Skip to content

Advertisement

  • Erratum
  • Open Access

Erratum to: Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits

Molecular AutismBrain, Cognition and Behavior20167:14

https://doi.org/10.1186/s13229-016-0075-y

©  He et al. 2016

  • Published:

The original article was published in Molecular Autism 2015 6:63

Erratum

We have just noticed a minor error in Fig. 1a of our article [1]. The m3m4 mutation was described incorrectly as it improperly describes two Pten mutations, R233N and K269N. However, the confirmed sequence data on the m3m4 mutation indicates there are five nucleotide changes, as we have previously published [2], resulting in four amino acid changes: R233Q, R234Q, K265N, and K266Q. The fifth nucleotide change is a synonymous mutation, L264L. For greater clarity on the details of the nucleotide changes and the corresponding amino acid changes of the m3m4 mutation, they have been provided:
Fig. 1
Fig. 1

a. NLS-like region of Pten and the missense mutations created in the NLS-like region

Additionally, the included Fig. 1a now shows the correct amino acid changes. We apologize for any confusion caused by this error.

Notes

Declarations

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

(1)
Genomic Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, Mailstop NE-50, Cleveland, OH 44195, USA
(2)
Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA
(3)
HHMI Graduate Program, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA
(4)
Center for Autism, Pediatrics Institute, Cleveland Clinic, Cleveland, OH, USA
(5)
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA
(6)
Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA
(7)
Stanley Shalom Zielony Institute of Nursing Excellence, Cleveland Clinic, Cleveland, OH, USA
(8)
Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA
(9)
CASE Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA

Reference

  1. He X, Thacker S, Romigh T, Yu Q, Frazier Jr TW, Eng C. Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits. Mol Autism. 2015;6:63.View ArticlePubMedPubMed CentralGoogle Scholar
  2. Tilot AK, Gaugler MK, Yu Q, Romigh T, Yu W, Miller RH, et al. Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production. Hum Mol Genet. 2014;23(12): 3212–27. doi:10.1093/hmg/ddu031.

Copyright

© He et al. 2016

Advertisement

Molecular Autism

ISSN: 2040-2392