Delineating the autistic phenotype in children with neurofibromatosis type 1

Table 3 Current ADI-R and ADOS-2 domain and SRS-2 correlations with child characteristics

Child characteristics	ADI-R (N = 65)^b			ADOS-2 (N = 65)^b		SRS-2 (N = 68)^c
Child characteristics	Social	Comm	RRB	SA-CSS	RRB-CSS	Total T-score
Word Delay^a	.28	.40*	.13	.22	− .01	− .10
Phrase Delay^a	.31	.43**	.06	.32	− .09	− .15
Full-Scale IQ	− .03	− .17	.06	− .05	.01	− .11
Verbal Comprehension Index	− .16	− .27	.02	− .28	− .04	− .12
Visual Spatial Index	.05	.02	.11	.22	.09	.01
Fluid Reasoning Index	− .01	− .04	.12	.22	.19	− .09
Conners Inattention	.20	.20	.11	.14	.10	.42**
Conners Hyperactivity/Impulsivity	.36*	.28	.29	.05	.12	.48**
CBCL Anxiety Problems	.06	− .15	.09	− .15	.25	.34*
CBCL Affective Problems	.12	.05	.23	− .17	.04	.25
CBCL Oppositional Defiant Problems	.03	− .04	− .01	.02	.11	.36*
Social Risk	− .10	− .07	− .02	− .09	.11	.07

ADI-R Autism Diagnostic Interview-Revised, ADOS-2 Autism Diagnostic Observation Scale-Second Edition, CBCL
Child Behavior Checklist, Comm communication, Conners Conners-Third Edition or Conners ADHD DSM-IV Rating
Scale, CSS calibrated severity score, IQ intelligence quotient, RRB restricted/repetitive behaviours, SA Social Affect, SRS-2 Social Responsiveness Scale-Second Edition
^aADI-R lifetime scores used to calculate correlation coefficients, ^bN ranges between 62 and 65, ^cN ranges between 64 and 68
*p < .01, **p < .001

ISSN: 2040-2392