Table 2 Mean (95% CI) and proportion meeting cut-offs on ADI-R and ADOS-2 diagnostic algorithms and domains
From: Delineating the autistic phenotype in children with neurofibromatosis type 1
ADI-R (N = 65) | Mean (95% CI) | Met cut-off N (%) |  |  |  |  |
|---|---|---|---|---|---|---|
Social Interaction (Cut-off = 10) | 11.7 (9.8, 13.6) | 32 (49.2) |  |  |  |  |
Communication (Cut-off = 8) | 9.5 (8.0, 10.9) | 36 (55.4) |  |  |  |  |
RRB (Cut-off = 3) | 2.9 (2.4, 3.5) | 38 (58.5) |  |  |  |  |
Met criteria for all three algorithms | Â | 22 (33.8) | Â | Â | Â | Â |
| Â | Â | Evidence of autism symptoms based on CSS N (%) | ||||
|---|---|---|---|---|---|---|
ADOS-2 (N = 65) | Mean (95% CI) | Met AS cut-off N (%) | No/Minimal (1–2) | Low (3–4) | Moderate (5–7) | High (8–10) |
Overall Raw Score (AS Cut-off = 7/8) | 8.5 (7.4, 9.7) | 41 (63.1) |  |  |  |  |
Overall-CSS | 4.8 (4.2, 5.4) | Â | 12 (18.5) | 22 (33.8) | 20 (30.8) | 11 (16.9) |
Social Affect-CSS | 5.4 (4.8, 6.0) | Â | 8 (12.3) | 21 (32.3) | 21 (32.3) | 15 (23.1) |
RRB-CSS | 4.5 (3.8, 5.2) | Â | 21 (32.3) | N/A | 37 (56.9) | 7 (10.8) |