Fig. 2

Transcriptome-wide level of deregulation in ASD brain and in vitro neurons correlates with L1 upregulation. A Total number of dysregulated genes (|z score|> 3) for all samples. In the case of the gene KO datasets, the average and standard deviation of the number of dysregulated genes among replicates has been plotted. B Correlation between the number of DE genes and the number of upregulated L1 in log2. C Number of DE genes (FDR < 0.05, |LogFoldChange|> 0.5) resulting from DEseq2 differential expression analysis