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  1. Content type: Research

    d-Cycloserine (DCS) enhances extinction learning across species, but it has proven challenging to identify consistent benefit of DCS when added to therapeutic interventions. We conduct...

    Authors: Logan K. Wink, Noha F. Minshawi, Rebecca C. Shaffer, Martin H. Plawecki, David J. Posey, Paul S. Horn, Ryan Adams, Ernest V. Pedapati, Tori L. Schaefer, Christopher J. McDougle, Naomi B. Swiezy and Craig A. Erickson

    Citation: Molecular Autism 2017 8:2

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  2. Content type: Research

    The causes of autism likely involve genetic and environmental factors that influence neurobiological changes and the neurological and behavioral features of the disorder. Immune factors and inflammation are hy...

    Authors: Carlos A. Pardo, Cristan A. Farmer, Audrey Thurm, Fatma M. Shebl, Jorjetta Ilieva, Simran Kalra and Susan Swedo

    Citation: Molecular Autism 2017 8:1

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  3. Content type: Research

    Children with autism spectrum conditions (ASC) have emotion recognition deficits when tested in different expression modalities (face, voice, body). However, these findings usually focus on basic emotions, usi...

    Authors: Shimrit Fridenson-Hayo, Steve Berggren, Amandine Lassalle, Shahar Tal, Delia Pigat, Sven Bölte, Simon Baron-Cohen and Ofer Golan

    Citation: Molecular Autism 2016 7:52

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  4. Content type: Research

    Autism spectrum disorders (ASD) are increasingly prevalent neurodevelopmental disorders that are behaviorally diagnosed in early childhood. Most ASD cases likely arise from a complex mixture of genetic and env...

    Authors: Diane I. Schroeder, Rebecca J. Schmidt, Florence K. Crary-Dooley, Cheryl K. Walker, Sally Ozonoff, Daniel J. Tancredi, Irva Hertz-Picciotto and Janine M. LaSalle

    Citation: Molecular Autism 2016 7:51

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  5. Content type: Research

    Autism is characterised by atypical social-communicative behaviour and restricted range of interests and repetitive behaviours. These features exist in a continuum in the general population. Behavioural measur...

    Authors: Alokananda Rudra, Jai Ranjan Ram, Tom Loucas, Matthew K. Belmonte and Bhismadev Chakrabarti

    Citation: Molecular Autism 2016 7:50

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  6. Content type: Research

    Autism spectrum disorders (ASD) are complex conditions whose pathogenesis may be attributed to gene–environment interactions. There are no definitive mechanisms explaining how environmental triggers can lead t...

    Authors: Maria Fiorentino, Anna Sapone, Stefania Senger, Stephanie S. Camhi, Sarah M. Kadzielski, Timothy M. Buie, Deanna L. Kelly, Nicola Cascella and Alessio Fasano

    Citation: Molecular Autism 2016 7:49

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  7. Content type: Research

    Autism spectrum conditions (ASC) are frequently associated with motor coordination difficulties. However, no studies have explored the prevalence of dyspraxia in a large sample of individuals with and without ...

    Authors: Sarah Cassidy, Penelope Hannant, Teresa Tavassoli, Carrie Allison, Paula Smith and Simon Baron-Cohen

    Citation: Molecular Autism 2016 7:48

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  8. Content type: Research

    Autism spectrum disorder (ASD) is still diagnosed through behavioral observation, due to a lack of laboratory biomarkers, which could greatly aid clinicians in providing earlier and more reliable diagnoses. Me...

    Authors: Federica Gevi, Lello Zolla, Stefano Gabriele and Antonio M. Persico

    Citation: Molecular Autism 2016 7:47

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  9. Content type: Research

    A prominent diagnostic criterion of autism spectrum disorder (ASD) relates to the abnormal or diminished use of facial expressions. Yet little is known about the mechanisms that contribute to this feature of ASD.

    Authors: Dominic A. Trevisan, Marleis Bowering and Elina Birmingham

    Citation: Molecular Autism 2016 7:46

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  10. Content type: Short report

    Mimetic desire (MD), the spontaneous propensity to pursue goals that others pursue, is a case of social influence that is believed to shape preferences. Autism spectrum disorder (ASD) is defined by both atypic...

    Authors: Baudouin Forgeot d’Arc, Fabien Vinckier, Maël Lebreton, Isabelle Soulières, Laurent Mottron and Mathias Pessiglione

    Citation: Molecular Autism 2016 7:45

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  11. Content type: Research

    The search for genetic factors underlying autism spectrum disorders (ASD) has led to the identification of hundreds of genes containing thousands of variants that differ in mode of inheritance, effect size, fr...

    Authors: Eric Larsen, Idan Menashe, Mark N. Ziats, Wayne Pereanu, Alan Packer and Sharmila Banerjee-Basu

    Citation: Molecular Autism 2016 7:44

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  12. Content type: Research

    Fragile X syndrome (FXS), a common cause of intellectual disability and autism, results from the expansion of a CGG-repeat tract in the 5′ untranslated region of the FMR1 gene to >200 repeats. Such expanded allel...

    Authors: Yifan Zhou, Daman Kumari, Nicholas Sciascia and Karen Usdin

    Citation: Molecular Autism 2016 7:42

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  13. Content type: Research

    The insular cortex comprises multiple functionally differentiated sub-regions, each of which has different patterns of connectivity with other brain regions. Such diverse connectivity patterns are thought to u...

    Authors: Takashi Yamada, Takashi Itahashi, Motoaki Nakamura, Hiromi Watanabe, Miho Kuroda, Haruhisa Ohta, Chieko Kanai, Nobumasa Kato and Ryu-ichiro Hashimoto

    Citation: Molecular Autism 2016 7:41

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  14. Content type: Research

    Recent studies have indicated that quantitative autistic traits (QATs) of parents reflect inherited liabilities that may index background genetic risk for clinical autism spectrum disorder (ASD) in their offsp...

    Authors: Joshua Page, John Nicholas Constantino, Katherine Zambrana, Eden Martin, Ilker Tunc, Yi Zhang, Anna Abbacchi and Daniel Messinger

    Citation: Molecular Autism 2016 7:39

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  15. Content type: Research

    Impaired orienting to social stimuli is one of the core early symptoms of autism spectrum disorder (ASD). However, in contrast to faces, name processing has rarely been studied in individuals with ASD. Here, w...

    Authors: Anna Nowicka, Hanna B. Cygan, Paweł Tacikowski, Paweł Ostaszewski and Rafał Kuś

    Citation: Molecular Autism 2016 7:38

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  16. Content type: Short report

    Gastrointestinal dysfunction and gut microbial composition disturbances have been widely reported in autism spectrum disorder (ASD). This study examines whether gut microbiome disturbances are present in the BTBR

    Authors: Christopher Newell, Marc R. Bomhof, Raylene A. Reimer, Dustin S. Hittel, Jong M. Rho and Jane Shearer

    Citation: Molecular Autism 2016 7:37

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  17. Content type: Research

    Atypical lateralization of language-related functions has been repeatedly found in individuals with autism spectrum conditions (ASC). Few studies have, however, investigated deviations from typically occurring...

    Authors: Dorothea L. Floris, Anita D. Barber, Mary Beth Nebel, Mary Martinelli, Meng-Chuan Lai, Deana Crocetti, Simon Baron-Cohen, John Suckling, James J. Pekar and Stewart H. Mostofsky

    Citation: Molecular Autism 2016 7:35

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  18. Content type: Commentary

    Sibling recurrence data from the Baby Siblings Research Consortium (BSRC) recapitulate results from very large clinical family studies that demonstrate the absence of the Carter effect and provide clarificatio...

    Authors: John N. Constantino

    Citation: Molecular Autism 2016 7:32

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  19. Content type: Commentary

    Messinger et al. found a 3.18 odds ratio of male to female ASD recurrence in 1241 prospectively followed high-risk (HR) siblings. Among high-risk siblings (with and without ASD), as well as among 583 low-risk ...

    Authors: Daniel S. Messinger, Gregory S. Young, Sara Jane Webb, Sally Ozonoff, Susan E. Bryson, Alice Carter, Leslie Carver, Tony Charman, Katarzyna Chawarska, Suzanne Curtin, Karen Dobkins, Irva Hertz-Picciotto, Ted Hutman, Jana M. Iverson, Rebecca Landa, Charles A. Nelson…

    Citation: Molecular Autism 2016 7:31

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  20. Content type: Short report

    Restricted and repetitive behaviours (RRBs) constitute a core symptom domain of autism spectrum disorder (ASD). However, the nature of RRBs in the context of the Broader Autism Phenotype (BAP) is not well unde...

    Authors: Mirko Uljarević, David W. Evans, Gail A. Alvares and Andrew J. O. Whitehouse

    Citation: Molecular Autism 2016 7:29

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  21. Content type: Research

    While asymmetry in the fusiform gyrus (FFG) has been reported in functional and structural studies in typically developing controls (TDC), few studies have examined FFG asymmetry in autism spectrum disorder (A...

    Authors: Chase C. Dougherty, David W. Evans, Gajendra J. Katuwal and Andrew M. Michael

    Citation: Molecular Autism 2016 7:28

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  22. Content type: Research

    Widespread use of microarray technology has led to increasing identification of 22q11.2 duplication syndrome (22q11.2DupS), the reciprocal syndrome of the well-characterized 22q11.2 deletion syndrome (22q11.2D...

    Authors: Tara L. Wenger, Judith S. Miller, Lauren M. DePolo, Ashley B. de Marchena, Caitlin C. Clements, Beverly S. Emanuel, Elaine H. Zackai, Donna M. McDonald-McGinn and Robert T. Schultz

    Citation: Molecular Autism 2016 7:27

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    The Erratum to this article has been published in Molecular Autism 2016 7:34

  23. Content type: Research

    Social impairment is a defining feature of autism spectrum disorder (ASD) with no demonstrated effective pharmacologic treatments. The goal of this study was to evaluate efficacy, safety, and tolerability of o...

    Authors: Logan K. Wink, Ryan Adams, Zemin Wang, James E. Klaunig, Martin H. Plawecki, David J. Posey, Christopher J. McDougle and Craig A. Erickson

    Citation: Molecular Autism 2016 7:26

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  24. Content type: Research

    Autism Spectrum Conditions (ASC) are associated with a range of perceptual atypicalities, including abnormalities in gaze processing. Pellicano and Burr (Trends Cogn Sci 16(10):504-10, 2012) have argued that t...

    Authors: Philip J. Pell, Isabelle Mareschal, Andrew J. Calder, Elisabeth A. H. von dem Hagen, Colin W.G. Clifford, Simon Baron-Cohen and Michael P. Ewbank

    Citation: Molecular Autism 2016 7:25

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  25. Content type: Research

    Recent research has identified differences in relative attention to competing social versus non-social video stimuli in individuals with autism spectrum disorder (ASD). Whether attentional allocation is influe...

    Authors: Hayley Crawford, Joanna Moss, Chris Oliver, Natasha Elliott, Giles M. Anderson and Joseph P. McCleery

    Citation: Molecular Autism 2016 7:24

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  26. Content type: Research

    Autism spectrum disorder (ASD) is an early-onset neurodevelopmental disorder with complex genetic underpinning in its etiology. Copy number variations (CNVs) as one of the genetic factors associated with ASD h...

    Authors: Chia-Lin Yin, Hsin-I Chen, Ling-Hui Li, Yi-Ling Chien, Hsiao-Mei Liao, Miao Chun Chou, Wen-Jiun Chou, Wen-Che Tsai, Yen-Nan Chiu, Yu-Yu Wu, Chen-Zen Lo, Jer-Yuarn Wu, Yuan-Tsong Chen and Susan Shur-Fen Gau

    Citation: Molecular Autism 2016 7:23

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  27. Content type: Research

    BMP/RA-inducible neural-specific protein 1 (Brinp1) is highly conserved in vertebrates, and continuously expressed in the neocortex, hippocampus, olfactory bulb and cerebellum from mid-embryonic development throu...

    Authors: Susan R. Berkowicz, Travis J. Featherby, Zhengdong Qu, Aminah Giousoh, Natalie A. Borg, Julian I. Heng, James C. Whisstock and Phillip I. Bird

    Citation: Molecular Autism 2016 7:22

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  28. Content type: Research

    Although it is well established that the prevalence of autism spectrum disorder (ASD) is higher in males than females, there is relatively little understanding of the underlying mechanisms and their developmen...

    Authors: Rachael Bedford, Emily J. H. Jones, Mark H. Johnson, Andrew Pickles, Tony Charman and Teodora Gliga

    Citation: Molecular Autism 2016 7:21

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    The Erratum to this article has been published in Molecular Autism 2016 7:33

  29. Content type: Research

    Gaze abnormality is a diagnostic criterion for autism spectrum disorder (ASD). However, few easy-to-use clinical tools exist to evaluate the unique eye-gaze patterns of ASD. Recently, we developed Gazefinder, ...

    Authors: Toru Fujioka, Keisuke Inohara, Yuko Okamoto, Yasuhiro Masuya, Makoto Ishitobi, Daisuke N. Saito, Minyoung Jung, Sumiyoshi Arai, Yukiko Matsumura, Takashi X. Fujisawa, Kosuke Narita, Katsuaki Suzuki, Kenji J. Tsuchiya, Norio Mori, Taiichi Katayama, Makoto Sato…

    Citation: Molecular Autism 2016 7:19

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  30. Content type: Research

    Intellectual disability (ID), autism, and epilepsy share frequent yet variable comorbidities with one another. In order to better understand potential genetic divergence underlying this variable risk, we studi...

    Authors: Emily L. Casanova, Julia L. Sharp, Hrishikesh Chakraborty, Nahid Sultana Sumi and Manuel F. Casanova

    Citation: Molecular Autism 2016 7:18

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  31. Content type: Research

    Fragile X syndrome (FXS) is a single-gene disorder that is the most common heritable cause of intellectual disability and the most frequent monogenic cause of autism spectrum disorders (ASD). FXS is caused by ...

    Authors: Jantine A. C. Broek, Zhanmin Lin, H. Martijn de Gruiter, Heleen van ‘t Spijker, Elize D. Haasdijk, David Cox, Sureyya Ozcan, Gert W. A. van Cappellen, Adriaan B. Houtsmuller, Rob Willemsen, Chris I. de Zeeuw and Sabine Bahn

    Citation: Molecular Autism 2016 7:17

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  32. Content type: Research

    Autism spectrum disorders (ASDs) represent a heterogeneous group of disorders with a wide range of behavioral impairments including social and communication deficits. Apart from these core symptoms, a signific...

    Authors: Anwesha Banerjee, Jonathan A. Luong, Anthony Ho, Aeshah O. Saib and Jonathan E. Ploski

    Citation: Molecular Autism 2016 7:16

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  33. Content type: Short report

    Some previous research has suggested that testosterone prenatally contributes to gender differences in autistic traits, but little is known about the role of testosterone during early postnatal development (mi...

    Authors: Karson T. F. Kung, Mihaela Constantinescu, Wendy V. Browne, Rebecca M. Noorderhaven and Melissa Hines

    Citation: Molecular Autism 2016 7:15

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  34. Content type: Research

    Amygdala dysfunction is hypothesized to underlie the social deficits observed in autism spectrum disorders (ASD). However, the neurobiological basis of this hypothesis is underspecified because it is unknown w...

    Authors: Annika Rausch, Wei Zhang, Koen V. Haak, Maarten Mennes, Erno J. Hermans, Erik van Oort, Guido van Wingen, Christian F. Beckmann, Jan K. Buitelaar and Wouter B. Groen

    Citation: Molecular Autism 2016 7:13

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  35. Content type: Research

    The ability to follow gaze is an important prerequisite for joint attention, which is often compromised in children with autism spectrum disorder (ASD). The direction of both the head and eyes provides cues to...

    Authors: Emilia Thorup, Pär Nyström, Gustaf Gredebäck, Sven Bölte and Terje Falck-Ytter

    Citation: Molecular Autism 2016 7:12

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  36. Content type: Research

    Individuals with autism spectrum disorder (ASD) have been characterized by altered cerebral cortical structures; however, the field has yet to identify consistent markers and prior studies have included mostly...

    Authors: Daniel Y.-J. Yang, Danielle Beam, Kevin A. Pelphrey, Sebiha Abdullahi and Roger J. Jou

    Citation: Molecular Autism 2016 7:11

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  37. Content type: Research

    Autism spectrum conditions (autism) are diagnosed more frequently in boys than in girls. Females with autism may have been under-identified due to not only a male-biased understanding of autism but also female...

    Authors: Agnieszka Rynkiewicz, Björn Schuller, Erik Marchi, Stefano Piana, Antonio Camurri, Amandine Lassalle and Simon Baron-Cohen

    Citation: Molecular Autism 2016 7:10

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  38. Content type: Review

    Growing evidence points toward a critical role for early (prenatal) atypical neurodevelopmental processes in the aetiology of autism spectrum condition (ASC). One such process that could impact early neural de...

    Authors: Adam M. H. Young, Bhismadev Chakrabarti, David Roberts, Meng-Chuan Lai, John Suckling and Simon Baron-Cohen

    Citation: Molecular Autism 2016 7:9

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  39. Content type: Research

    Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders thought to have both genetic and environmental causes. It has been hypothesized that exposure...

    Authors: Jonna Maria Eriksson, Sebastian Lundström, Paul Lichtenstein, Susanne Bejerot and Elias Eriksson

    Citation: Molecular Autism 2016 7:8

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  40. Content type: Research

    Atypical responsiveness to olfactory stimuli has been reported as the strongest predictor of social impairment in children with autism spectrum disorders (ASD). However, previous laboratory-based sensory psych...

    Authors: Hirokazu Kumazaki, Taro Muramatsu, Takashi X. Fujisawa, Masutomo Miyao, Eri Matsuura, Ken-ichi Okada, Hirotaka Kosaka, Akemi Tomoda and Masaru Mimura

    Citation: Molecular Autism 2016 7:6

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  41. Content type: Research

    Genetic, hormonal, and environmental factors contribute since infancy to sexual dimorphism in regional brain structures of subjects with typical development. However, the neuroanatomical differences between ma...

    Authors: Alessandra Retico, Alessia Giuliano, Raffaella Tancredi, Angela Cosenza, Fabio Apicella, Antonio Narzisi, Laura Biagi, Michela Tosetti, Filippo Muratori and Sara Calderoni

    Citation: Molecular Autism 2016 7:5

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  42. Content type: Research

    As evidenced in the DSM-V, autism spectrum disorders (ASD) are often characterized by atypical sensory behavior (hyper- or hypo-reactivity), but very few studies have evaluated olfactory abilities in individua...

    Authors: Bruno Wicker, Elisabetta Monfardini and Jean-Pierre Royet

    Citation: Molecular Autism 2016 7:4

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