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Table 1 Numbers of animals, neurons, dendrites, spines, and synapses examined in the morphological and EM analysis

From: Impaired synaptic function and hyperexcitability of the pyramidal neurons in the prefrontal cortex of autism-associated Shank3 mutant dogs

 

WT

Shank3 Het

Animals

3 males

2 males, 1 female

Neurons

9 (4, 3, 2)

13 (7, 3, 3)

Dendrites

55 (32, 13, 10)

69 (34, 18, 17)

Total spines

14,173 (5497, 3870, 4806)

8251 (3863, 2349, 2039)

  Thin

8869 (3373, 2334, 3162)

5412 (2500, 1462, 1450)

  Stubby

4133 (1600, 1179, 1354)

1740 (875, 620, 245)

  Mushroom

662 (281, 257, 124)

717 (341, 176, 200)

  Filopodia

509 (243, 100, 166)

382 (147, 91, 144)

Synapses

228 (94, 82, 52)

213 (57, 87, 69)

  1. Data show total counts for each category, the numbers in the parentheses correspond to three different animals