Fig. 4

Age*SOR interaction effects on neural activation. A Clusters displaying (left) positive and (right) negative age*SOR linear interaction effects on the neural response to sensory stimulation. B Parameter estimates extracted from the significant interaction clusters in A) plotted against age by SOR group. High and low SOR groups (i.e., more and less severe SOR, respectively) were created with a median split within ASD participants for scatter plots solely to visualize the results displayed in A). C Regions showing a positive age²*SOR interaction effect on sensory-evoked neural activity. There were no significant negative age²*SOR interaction clusters. D Parameter estimates extracted from the clusters in C) were plotted against age²*SOR severity group as described in B) above. Mean absolute motion was regressed out of parameter estimates in the scatter plots in B) and D). PE Parameter estimates, SOR Sensory over-responsivity, OFC Orbitofrontal cortex, PG Parahippocampal gyrus, vmPFC Ventromedial prefrontal cortex, mPFC Medial prefrontal cortex, dlPFC Dorsolateral prefrontal cortex