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Table 1 Dup15q syndrome participant characteristics

From: Abnormal sleep physiology in children with 15q11.2-13.1 duplication (Dup15q) syndrome

Age (months) Gender Duplication type Epilepsy (active) Spike-wave index in sleep Medications (generic)
105 Female Isodicentric No < 35% Risperidone
Melatonin
23 Female Isodicentric No < 35% None
108 Female Isodicentric No < 35% None
18 Male Interstitial No < 35% None
35 Male Isodicentric No < 35% None
54 Male Isodicentric No < 35% None
68 Female Isodicentric Yes 45–50% Clobazam
Topiramate
137 Male Isodicentric Yes 40–45% Topiramate
73 Female Interstitial Yes < 35% Lamotrigine
Guanfacine
19 Male Isodicentric Yes 35–40% Vigabatrin
Prednisolone
57 Female Isodicentric Yes < 35% None
9 Female Isodicentric Yes < 35% Levetiracetam
Phenobarbital
55 Male Isodicentric Yes 65–70% None
108 Male Isodicentric Yes < 35% None
156 Male Isodicentric Yes 40–45% None
  1. This table describes the characteristics of participants in the Dup15q syndrome cohort. Details on age, gender, epilepsy status and medications were extracted from participant background questionnaires, and duplication type was extracted from participant genetic reports. The percentage of sleep occupied by spike-waves was reported as the spike-wave index in clinical EEG reports and was verified by a board-certified pediatric epileptologist
  2. Dosages were not available for all the medications listed, hence not included in the table