Increased rates of chronic physical health conditions across all organ systems in autistic adolescents and adults

Table 5 Age stratified analysis of the likelihood of disorders of different organ systems, in a (top; 40 and under) and b (40 and over)

	Non-autistic participants (%)	Autistic participants (%)	Model 1		Model 2		Model 3		Model 4
			Odds ratio	FDR	Odds ratio	FDR	Odds ratio	FDR	Odds ratio	FDR
				p value		p value		p value		p value
(a) Under 41
Gastro	16.67	36.15	2.83	< 0.0001	3.20	< 0.0001	3.15	< 0.0001	3.26	< 0.0001
Neurological	16.66	26.26	1.92	< 0.0001	1.95	< 0.0001	1.86	< 0.0001	1.95	< 0.0001
Endocrine	14.63	21.40	1.59	0.0046	1.75	0.0029	1.65	0.0098	1.78	0.0030
Rheumatological	6.54	20.14	3.60	< 0.0001	3.89	< 0.0001	3.67	< 0.0001	3.83	< 0.0001
ENT	8.61	16.91	2.16	< 0.0001	2.21	4.1 × 10^–4	2.12	0.0011	2.10	0.0013
Ocular	31.67	39.59	1.41	0.0062	1.61	0.003	1.43	0.038	1.53	0.0087
Renal/hepatic	2.75	6.30	2.37	0.0062	2.39	0.020	2.33	0.030	–	–
Haematological	7.40	10.97	1.54	0.038	1.47	0.091	1.34	0.21	1.40	0.15
Dermatological	21.69	29.68	1.52	0.0038	1.58	0.0060	1.58	0.0098	1.56	0.0087
(b) 41 and over
Gastro	23.37	41.41	2.31	P < 0.0001	2.35	P < 0.0001	2.24	P < 0.0001	2.18	P < 0.0001
Neurological	20.28	33.64	1.99	P < 0.0001	2.30	P < 0.0001	2.24	P < 0.0001	2.18	P < 0.0001
Endocrine	19.07	19.89	1.05	0.73	1.26	0.20	1.14	0.49	1.21	0.32
Rheumatological	23.20	31.28	1.51	0.0029	1.70	0.0056	1.60	0.010	1.63	0.0097
ENT	10.65	18.63	1.92	5.0 × 10^–4	1.63	0.029	1.49	0.080	1.52	0.066
Ocular	40.03	50.09	1.50	0.0010	1.58	0.0056	1.58	0.011	1.61	0.0029
Renal/hepatic	4.81	10.49	2.32	7.5 × 10^–4	2.33	0.0056	2.18	0.012	2.14	0.013
Haematological	7.39	12.12	1.73	0.0086	1.84	0.0095	1.82	0.013	1.97	0.0086

ISSN: 2040-2392