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  1. Prospective studies of infants at high familial risk for autism spectrum disorder (ASD) have identified a number of putative early markers that are associated with ASD outcome at 3 years of age. However, some ...

    Authors: Rachael Bedford, Teodora Gliga, Elizabeth Shephard, Mayada Elsabbagh, Andrew Pickles, Tony Charman and Mark H. Johnson

    Citation: Molecular Autism 2017 8:49

    Content type: Research

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  2. Excitation/inhibition (E/I) imbalance remains a widely discussed hypothesis in autism spectrum disorders (ASD). The presence of such an imbalance may potentially define a therapeutic target for the treatment o...

    Authors: Joana Gonçalves, Inês R. Violante, José Sereno, Ricardo A. Leitão, Ying Cai, Antero Abrunhosa, Ana Paula Silva, Alcino J. Silva and Miguel Castelo-Branco

    Citation: Molecular Autism 2017 8:47

    Content type: Research

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  3. Autism spectrum disorder (ASD) is characterized by impairments in social communication and restricted or repetitive behaviors or interests. ASD is now diagnosed in more than one out of 100 children and is bias...

    Authors: Yuanlin Zou, Qiaomei Lu, Dan Zheng, Zhigang Chu, Zhaoyu Liu, Haijia Chen, Qiongfang Ruan, Xiaohu Ge, Ziyun Zhang, Xiaoyan Wang, Wenting Lou, Yongjian Huang, Yifei Wang, Xiaodong Huang, Zhengxiang Liu, Weiguo Xie…

    Citation: Molecular Autism 2017 8:46

    Content type: Research

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  4. Although the ability to make optimal decisions under uncertainty is an integral part of everyday life, individuals with autism spectrum disorder (ASD) frequently report that they experience difficulties with t...

    Authors: Junya Fujino, Shisei Tei, Ryu-ichiro Hashimoto, Takashi Itahashi, Haruhisa Ohta, Chieko Kanai, Rieko Okada, Manabu Kubota, Motoaki Nakamura, Nobumasa Kato and Hidehiko Takahashi

    Citation: Molecular Autism 2017 8:45

    Content type: Short report

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  5. Arginine vasopressin has been shown to affect social and emotional behaviors, which is mediated by the arginine vasopressin receptor (AVPR1A). Genetic polymorphisms in the AVPR1A promoter region have been identif...

    Authors: So Young Yang, Soon Ae Kim, Gang Min Hur, Mira Park, Jong-Eun Park and Hee Jeong Yoo

    Citation: Molecular Autism 2017 8:44

    Content type: Research

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  6. Methyl-CpG-binding protein-2 (MeCP2) is a critical regulator for neural development. Either loss- or gain-of-function leads to severe neurodevelopmental disorders, such as Rett syndrome (RTT) and autism spectrum ...

    Authors: Zhu Wen, Tian-Lin Cheng, Gai-zhi Li, Shi-Bang Sun, Shun-Ying Yu, Yi Zhang, Ya-Song Du and Zilong Qiu

    Citation: Molecular Autism 2017 8:43

    Content type: Research

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  7. The amygdala controls socioemotional behavior and has consistently been implicated in the etiology of autism spectrum disorder (ASD). Precocious amygdala development is commonly reported in ASD youth with the ...

    Authors: Catherine E. Barrett, Thomas M. Hennessey, Katelyn M. Gordon, Steve J. Ryan, Morgan L. McNair, Kerry J. Ressler and Donald G. Rainnie

    Citation: Molecular Autism 2017 8:42

    Content type: Research

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  8. Working memory (WM) often is impaired in autism spectrum disorder (ASD). Such impairment may underlie core deficits in cognition and social functioning. Transcranial direct current stimulation (tDCS) has been ...

    Authors: J. Jason van Steenburgh, Mark Varvaris, David J. Schretlen, Tracy D. Vannorsdall and Barry Gordon

    Citation: Molecular Autism 2017 8:40

    Content type: Research

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  9. There is a lack of agreement about functional connectivity differences in individuals with autism spectrum disorder (ASD). Studies using absolute strength have found reduced connectivity, while those using rel...

    Authors: Benjamin E. Yerys, John D. Herrington, Theodore D. Satterthwaite, Lisa Guy, Robert T. Schultz and Danielle S. Bassett

    Citation: Molecular Autism 2017 8:39

    Content type: Research

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  10. The presence of attention-deficit/hyperactive disorder (ADHD) symptoms and impaired attention performance are commonly noted in individuals with autism spectrum disorder (ASD). However, little is known about a...

    Authors: Yi-Ling Chien, Miao-Chun Chou, Yen-Nan Chiu, Wen-Jiun Chou, Yu-Yu Wu, Wen-Che Tsai and Susan Shur-Fen Gau

    Citation: Molecular Autism 2017 8:37

    Content type: Research

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  11. Both self-regulation and insistence on sameness (IS) are related to anxiety, which is a common feature of individuals with autism spectrum disorder (ASD). Here, we aimed to characterise the IS-self-regulation-...

    Authors: Mirko Uljarević, Amanda L. Richdale, David W. Evans, Ru Ying Cai and Susan R. Leekam

    Citation: Molecular Autism 2017 8:36

    Content type: Short report

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  12. Autism spectrum disorder (ASD) is a group of complex neurodevelopmental disorders with diverse clinical manifestations and symptoms. In the last 10 years, there have been significant advances in understanding ...

    Authors: Jamie Reilly, Louise Gallagher, June L. Chen, Geraldine Leader and Sanbing Shen

    Citation: Molecular Autism 2017 8:34

    Content type: Review

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  13. MicroRNAs, small non-coding RNAs, are highly expressed in the mammalian brain, and the dysregulation of microRNA levels may be involved in neurodevelopmental disorders such as autism spectrum disorder (ASD). I...

    Authors: Yuta Hara, Yukio Ago, Erika Takano, Shigeru Hasebe, Takanobu Nakazawa, Hitoshi Hashimoto, Toshio Matsuda and Kazuhiro Takuma

    Citation: Molecular Autism 2017 8:33

    Content type: Research article

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  14. Rett syndrome (RTT) is a neurodevelopmental disorder that predominantly affects girls. The majority of RTT cases are caused by de novo mutations in methyl-CpG-binding protein 2 (MECP2), and several mouse model...

    Authors: Rylan Allemang-Grand, Jacob Ellegood, Leigh Spencer Noakes, Julie Ruston, Monica Justice, Brian J. Nieman and Jason P. Lerch

    Citation: Molecular Autism 2017 8:32

    Content type: Research

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  15. Array comparative genomic hybridization (aCGH) is recommended as a first-tier genetic test for children with autism spectrum disorder (ASD). However, interpretation of results can often be challenging partly d...

    Authors: Annisa Shui Lam Mak, Annie Ting Gee Chiu, Gordon Ka Chun Leung, Christopher Chun Yu Mak, Yoyo Wing Yiu Chu, Gary Tsz Kin Mok, Wing Fai Tang, Kelvin Yuen Kwong Chan, Mary Hoi Yin Tang, Elizabeth Tak-Kwong Lau Yim, Kin Wai So, Victoria Qinchen Tao, Cheuk Wing Fung, Virginia Chun Nei Wong, Mohammed Uddin, So Lun Lee…

    Citation: Molecular Autism 2017 8:31

    Content type: Research

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  16. People with fragile X syndrome (FXS) often have deficits in social behavior, and a substantial portion meet criteria for autism spectrum disorder. Though the genetic cause of FXS is known to be due to the sile...

    Authors: Tiffany D. Rogers, Allison M. J. Anacker, Travis M. Kerr, C. Gunnar Forsberg, Jing Wang, Bing Zhang and Jeremy Veenstra-VanderWeele

    Citation: Molecular Autism 2017 8:30

    Content type: Research

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  17. The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism spectrum disorder (ASD). The current paper describes...

    Authors: Tony Charman, Eva Loth, Julian Tillmann, Daisy Crawley, Caroline Wooldridge, David Goyard, Jumana Ahmad, Bonnie Auyeung, Sara Ambrosino, Tobias Banaschewski, Simon Baron-Cohen, Sarah Baumeister, Christian Beckmann, Sven Bölte, Thomas Bourgeron, Carsten Bours…

    Citation: Molecular Autism 2017 8:27

    Content type: Research

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  18. The tremendous clinical and aetiological diversity among individuals with autism spectrum disorder (ASD) has been a major obstacle to the development of new treatments, as many may only be effective in particu...

    Authors: Eva Loth, Tony Charman, Luke Mason, Julian Tillmann, Emily J. H. Jones, Caroline Wooldridge, Jumana Ahmad, Bonnie Auyeung, Claudia Brogna, Sara Ambrosino, Tobias Banaschewski, Simon Baron-Cohen, Sarah Baumeister, Christian Beckmann, Michael Brammer, Daniel Brandeis…

    Citation: Molecular Autism 2017 8:24

    Content type: Research

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  19. Autism spectrum disorders (ASD) are etiologically heterogeneous and complex. Functional genomics work has begun to identify a diverse array of dysregulated transcriptomic programs (e.g., synaptic, immune, cell...

    Authors: Michael V. Lombardo, Eric Courchesne, Nathan E. Lewis and Tiziano Pramparo

    Citation: Molecular Autism 2017 8:29

    Content type: Research

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  20. A core difficulty for individuals with autism is making friends and successfully engaging and interacting with peers. The majority of measures to assess peer interactions are observations in a school setting o...

    Authors: Rebecca M. Jones, Andrew Pickles and Catherine Lord

    Citation: Molecular Autism 2017 8:28

    Content type: Research

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  21. Autism spectrum disorder (ASD) is a clinically and biologically heterogeneous condition characterized by social, repetitive, and sensory behavioral abnormalities. No treatments are approved for the core diagno...

    Authors: Sameer C. Dhamne, Jill L. Silverman, Chloe E. Super, Stephen H. T. Lammers, Mustafa Q. Hameed, Meera E. Modi, Nycole A. Copping, Michael C. Pride, Daniel G. Smith, Alexander Rotenberg, Jacqueline N. Crawley and Mustafa Sahin

    Citation: Molecular Autism 2017 8:26

    Content type: Research

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  22. The human somatosensory system comprises dissociable paths for discriminative and affective touch, reflected in separate peripheral afferent populations and distinct cortical targets. Differences in behavioral...

    Authors: Michelle D. Failla, Brittany R. Peters, Haleh Karbasforoushan, Jennifer H. Foss-Feig, Kimberly B. Schauder, Brynna H. Heflin and Carissa J. Cascio

    Citation: Molecular Autism 2017 8:25

    Content type: Research

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  23. Despite the fact that deficits in social communication and interaction are at the core of Autism Spectrum Conditions (ASC), no study has yet tested individuals on a continuum from neurotypical development to a...

    Authors: Arianna Curioni, Ilaria Minio-Paluello, Lucia Maria Sacheli, Matteo Candidi and Salvatore Maria Aglioti

    Citation: Molecular Autism 2017 8:23

    Content type: Research

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  24. Studies in the fmr1 KO mouse demonstrate hyper-excitability and increased high-frequency neuronal activity in sensory cortex. These abnormalities may contribute to prominent and distressing sensory hypersensitivi...

    Authors: Lauren E. Ethridge, Stormi P. White, Matthew W. Mosconi, Jun Wang, Ernest V. Pedapati, Craig A. Erickson, Matthew J. Byerly and John A. Sweeney

    Citation: Molecular Autism 2017 8:22

    Content type: Research

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    The Erratum to this article has been published in Molecular Autism 2017 8:38

  25. Autistic individuals commonly show circumscribed or “special” interests: areas of obsessive interest in a specific category. The present study investigated what impact these interests have on attention, an asp...

    Authors: Owen E. Parsons, Andrew P. Bayliss and Anna Remington

    Citation: Molecular Autism 2017 8:20

    Content type: Research

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  26. Childhood disintegrative disorder (CDD) is a rare form of autism spectrum disorder (ASD) of unknown etiology. It is characterized by late-onset regression leading to significant intellectual disability (ID) an...

    Authors: Abha R. Gupta, Alexander Westphal, Daniel Y. J. Yang, Catherine A. W. Sullivan, Jeffrey Eilbott, Samir Zaidi, Avery Voos, Brent C. Vander Wyk, Pam Ventola, Zainulabedin Waqar, Thomas V. Fernandez, A. Gulhan Ercan-Sencicek, Michael F. Walker, Murim Choi, Allison Schneider, Tammy Hedderly…

    Citation: Molecular Autism 2017 8:19

    Content type: Research

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  27. Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) symptoms and autism spectrum disorder (ASD) symptoms have been reported. Cross-trait genetic relationships are, however, subjec...

    Authors: Evie Stergiakouli, George Davey Smith, Joanna Martin, David H. Skuse, Wolfgang Viechtbauer, Susan M. Ring, Angelica Ronald, David E. Evans, Simon E. Fisher, Anita Thapar and Beate St Pourcain

    Citation: Molecular Autism 2017 8:18

    Content type: Research

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  28. Rett syndrome (RTT) is a severe, neurodevelopmental disorder primarily affecting girls, characterized by progressive loss of cognitive, social, and motor skills after a relatively brief period of typical devel...

    Authors: Dejian Zhao, Ryan Mokhtari, Erika Pedrosa, Rayna Birnbaum, Deyou Zheng and Herbert M. Lachman

    Citation: Molecular Autism 2017 8:17

    Content type: Research

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  29. Studies reporting altered susceptibility to visual illusions in autistic individuals compared to that typically developing individuals have been taken to reflect differences in perception (e.g. reduced global ...

    Authors: Catherine Manning, Michael J. Morgan, Craig T. W. Allen and Elizabeth Pellicano

    Citation: Molecular Autism 2017 8:16

    Content type: Research

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  30. Autism spectrum disorder (ASD) is one of the most highly heritable neuropsychiatric disorders, but underlying molecular mechanisms are still unresolved due to extreme locus heterogeneity. Leveraging meaningful...

    Authors: Rui Chen, Lea K. Davis, Stephen Guter, Qiang Wei, Suma Jacob, Melissa H. Potter, Nancy J. Cox, Edwin H. Cook, James S. Sutcliffe and Bingshan Li

    Citation: Molecular Autism 2017 8:14

    Content type: Research

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  31. CHD8 (chromodomain helicase DNA-binding protein 8), which codes for a member of the CHD family of ATP-dependent chromatin-remodeling factors, is one of the most commonly mutated genes ...

    Authors: Ping Wang, Ryan Mokhtari, Erika Pedrosa, Michael Kirschenbaum, Can Bayrak, Deyou Zheng and Herbert M. Lachman

    Citation: Molecular Autism 2017 8:11

    Content type: Research

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  32. According to recent evidence, up to 40–50% of variance in autism spectrum disorder (ASD) liability might be determined by environmental factors. In the present paper, we conducted a review of systematic review...

    Authors: Amirhossein Modabbernia, Eva Velthorst and Abraham Reichenberg

    Citation: Molecular Autism 2017 8:13

    Content type: Review

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  33. Autism spectrum disorder (ASD) is a neurodevelopmental disease characterized by difficulties in social communication, unusually restricted, repetitive behavior and interests, and specific abnormalities in lang...

    Authors: Dominique Endres, Ludger Tebartz van Elst, Simon A. Meyer, Bernd Feige, Kathrin Nickel, Anna Bubl, Andreas Riedel, Dieter Ebert, Thomas Lange, Volkmar Glauche, Monica Biscaldi, Alexandra Philipsen, Simon J. Maier and Evgeniy Perlov

    Citation: Molecular Autism 2017 8:10

    Content type: Research

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  34. Prenatal exposure to infection is a recognized environmental risk factor for neuropsychiatric disorders of developmental origins such as autism or schizophrenia. Experimental work in animals indicates that thi...

    Authors: Stephanie Vuillermot, Wei Luan, Urs Meyer and Darryl Eyles

    Citation: Molecular Autism 2017 8:9

    Content type: Research

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  35. Restricted and repetitive behaviors are defining features of autism spectrum disorder (ASD). Under revised diagnostic criteria for ASD, this behavioral domain now includes atypical responses to sensory stimuli...

    Authors: Jason J. Wolff, Meghan R. Swanson, Jed T. Elison, Guido Gerig, John R. Pruett Jr., Martin A. Styner, Clement Vachet, Kelly N. Botteron, Stephen R. Dager, Annette M. Estes, Heather C. Hazlett, Robert T. Schultz, Mark D. Shen, Lonnie Zwaigenbaum and Joseph Piven

    Citation: Molecular Autism 2017 8:8

    Content type: Research

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  36. Socio-emotional difficulties in autism spectrum disorder (ASD) are thought to reflect impaired functional connectivity within the “social brain”. Nonetheless, a whole-brain characterization of the fast respons...

    Authors: Rocco Mennella, Rachel C. Leung, Margot J. Taylor and Benjamin T. Dunkley

    Citation: Molecular Autism 2017 8:7

    Content type: Research

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  37. The etiology of autism, a complex, heritable, neurodevelopmental disorder, remains largely unexplained. Given the unexplained risk and recent evidence supporting a role for epigenetic mechanisms in the develop...

    Authors: Shannon E. Ellis, Simone Gupta, Anna Moes, Andrew B. West and Dan E. Arking

    Citation: Molecular Autism 2017 8:6

    Content type: Research

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  38. Autism spectrum disorders (ASD) are persistent and lifelong conditions. Despite this, almost all twin studies focus on childhood. This twin study investigated the stability of autistic traits from childhood to...

    Authors: Mark J. Taylor, Christopher Gillberg, Paul Lichtenstein and Sebastian Lundström

    Citation: Molecular Autism 2017 8:5

    Content type: Research

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  39. Autism spectrum disorder (ASD) is sexually dimorphic in brain structure, genetics, and behaviors. In studies of brain tissue, the age of the population is clearly a factor in interpreting study outcome, yet se...

    Authors: Cynthia M. Schumann, Frank R. Sharp, Bradley P. Ander and Boryana Stamova

    Citation: Molecular Autism 2017 8:4

    Content type: Short Report

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  40. Autism spectrum disorder (ASD) affects more than 1% of children in the USA. The male-to-female prevalence ratio of roughly 4:1 in ASD is a well-recognized but poorly understood phenomenon. An explicit focus on...

    Authors: Bo Y. Park, Brian K. Lee, Igor Burstyn, Loni P. Tabb, Jeff A. Keelan, Andrew J. O. Whitehouse, Lisa A. Croen, Margaret D. Fallin, Irva Hertz-Picciotto, Owen Montgomery and Craig J. Newschaffer

    Citation: Molecular Autism 2017 8:3

    Content type: Research

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  41. d-Cycloserine (DCS) enhances extinction learning across species, but it has proven challenging to identify consistent benefit of DCS when added to therapeutic interventions. We conduct...

    Authors: Logan K. Wink, Noha F. Minshawi, Rebecca C. Shaffer, Martin H. Plawecki, David J. Posey, Paul S. Horn, Ryan Adams, Ernest V. Pedapati, Tori L. Schaefer, Christopher J. McDougle, Naomi B. Swiezy and Craig A. Erickson

    Citation: Molecular Autism 2017 8:2

    Content type: Research

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  42. The causes of autism likely involve genetic and environmental factors that influence neurobiological changes and the neurological and behavioral features of the disorder. Immune factors and inflammation are hy...

    Authors: Carlos A. Pardo, Cristan A. Farmer, Audrey Thurm, Fatma M. Shebl, Jorjetta Ilieva, Simran Kalra and Susan Swedo

    Citation: Molecular Autism 2017 8:1

    Content type: Research

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  43. Children with autism spectrum conditions (ASC) have emotion recognition deficits when tested in different expression modalities (face, voice, body). However, these findings usually focus on basic emotions, usi...

    Authors: Shimrit Fridenson-Hayo, Steve Berggren, Amandine Lassalle, Shahar Tal, Delia Pigat, Sven Bölte, Simon Baron-Cohen and Ofer Golan

    Citation: Molecular Autism 2016 7:52

    Content type: Research

    Published on:

  44. Autism spectrum disorders (ASD) are increasingly prevalent neurodevelopmental disorders that are behaviorally diagnosed in early childhood. Most ASD cases likely arise from a complex mixture of genetic and env...

    Authors: Diane I. Schroeder, Rebecca J. Schmidt, Florence K. Crary-Dooley, Cheryl K. Walker, Sally Ozonoff, Daniel J. Tancredi, Irva Hertz-Picciotto and Janine M. LaSalle

    Citation: Molecular Autism 2016 7:51

    Content type: Research

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