RNA (sncRNA), including microR...

    Authors: Bradley P. Ander, Nicole Barger, Boryana Stamova, Frank R. Sharp and Cynthia M. Schumann

    Citation: Molecular Autism 2015 6:37

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  41. Content type: Viewpoint

    One of the most consistent findings in autism spectrum disorder (ASD) research is a higher rate of ASD diagnosis in males than females. Despite this, remarkably little research has focused on the reasons for t...

    Authors: Alycia K Halladay, Somer Bishop, John N Constantino, Amy M Daniels, Katheen Koenig, Kate Palmer, Daniel Messinger, Kevin Pelphrey, Stephan J Sanders, Alison Tepper Singer, Julie Lounds Taylor and Peter Szatmari

    Citation: Molecular Autism 2015 6:36

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  42. Content type: Research

    The prevalence of autism spectrum disorders (ASDs) is higher in men than in women. The extreme male brain theory proposes that excessive prenatal testosterone activity could be a risk factor for ASDs. However,...

    Authors: Yasuhiro Masuya, Yuko Okamoto, Keisuke Inohara, Yukiko Matsumura, Toru Fujioka, Yuji Wada and Hirotaka Kosaka

    Citation: Molecular Autism 2015 6:34

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