Fig. 4

ELSD/PASD treatment did not result in any lasting changes in the accelerating rotarod, marble burying, or hidden food assays. A, B Latency to fall in the accelerating rotarod assay of motor coordination and motor learning in control, ELSD, and PASD treated WT and Shank3^WT/ΔC heterozygous (HET) males (A) and females (B). No differences were observed (2-way ANOVA with Šídák’s multiple comparisons test). C, D Marbles buried by control, ELSD, and PASD treated males (C) and females (D). No differences were observed (unpaired t tests with Holm–Šídák correction). E, F Latency to find hidden food in the olfaction test. No differences were observed (unpaired t tests with Holm–Šídák correction). N = 8–12 per treatment/sex/genotype