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  1. Content type: Commentary

    Sibling recurrence data from the Baby Siblings Research Consortium (BSRC) recapitulate results from very large clinical family studies that demonstrate the absence of the Carter effect and provide clarificatio...

    Authors: John N. Constantino

    Citation: Molecular Autism 2016 7:32

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  2. Content type: Commentary

    Messinger et al. found a 3.18 odds ratio of male to female ASD recurrence in 1241 prospectively followed high-risk (HR) siblings. Among high-risk siblings (with and without ASD), as well as among 583 low-risk ...

    Authors: Daniel S. Messinger, Gregory S. Young, Sara Jane Webb, Sally Ozonoff, Susan E. Bryson, Alice Carter, Leslie Carver, Tony Charman, Katarzyna Chawarska, Suzanne Curtin, Karen Dobkins, Irva Hertz-Picciotto, Ted Hutman, Jana M. Iverson, Rebecca Landa, Charles A. Nelson…

    Citation: Molecular Autism 2016 7:31

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  3. Content type: Short report

    Restricted and repetitive behaviours (RRBs) constitute a core symptom domain of autism spectrum disorder (ASD). However, the nature of RRBs in the context of the Broader Autism Phenotype (BAP) is not well unde...

    Authors: Mirko Uljarević, David W. Evans, Gail A. Alvares and Andrew J. O. Whitehouse

    Citation: Molecular Autism 2016 7:29

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  4. Content type: Research

    While asymmetry in the fusiform gyrus (FFG) has been reported in functional and structural studies in typically developing controls (TDC), few studies have examined FFG asymmetry in autism spectrum disorder (A...

    Authors: Chase C. Dougherty, David W. Evans, Gajendra J. Katuwal and Andrew M. Michael

    Citation: Molecular Autism 2016 7:28

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  5. Content type: Research

    Widespread use of microarray technology has led to increasing identification of 22q11.2 duplication syndrome (22q11.2DupS), the reciprocal syndrome of the well-characterized 22q11.2 deletion syndrome (22q11.2D...

    Authors: Tara L. Wenger, Judith S. Miller, Lauren M. DePolo, Ashley B. de Marchena, Caitlin C. Clements, Beverly S. Emanuel, Elaine H. Zackai, Donna M. McDonald-McGinn and Robert T. Schultz

    Citation: Molecular Autism 2016 7:27

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    The Erratum to this article has been published in Molecular Autism 2016 7:34

  6. Content type: Research

    Social impairment is a defining feature of autism spectrum disorder (ASD) with no demonstrated effective pharmacologic treatments. The goal of this study was to evaluate efficacy, safety, and tolerability of o...

    Authors: Logan K. Wink, Ryan Adams, Zemin Wang, James E. Klaunig, Martin H. Plawecki, David J. Posey, Christopher J. McDougle and Craig A. Erickson

    Citation: Molecular Autism 2016 7:26

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  7. Content type: Research

    Autism Spectrum Conditions (ASC) are associated with a range of perceptual atypicalities, including abnormalities in gaze processing. Pellicano and Burr (Trends Cogn Sci 16(10):504-10, 2012) have argued that t...

    Authors: Philip J. Pell, Isabelle Mareschal, Andrew J. Calder, Elisabeth A. H. von dem Hagen, Colin W.G. Clifford, Simon Baron-Cohen and Michael P. Ewbank

    Citation: Molecular Autism 2016 7:25

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  8. Content type: Research

    Recent research has identified differences in relative attention to competing social versus non-social video stimuli in individuals with autism spectrum disorder (ASD). Whether attentional allocation is influe...

    Authors: Hayley Crawford, Joanna Moss, Chris Oliver, Natasha Elliott, Giles M. Anderson and Joseph P. McCleery

    Citation: Molecular Autism 2016 7:24

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  9. Content type: Research

    Autism spectrum disorder (ASD) is an early-onset neurodevelopmental disorder with complex genetic underpinning in its etiology. Copy number variations (CNVs) as one of the genetic factors associated with ASD h...

    Authors: Chia-Lin Yin, Hsin-I Chen, Ling-Hui Li, Yi-Ling Chien, Hsiao-Mei Liao, Miao Chun Chou, Wen-Jiun Chou, Wen-Che Tsai, Yen-Nan Chiu, Yu-Yu Wu, Chen-Zen Lo, Jer-Yuarn Wu, Yuan-Tsong Chen and Susan Shur-Fen Gau

    Citation: Molecular Autism 2016 7:23

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  10. Content type: Research

    BMP/RA-inducible neural-specific protein 1 (Brinp1) is highly conserved in vertebrates, and continuously expressed in the neocortex, hippocampus, olfactory bulb and cerebellum from mid-embryonic development throu...

    Authors: Susan R. Berkowicz, Travis J. Featherby, Zhengdong Qu, Aminah Giousoh, Natalie A. Borg, Julian I. Heng, James C. Whisstock and Phillip I. Bird

    Citation: Molecular Autism 2016 7:22

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  11. Content type: Research

    Although it is well established that the prevalence of autism spectrum disorder (ASD) is higher in males than females, there is relatively little understanding of the underlying mechanisms and their developmen...

    Authors: Rachael Bedford, Emily J. H. Jones, Mark H. Johnson, Andrew Pickles, Tony Charman and Teodora Gliga

    Citation: Molecular Autism 2016 7:21

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    The Erratum to this article has been published in Molecular Autism 2016 7:33

  12. Content type: Research

    Gaze abnormality is a diagnostic criterion for autism spectrum disorder (ASD). However, few easy-to-use clinical tools exist to evaluate the unique eye-gaze patterns of ASD. Recently, we developed Gazefinder, ...

    Authors: Toru Fujioka, Keisuke Inohara, Yuko Okamoto, Yasuhiro Masuya, Makoto Ishitobi, Daisuke N. Saito, Minyoung Jung, Sumiyoshi Arai, Yukiko Matsumura, Takashi X. Fujisawa, Kosuke Narita, Katsuaki Suzuki, Kenji J. Tsuchiya, Norio Mori, Taiichi Katayama, Makoto Sato…

    Citation: Molecular Autism 2016 7:19

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  13. Content type: Research

    Intellectual disability (ID), autism, and epilepsy share frequent yet variable comorbidities with one another. In order to better understand potential genetic divergence underlying this variable risk, we studi...

    Authors: Emily L. Casanova, Julia L. Sharp, Hrishikesh Chakraborty, Nahid Sultana Sumi and Manuel F. Casanova

    Citation: Molecular Autism 2016 7:18

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  14. Content type: Research

    Fragile X syndrome (FXS) is a single-gene disorder that is the most common heritable cause of intellectual disability and the most frequent monogenic cause of autism spectrum disorders (ASD). FXS is caused by ...

    Authors: Jantine A. C. Broek, Zhanmin Lin, H. Martijn de Gruiter, Heleen van ‘t Spijker, Elize D. Haasdijk, David Cox, Sureyya Ozcan, Gert W. A. van Cappellen, Adriaan B. Houtsmuller, Rob Willemsen, Chris I. de Zeeuw and Sabine Bahn

    Citation: Molecular Autism 2016 7:17

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  15. Content type: Research

    Autism spectrum disorders (ASDs) represent a heterogeneous group of disorders with a wide range of behavioral impairments including social and communication deficits. Apart from these core symptoms, a signific...

    Authors: Anwesha Banerjee, Jonathan A. Luong, Anthony Ho, Aeshah O. Saib and Jonathan E. Ploski

    Citation: Molecular Autism 2016 7:16

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  16. Content type: Short report

    Some previous research has suggested that testosterone prenatally contributes to gender differences in autistic traits, but little is known about the role of testosterone during early postnatal development (mi...

    Authors: Karson T. F. Kung, Mihaela Constantinescu, Wendy V. Browne, Rebecca M. Noorderhaven and Melissa Hines

    Citation: Molecular Autism 2016 7:15

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  17. Content type: Research

    Amygdala dysfunction is hypothesized to underlie the social deficits observed in autism spectrum disorders (ASD). However, the neurobiological basis of this hypothesis is underspecified because it is unknown w...

    Authors: Annika Rausch, Wei Zhang, Koen V. Haak, Maarten Mennes, Erno J. Hermans, Erik van Oort, Guido van Wingen, Christian F. Beckmann, Jan K. Buitelaar and Wouter B. Groen

    Citation: Molecular Autism 2016 7:13

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  18. Content type: Research

    The ability to follow gaze is an important prerequisite for joint attention, which is often compromised in children with autism spectrum disorder (ASD). The direction of both the head and eyes provides cues to...

    Authors: Emilia Thorup, Pär Nyström, Gustaf Gredebäck, Sven Bölte and Terje Falck-Ytter

    Citation: Molecular Autism 2016 7:12

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  19. Content type: Research

    Individuals with autism spectrum disorder (ASD) have been characterized by altered cerebral cortical structures; however, the field has yet to identify consistent markers and prior studies have included mostly...

    Authors: Daniel Y.-J. Yang, Danielle Beam, Kevin A. Pelphrey, Sebiha Abdullahi and Roger J. Jou

    Citation: Molecular Autism 2016 7:11

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  20. Content type: Research

    Autism spectrum conditions (autism) are diagnosed more frequently in boys than in girls. Females with autism may have been under-identified due to not only a male-biased understanding of autism but also female...

    Authors: Agnieszka Rynkiewicz, Björn Schuller, Erik Marchi, Stefano Piana, Antonio Camurri, Amandine Lassalle and Simon Baron-Cohen

    Citation: Molecular Autism 2016 7:10

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  21. Content type: Review

    Growing evidence points toward a critical role for early (prenatal) atypical neurodevelopmental processes in the aetiology of autism spectrum condition (ASC). One such process that could impact early neural de...

    Authors: Adam M. H. Young, Bhismadev Chakrabarti, David Roberts, Meng-Chuan Lai, John Suckling and Simon Baron-Cohen

    Citation: Molecular Autism 2016 7:9

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  22. Content type: Research

    Children with attention deficit/hyperactivity disorder (ADHD) often present with social difficulties, though the extent to which these clearly overlap with symptoms of autism spectrum disorder (ASD) is not wel...

    Authors: Rebecca Grzadzinski, Catherine Dick, Catherine Lord and Somer Bishop

    Citation: Molecular Autism 2016 7:7

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  23. Content type: Research

    Genetic, hormonal, and environmental factors contribute since infancy to sexual dimorphism in regional brain structures of subjects with typical development. However, the neuroanatomical differences between ma...

    Authors: Alessandra Retico, Alessia Giuliano, Raffaella Tancredi, Angela Cosenza, Fabio Apicella, Antonio Narzisi, Laura Biagi, Michela Tosetti, Filippo Muratori and Sara Calderoni

    Citation: Molecular Autism 2016 7:5

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  24. Content type: Research

    Atypical responsiveness to olfactory stimuli has been reported as the strongest predictor of social impairment in children with autism spectrum disorders (ASD). However, previous laboratory-based sensory psych...

    Authors: Hirokazu Kumazaki, Taro Muramatsu, Takashi X. Fujisawa, Masutomo Miyao, Eri Matsuura, Ken-ichi Okada, Hirotaka Kosaka, Akemi Tomoda and Masaru Mimura

    Citation: Molecular Autism 2016 7:6

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  25. Content type: Research

    As evidenced in the DSM-V, autism spectrum disorders (ASD) are often characterized by atypical sensory behavior (hyper- or hypo-reactivity), but very few studies have evaluated olfactory abilities in individua...

    Authors: Bruno Wicker, Elisabetta Monfardini and Jean-Pierre Royet

    Citation: Molecular Autism 2016 7:4

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  26. Content type: Research

    Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental disorders thought to have both genetic and environmental causes. It has been hypothesized that exposure...

    Authors: Jonna Maria Eriksson, Sebastian Lundström, Paul Lichtenstein, Susanne Bejerot and Elias Eriksson

    Citation: Molecular Autism 2016 7:8

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  27. Content type: Research

    Researchers have demonstrated that d-cycloserine (DCS) can enhance the effects of behavioral interventions in adults with anxiety and enhances prosocial behavior in animal models of autism spectrum disorders (ASD...

    Authors: Noha F. Minshawi, Logan K. Wink, Rebecca Shaffer, Martin H. Plawecki, David J. Posey, Hai Liu, Sarah Hurwitz, Christopher J. McDougle, Naomi B. Swiezy and Craig A. Erickson

    Citation: Molecular Autism 2016 7:2

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  28. Content type: Research

    Dysfunctions in the PI3K/mTOR pathway have gained a lot of attention in autism research. This was initially based on the discovery of several monogenic autism spectrum disorders with mutations or defects in PI...

    Authors: Ashwini C. Poopal, Lindsay M. Schroeder, Paul S. Horn, Gary J. Bassell and Christina Gross

    Citation: Molecular Autism 2016 7:3

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  29. Content type: Research

    Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders caused by the interaction between genetic vulnerability and environmental factors. MicroRNAs (miRNAs) are key posttranscriptional reg...

    Authors: Lam Son Nguyen, Marylin Lepleux, Mélanie Makhlouf, Christelle Martin, Julien Fregeac, Karine Siquier-Pernet, Anne Philippe, François Feron, Bruno Gepner, Claire Rougeulle, Yann Humeau and Laurence Colleaux

    Citation: Molecular Autism 2016 7:1

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  30. Content type: Research

    Findings of auditory abnormalities in children with autism spectrum disorder (ASD) include delayed superior temporal gyrus auditory responses, pre- and post-stimulus superior temporal gyrus (STG) auditory osci...

    Authors: J. Christopher Edgar, Charles L. Fisk IV, Jeffrey I. Berman, Darina Chudnovskaya, Song Liu, Juhi Pandey, John D. Herrington, Russell G. Port, Robert T. Schultz and Timothy P. L. Roberts

    Citation: Molecular Autism 2015 6:69

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  31. Content type: Research

    Recent research investigating the extreme male brain theory of autism spectrum disorders (ASD) has drawn attention to the possibility that autistic type social difficulties may be associated with high prenatal...

    Authors: Manuela Barona, Radha Kothari, David Skuse and Nadia Micali

    Citation: Molecular Autism 2015 6:68

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  32. Content type: Research

    Fragile X syndrome (FXS) is a neurodevelopmental disorder whose biochemical manifestations involve dysregulation of mGluR5-dependent pathways, which are widely modeled using cultured neurons. In vitro phenotyp...

    Authors: Daria Prilutsky, Alvin T. Kho, Nathan P. Palmer, Asha L. Bhakar, Niklas Smedemark-Margulies, Sek Won Kong, David M. Margulies, Mark F. Bear and Isaac S. Kohane

    Citation: Molecular Autism 2015 6:66

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  33. Content type: Research

    Recent brain imaging findings suggest that there are widely distributed abnormalities affecting the brain connectivity in individuals with autism spectrum disorder (ASD). Using graph theoretical analysis, it i...

    Authors: Ulrika Roine, Timo Roine, Juha Salmi, Taina Nieminen-von Wendt, Pekka Tani, Sami Leppämäki, Pertti Rintahaka, Karen Caeyenberghs, Alexander Leemans and Mikko Sams

    Citation: Molecular Autism 2015 6:65

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  34. Content type: Research

    Autism spectrum disorder (ASD) has been associated with autonomic atypicalities, although the nature of these differences remains largely unknown. Moreover, existing literature suggests large variability in au...

    Authors: Sakeena Panju, Jessica Brian, Annie Dupuis, Evdokia Anagnostou and Azadeh Kushki

    Citation: Molecular Autism 2015 6:64

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  35. Content type: Research

    Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impairment in social communication/interaction and inflexible/repetitive behavior. Several lines of evidence support g...

    Authors: Xin He, Stetson Thacker, Todd Romigh, Qi Yu, Thomas W. Frazier Jr and Charis Eng

    Citation: Molecular Autism 2015 6:63

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    The Erratum to this article has been published in Molecular Autism 2016 7:14

  36. Content type: Research

    Aggression is common in patients with autism spectrum disorders (ASD) along with the core symptoms of impairments in social communication and repetitive behavior. Risperidone, an atypical antipsychotic, is wid...

    Authors: Emma L. Burrows, Liliana Laskaris, Lynn Koyama, Leonid Churilov, Joel C. Bornstein, Elisa L. Hill-Yardin and Anthony J. Hannan

    Citation: Molecular Autism 2015 6:62

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  37. Content type: Research

    Individuals severely affected by autism spectrum disorder (ASD), including those with intellectual disability, expressive language impairment, and/or self-injurious behavior (SIB), are underrepresented in the ...

    Authors: Matthew Siegel, Kahsi A. Smith, Carla Mazefsky, Robin L. Gabriels, Craig Erickson, Desmond Kaplan, Eric M. Morrow, Logan Wink and Susan L. Santangelo

    Citation: Molecular Autism 2015 6:61

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  38. Content type: Research

    The Duchenne and Becker muscular dystrophies (DMD, BMD) show significant comorbid diagnosis for autism, and the genomic sequences encoding the proteins responsible for these diseases, the dystrophin and associ...

    Authors: Rubén Miranda, Flora Nagapin, Bruno Bozon, Serge Laroche, Thierry Aubin and Cyrille Vaillend

    Citation: Molecular Autism 2015 6:60

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  39. Content type: Research

    Previous studies have demonstrated aggregation of autistic traits in undiagnosed family members of children with autism spectrum disorder (ASD), which has significant implications for ASD risk in their offspri...

    Authors: Thomas W. Frazier, Eric A. Youngstrom, Antonio Y. Hardan, Stelios Georgiades, John N. Constantino and Charis Eng

    Citation: Molecular Autism 2015 6:58

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  40. Content type: Research

    Theory-of-mind (ToM), the ability to infer people’s thoughts and feelings, is a pivotal skill in effective social interactions. Individuals with autism spectrum disorders (ASD) have been found to have altered ...

    Authors: Rajesh K. Kana, Jose O. Maximo, Diane L. Williams, Timothy A. Keller, Sarah E. Schipul, Vladimir L. Cherkassky, Nancy J. Minshew and Marcel Adam Just

    Citation: Molecular Autism 2015 6:59

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  41. Content type: Research

    Platelets have been proven to be a useful cellular model to study some neuropathologies, due to the overlapping biological features between neurons and platelets as granule secreting cells. Altered platelet de...

    Authors: Nora Bijl, Chantal Thys, Christine Wittevrongel, Wouter De la Marche, Koenraad Devriendt, Hilde Peeters, Chris Van Geet and Kathleen Freson

    Citation: Molecular Autism 2015 6:57

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  42. Content type: Research

    RBFOX1 (also known as FOX1 or A2BP1) regulates alternative splicing of a variety of transcripts crucial for neuronal functions. Physiological significance of RBFOX1 during brain development is seemingly essent...

    Authors: Nanako Hamada, Hidenori Ito, Ikuko Iwamoto, Rika Morishita, Hidenori Tabata and Koh-ichi Nagata

    Citation: Molecular Autism 2015 6:56

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  43. Content type: Research

    Disruptive mutation in the CHD8 gene is one of the top genetic risk factors in autism spectrum disorders (ASDs). Previous analyses of genome-wide CHD8 occupancy and reduced expression of CHD8 by shRNA knockdown i...

    Authors: Ping Wang, Mingyan Lin, Erika Pedrosa, Anastasia Hrabovsky, Zheng Zhang, Wenjun Guo, Herbert M. Lachman and Deyou Zheng

    Citation: Molecular Autism 2015 6:55

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  44. Content type: Research

    Autism spectrum disorder (ASD) is characterized by atypical development of cortical and subcortical gray matter volume. Subcortical structural changes have been associated with restricted and repetitive behavi...

    Authors: Ian W. Eisenberg, Gregory L. Wallace, Lauren Kenworthy, Stephen J. Gotts and Alex Martin

    Citation: Molecular Autism 2015 6:54

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  45. Content type: Research

    Adolescent females with an autism spectrum disorder (ASD) are an understudied population, yet are also quite vulnerable, due to the increased complexities of social interaction and increased risk for internali...

    Authors: T. Rene Jamison and Jessica Oeth Schuttler

    Citation: Molecular Autism 2015 6:53

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