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Erratum to: Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits

Molecular Autism volume 7, Article number: 14 (2016) Cite this article

Erratum

We have just noticed a minor error in Fig. 1a of our article [1]. The m3m4 mutation was described incorrectly as it improperly describes two Pten mutations, R233N and K269N. However, the confirmed sequence data on the m3m4 mutation indicates there are five nucleotide changes, as we have previously published [2], resulting in four amino acid changes: R233Q, R234Q, K265N, and K266Q. The fifth nucleotide change is a synonymous mutation, L264L. For greater clarity on the details of the nucleotide changes and the corresponding amino acid changes of the m3m4 mutation, they have been provided:

Fig. 1
figure1

a. NLS-like region of Pten and the missense mutations created in the NLS-like region

Full size image

Additionally, the included Fig. 1a now shows the correct amino acid changes. We apologize for any confusion caused by this error.

Reference

  1. 1.

    He X, Thacker S, Romigh T, Yu Q, Frazier Jr TW, Eng C. Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits. Mol Autism. 2015;6:63.

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  2. 2.

    Tilot AK, Gaugler MK, Yu Q, Romigh T, Yu W, Miller RH, et al. Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production. Hum Mol Genet. 2014;23(12): 3212–27. doi:10.1093/hmg/ddu031.

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Affiliations

  1. Genomic Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, Mailstop NE-50, Cleveland, OH 44195, USA

    Xin He, Stetson Thacker, Todd Romigh, Qi Yu, Thomas W. Frazier Jr & Charis Eng

  2. Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA

    Xin He, Stetson Thacker, Todd Romigh, Qi Yu, Thomas W. Frazier Jr & Charis Eng

  3. HHMI Graduate Program, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA

    Stetson Thacker, Thomas W. Frazier Jr & Charis Eng

  4. Center for Autism, Pediatrics Institute, Cleveland Clinic, Cleveland, OH, USA

    Thomas W. Frazier Jr

  5. Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA

    Thomas W. Frazier Jr

  6. Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA

    Charis Eng

  7. Stanley Shalom Zielony Institute of Nursing Excellence, Cleveland Clinic, Cleveland, OH, USA

    Charis Eng

  8. Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA

    Charis Eng

  9. CASE Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA

    Charis Eng

Authors
  1. Xin He
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  2. Stetson Thacker
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  3. Todd Romigh
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  4. Qi Yu
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  5. Thomas W. Frazier Jr
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  6. Charis Eng
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Corresponding author

Correspondence to Charis Eng.

Additional information

The online version of the original article can be found under doi:10.1186/s13229-015-0056-6.

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He, X., Thacker, S., Romigh, T. et al. Erratum to: Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits. Molecular Autism 7, 14 (2016). https://doi.org/10.1186/s13229-016-0075-y

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Molecular Autism

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