Table 1 Clinical and demographic characteristics of the individuals enrolled in the study
|  | ASD (N = 267) | Relatives (N = 370) | Controls (N = 155) | R2 | F | p value |
|---|---|---|---|---|---|---|
Age | 17.7 (12.9) | 38.0 (17.2) | 38.0 (14.9) | 0.3 | 139.4 |  < 0.001 |
Sex—male ratio (%, n) | 86%, 230 | 57%, 174 | 55%, 86 | 113.4* | – |  < 0.001 |
OCD (%, n) | 11.61%, 31 | 3.24%, 12 | 0.65%, 1 | 0.09 | – |  < 0.001 |
AD (%, n) | 14.23%, 38 | 10%, 37 | 1.94%, 3 | 0.06 | – |  < 0.001 |
TD (%, n) | 10.49%, 28 | 5.95%, 22 | 4.52%, 7 | 0.06 | – |  < 0.001 |
TS (%, n) | 1.49%, 4 | 0.27%, 1 | – | 0.08 | – | 0.15 |
NVIQ | 95.6 (23.2) | 113.3 (14.7) | 100.2 (19.8) | 0.1 | 32.0 |  < 0.001 |
SRS T-score | 72.2 (12.6) | 46.0 (8.5) | 44.4 (7.8) | 0.6 | 556.6 |  < 0.001 |
ADI—A | 16.4 (9.5) | – | – | – | – | – |
ADI—B | 11.5 (7.8) | – | – | – | – | – |
ADI—C | 4.9 (3.5) | – | – | – | – | – |
ADI—D | 2.6 (1.7) | – | – | – | – | – |
ADOS-CSS | 4.6 (2.1) | – | – | – | – | – |