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  1. Autistic people and those with high autistic traits are at high risk of experiencing suicidality. Yet, there are no suicidality assessment tools developed or validated for these groups.

    Authors: Sarah A. Cassidy, Louise Bradley, Heather Cogger-Ward and Jacqui Rodgers
    Citation: Molecular Autism 2021 12:46
  2. Authors: Andrew W. Zimmerman, Kanwaljit Singh, Susan L. Connors, Hua Liu, Anita A. Panjwani, Li‑Ching Lee, Eileen Diggins, Ann Foley, Stepan Melnyk, Indrapal N. Singh, S. Jill James, Richard E. Frye and Jed W. Fahey
    Citation: Molecular Autism 2021 12:44

    The original article was published in Molecular Autism 2021 12:38

  3. Neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) display a strong male bias. Androgen exposure is profoundly increased in typical male development, but it also varies within the sexes...

    Authors: Brooke G. McKenna, Yongchao Huang, Kévin Vervier, Dabney Hofammann, Mary Cafferata, Seima Al-Momani, Florencia Lowenthal, Angela Zhang, Jin-Young Koh, Savantha Thenuwara, Leo Brueggeman, Ethan Bahl, Tanner Koomar, Natalie Pottschmidt, Taylor Kalmus, Lucas Casten…
    Citation: Molecular Autism 2021 12:43
  4. Individuals on the autism spectrum are reported to display alterations in interoception, the sense of the internal state of the body. The Interoception Sensory Questionnaire (ISQ) is a 20-item self-report meas...

    Authors: Evan Suzman, Zachary J. Williams, Jacob I. Feldman, Michelle Failla, Carissa J. Cascio, Mark T. Wallace, Maria Niarchou, James S. Sutcliffe, Ericka Wodka and Tiffany G. Woynaroski
    Citation: Molecular Autism 2021 12:42
  5. Autism spectrum disorder (ASD) has a strong genetic etiology. Germline mutation in the tumor suppressor gene PTEN is one of the best described monogenic risk cases for ASD. Animal modeling of cell-specific Pten l...

    Authors: Nick Sarn, Stetson Thacker, Hyunpil Lee and Charis Eng
    Citation: Molecular Autism 2021 12:41
  6. This article has been retracted. Please see the Retraction Notice for more detail:

    Authors: Zachary J. Williams and Katherine O. Gotham
    Citation: Molecular Autism 2021 12:40

    The original article was published in Molecular Autism 2021 12:20

  7. Restricted and repetitive behaviors (RRB) in autism spectrum disorder (ASD) encompass several distinct domains. However, commonly used general ASD measures provide broad RRB scores rather than assessing separa...

    Authors: Mirko Uljarević, Booil Jo, Thomas W. Frazier, Lawrence Scahill, Eric A. Youngstrom and Antonio Y. Hardan
    Citation: Molecular Autism 2021 12:39
  8. Sulforaphane (SF), an isothiocyanate in broccoli, has potential benefits relevant to autism spectrum disorder (ASD) through its effects on several metabolic and immunologic pathways. Previous clinical trials o...

    Authors: Andrew W. Zimmerman, Kanwaljit Singh, Susan L. Connors, Hua Liu, Anita A. Panjwani, Li-Ching Lee, Eileen Diggins, Ann Foley, Stepan Melnyk, Indrapal N. Singh, S. Jill James, Richard E. Frye and Jed W. Fahey
    Citation: Molecular Autism 2021 12:38

    The Correction to this article has been published in Molecular Autism 2021 12:44

  9. Traits and characteristics qualitatively similar to those seen in diagnosed autism spectrum disorder can be found to varying degrees in the general population. To measure these traits and facilitate their use ...

    Authors: Michael C. W. English, Gilles E. Gignac, Troy A. W. Visser, Andrew J. O. Whitehouse, James T. Enns and Murray T. Maybery
    Citation: Molecular Autism 2021 12:37

    The Correction to this article has been published in Molecular Autism 2021 12:70

  10. DDX3X syndrome is a recently identified genetic disorder that accounts for 1–3% of cases of unexplained developmental delay and/or intellectual disability (ID) in females, and is associated with motor and lang...

    Authors: Lara Tang, Tess Levy, Sylvia Guillory, Danielle Halpern, Jessica Zweifach, Ivy Giserman-Kiss, Jennifer H. Foss-Feig, Yitzchak Frank, Reymundo Lozano, Puneet Belani, Christina Layton, Bonnie Lerman, Emanuel Frowner, Michael S. Breen, Silvia De Rubeis, Ana Kostic…
    Citation: Molecular Autism 2021 12:36
  11. Language delay is one of the major referral criteria for an autism evaluation. Once an autism spectrum diagnosis is established, the language prognosis is among the main parental concerns. Early language regre...

    Authors: David Gagnon, Abderrahim Zeribi, Élise Douard, Valérie Courchesne, Borja Rodríguez-Herreros, Guillaume Huguet, Sébastien Jacquemont, Mor Absa Loum and Laurent Mottron
    Citation: Molecular Autism 2021 12:35
  12. Autism has previously been characterized by both structural and functional differences in brain connectivity. However, while the literature on single-subject derivations of functional connectivity is extensive...

    Authors: Matthew J. Leming, Simon Baron-Cohen and John Suckling
    Citation: Molecular Autism 2021 12:34
  13. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Jessica A. Jiménez, Travis S. Ptacek, Alex H. Tuttle, Ralf S. Schmid, Sheryl S. Moy, Jeremy M. Simon and Mark J. Zylka
    Citation: Molecular Autism 2021 12:33

    The original article was published in Molecular Autism 2020 11:74

  14. Intervention during the first years of life for children with autism spectrum disorder (ASD) may have the strongest impact on long-term brain development and functioning. Yet, barriers such as a shortage of tr...

    Authors: Allison L. Wainer, Zachary E. Arnold, Caroline Leonczyk and Latha Valluripalli Soorya
    Citation: Molecular Autism 2021 12:32
  15. Phelan-McDermid Syndrome (PMS) is a rare condition caused by deletion or mutation of the SHANK3 gene. Individuals with PMS frequently present with intellectual disability, autism spectrum disorder, and other neur...

    Authors: Michael. G. Mariscal, Elizabeth Berry-Kravis, Joseph D. Buxbaum, Lauren E. Ethridge, Rajna Filip-Dhima, Jennifer H. Foss-Feig, Alexander Kolevzon, Meera. E. Modi, Matthew W. Mosconi, Charles A. Nelson, Craig M. Powell, Paige M. Siper, Latha Soorya, Andrew Thaliath, Audrey Thurm, Bo Zhang…
    Citation: Molecular Autism 2021 12:29
  16. Unusual behavioral reactions to sensory stimuli are frequently reported in individuals on the autism spectrum (AS). Despite the early emergence of sensory features (< age 3) and their potential impact on devel...

    Authors: Svenja Espenhahn, Kate J. Godfrey, Sakshi Kaur, Maia Ross, Niloy Nath, Olesya Dmitrieva, Carly McMorris, Filomeno Cortese, Charlene Wright, Kara Murias, Deborah Dewey, Andrea B. Protzner, Adam McCrimmon, Signe Bray and Ashley D. Harris
    Citation: Molecular Autism 2021 12:26
  17. One of the causal mechanisms underlying neurodevelopmental disorders (NDDs) is chromatin modification and the genes that regulate chromatin. AT-rich interactive domain 1B (ARID1B), a chromatin modifier, has been ...

    Authors: J. Ellegood, S. P. Petkova, A. Kinman, L. R. Qiu, A. Adhikari, A. A. Wade, D. Fernandes, Z. Lindenmaier, A. Creighton, L. M. J. Nutter, A. S. Nord, J. L. Silverman and J. P. Lerch
    Citation: Molecular Autism 2021 12:25
  18. The Early Markers for Autism (EMA) study is a population-based case–control study designed to learn more about early biologic processes involved in ASD.

    Authors: Kristen Lyall, Jennifer L. Ames, Michelle Pearl, Michela Traglia, Lauren A. Weiss, Gayle C. Windham, Martin Kharrazi, Cathleen K. Yoshida, Robert Yolken, Heather E. Volk, Paul Ashwood, Judy Van de Water and Lisa A. Croen
    Citation: Molecular Autism 2021 12:24
  19. Autism spectrum disorders (ASD) are synaptopathies characterized by area-specific synaptic alterations and neuroinflammation. Structural and adhesive features of hippocampal synapses have been described in the...

    Authors: Marianela Evelyn Traetta, Martín Gabriel Codagnone, Nonthué Alejandra Uccelli, Alberto Javier Ramos, Sandra Zárate and Analía Reinés
    Citation: Molecular Autism 2021 12:23
  20. The social domain of autism has been studied in depth, but the relationship between the non-social traits of autism has received less attention. The Diagnostic and Statistical Manual of Mental Disorders (DSM-5...

    Authors: Rachel Grove, Sander Begeer, Anke M. Scheeren, Ricarda F. Weiland and Rosa A. Hoekstra
    Citation: Molecular Autism 2021 12:22
  21. Alexithymia, a personality trait characterized by difficulties interpreting one’s own emotional states, is commonly elevated in autistic adults, and a growing body of literature suggests that this trait underl...

    Authors: Zachary J. Williams and Katherine O. Gotham
    Citation: Molecular Autism 2021 12:20

    The Retraction Note to this article has been published in Molecular Autism 2021 12:40

  22. Marked sex differences in autism prevalence accentuate the need to understand the role of biological sex-related factors in autism. Efforts to unravel sex differences in the brain organization of autism have, ...

    Authors: Dorothea L. Floris, José O. A. Filho, Meng-Chuan Lai, Steve Giavasis, Marianne Oldehinkel, Maarten Mennes, Tony Charman, Julian Tillmann, Guillaume Dumas, Christine Ecker, Flavio Dell’Acqua, Tobias Banaschewski, Carolin Moessnang, Simon Baron-Cohen, Sarah Durston, Eva Loth…
    Citation: Molecular Autism 2021 12:19
  23. Sleep disorders are common in people with intellectual disability (ID) and autism, with growing evidence of diverse sleep profiles across ID associated genetic syndromes. Documenting the prevalence and profile...

    Authors: Georgie Agar, Chloe Brown, Daniel Sutherland, Sean Coulborn, Chris Oliver and Caroline Richards
    Citation: Molecular Autism 2021 12:18
  24. CHD8 haploinsufficiency causes autism and macrocephaly with high penetrance in the human population. Chd8 heterozygous mice exhibit relatively subtle brain overgrowth and little gene expression changes in the emb...

    Authors: Shaun Hurley, Conor Mohan, Philipp Suetterlin, Robert Ellingford, Kimberley L. H. Riegman, Jacob Ellegood, Angela Caruso, Caterina Michetti, Olivier Brock, Romy Evans, Fabrizio Rudari, Alessio Delogu, Maria Luisa Scattoni, Jason P. Lerch, Cathy Fernandes and M. Albert Basson
    Citation: Molecular Autism 2021 12:16
  25. Oxytocin is expected as a novel therapeutic agent for autism spectrum disorder (ASD) core symptoms. However, previous results on the efficacy of repeated administrations of oxytocin are controversial. Recently...

    Authors: Yasuhiko Kato, Hitoshi Kuwabara, Takashi Okada, Toshio Munesue, Seico Benner, Miho Kuroda, Masaki Kojima, Walid Yassin, Yosuke Eriguchi, Yosuke Kameno, Chihiro Murayama, Tomoko Nishimura, Kenji Tsuchiya, Kiyoto Kasai, Norio Ozaki, Hirotaka Kosaka…
    Citation: Molecular Autism 2021 12:15
  26. Autism spectrum disorder (ASD) is associated with deficits in executive functioning (EF), and these have been suggested to contribute to core as well as co-occurring psychiatric symptoms. The biological basis ...

    Authors: Robert H. Wichers, James L. Findon, Auke Jelsma, Vincent Giampietro, Vladimira Stoencheva, Dene M. Robertson, Clodagh M. Murphy, Sarah Blainey, Grainne McAlonan, Christine Ecker, Katya Rubia, Declan G. M. Murphy and Eileen M. Daly
    Citation: Molecular Autism 2021 12:14
  27. There is inconsistent evidence for a clear pattern of association between ‘camouflaging’ (strategies used to mask and/or compensate for autism characteristics during social interactions) and mental health.

    Authors: Laura Hull, Lily Levy, Meng-Chuan Lai, K. V. Petrides, Simon Baron-Cohen, Carrie Allison, Paula Smith and Will Mandy
    Citation: Molecular Autism 2021 12:13
  28. Autism spectrum disorder (ASD) is a complex neurodevelopmental condition whose biological basis is yet to be elucidated. The Australian Autism Biobank (AAB) is an initiative of the Cooperative Research Centre ...

    Authors: Chloe X. Yap, Gail A. Alvares, Anjali K. Henders, Tian Lin, Leanne Wallace, Alaina Farrelly, Tiana McLaren, Jolene Berry, Anna A. E. Vinkhuyzen, Maciej Trzaskowski, Jian Zeng, Yuanhao Yang, Dominique Cleary, Rachel Grove, Claire Hafekost, Alexis Harun…
    Citation: Molecular Autism 2021 12:12
  29. There is a strong research imperative to investigate effective treatment options for adolescents and adults with autism spectrum disorder (ASD). Elevated social anxiety, difficulties with social functioning an...

    Authors: Emily R. Bemmer, Kelsie A. Boulton, Emma E. Thomas, Ben Larke, Suncica Lah, Ian B. Hickie and Adam J. Guastella
    Citation: Molecular Autism 2021 12:11
  30. Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders characterized by impaired social interactions as well as the presentation of restrictive and repetitive behaviors. ASD is highly...

    Authors: Greta Pintacuda, Jacqueline M. Martín and Kevin C. Eggan
    Citation: Molecular Autism 2021 12:10
  31. Sensory processing atypicalities are frequent in Autism Spectrum Disorder (ASD) and neurodevelopmental disorders (NDD). Different domains of sensory processing appear to be differentially altered in these diso...

    Authors: Joana Maria Almeida Osório, Borja Rodríguez-Herreros, David Romascano, Vincent Junod, Aline Habegger, Aurélie Pain, Sonia Richetin, Paola Yu, Bertrand Isidor, Lionel Van Maldergem, Linda Pons, Sabine Manificat, Nadia Chabane, Marine Jequier Gygax and Anne Manuela Maillard
    Citation: Molecular Autism 2021 12:8
  32. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Lucia Janickova, Karin Farah Rechberger, Lucas Wey and Beat Schwaller
    Citation: Molecular Autism 2021 12:7

    The original article was published in Molecular Autism 2020 11:47

  33. Endocannabinoid dysfunction in animal models of autism spectrum disorder (ASD) and accumulating, albeit anecdotal, evidence for efficacy in humans motivated this placebo-controlled double-blind comparison of t...

    Authors: Adi Aran, Moria Harel, Hanoch Cassuto, Lola Polyansky, Aviad Schnapp, Nadia Wattad, Dorit Shmueli, Daphna Golan and F. Xavier Castellanos
    Citation: Molecular Autism 2021 12:6
  34. PTEN is a well-established risk gene for autism spectrum disorder (ASD). Yet, little is known about how PTEN mutations and associated molecular processes influence neurobehavioral function in mutation carriers wi...

    Authors: Thomas W. Frazier, Ritika Jaini, Robyn M. Busch, Matthew Wolf, Tammy Sadler, Patricia Klaas, Antonio Y. Hardan, Julian A. Martinez-Agosto, Mustafa Sahin and Charis Eng
    Citation: Molecular Autism 2021 12:5
  35. The inability to observe relevant biological processes in vivo significantly restricts human neurodevelopmental research. Advances in appropriate in vitro model systems, including patient-specific human brain ...

    Authors: Dwaipayan Adhya, George Chennell, James A. Crowe, Eva P. Valencia-Alarcón, James Seyforth, Neveen A. Hosny, Marina V. Yasvoina, Robert Forster, Simon Baron-Cohen, Anthony C. Vernon and Deepak P. Srivastava
    Citation: Molecular Autism 2021 12:4
  36. Autism is characterised not only by impaired social cognitive ‘empathising’ but also by superior rule-based ‘systemising’. These cognitive domains intertwine within the categorical diagnosis of autism, yet beh...

    Authors: Subhadip Paul, Aditi Arora, Rashi Midha, Dinh Vu, Prasun K. Roy and Matthew K. Belmonte
    Citation: Molecular Autism 2021 12:3
  37. Contrasting findings were reported in several animal models with a Shank3 mutation used to induce various autism spectrum disorder (ASD) symptoms. Here, we aimed at investigating behavioral, cellular, and molecul...

    Authors: Emmanuel Matas, Alexandre Maisterrena, Mathieu Thabault, Eric Balado, Maureen Francheteau, Anais Balbous, Laurie Galvan and Mohamed Jaber
    Citation: Molecular Autism 2021 12:2
  38. Gene copy number variants play an important role in the occurrence of neurodevelopmental disorders. Particularly, the deletion of the 16p11.2 locus is associated with autism spectrum disorder, intellectual dis...

    Authors: Sandra Martin Lorenzo, Valérie Nalesso, Claire Chevalier, Marie-Christine Birling and Yann Herault
    Citation: Molecular Autism 2021 12:1
  39. Deficits in perception and production of vocal pitch are often observed in people with autism spectrum disorder (ASD), but the neural basis of these deficits is unknown. In magnetoencephalogram (MEG), spectral...

    Authors: T. A. Stroganova, K. S. Komarov, O. V. Sysoeva, D. E. Goiaeva, T. S. Obukhova, T. M. Ovsiannikova, A. O. Prokofyev and E. V. Orekhova
    Citation: Molecular Autism 2020 11:100
  40. The controlled differentiation of pluripotent stem cells (PSCs) into neurons and glia offers a unique opportunity to study early stages of human central nervous system development under controlled conditions i...

    Authors: Arquimedes Cheffer, Lea Jessica Flitsch, Tamara Krutenko, Pascal Röderer, Liubov Sokhranyaeva, Vira Iefremova, Mohamad Hajo, Michael Peitz, Martin Karl Schwarz and Oliver Brüstle
    Citation: Molecular Autism 2020 11:99
  41. The relationships between specific genetic aetiology and phenotype in neurodevelopmental disorders are complex and hotly contested. Genes associated with intellectual disability (ID) can be grouped into networ...

    Authors: Diandra Brkić, Elise Ng-Cordell, Sinéad O’Brien, Gaia Scerif, Duncan Astle and Kate Baker
    Citation: Molecular Autism 2020 11:98
  42. Children born extremely preterm are at heightened risk for intellectual and social impairment, including Autism Spectrum Disorder (ASD). There is increasing evidence for a key role of the placenta in prenatal ...

    Authors: Hudson P. Santos Jr, Arjun Bhattacharya, Robert M. Joseph, Lisa Smeester, Karl C. K. Kuban, Carmen J. Marsit, T. Michael O’Shea and Rebecca C. Fry
    Citation: Molecular Autism 2020 11:97
  43. Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders which are more common in males. The ‘prenatal sex steroid’ hypothesis links excessive sex-steroid exposure during foetal life with the ...

    Authors: Asad Amanat Ali, Xiaoying Cui, Renata Aparecida Nedel Pertile, Xiang Li, Gregory Medley, Suzanne Adele Alexander, Andrew J. O. Whitehouse, John Joseph McGrath and Darryl Walter Eyles
    Citation: Molecular Autism 2020 11:96

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