Neurite orientation dispersion and density imaging reveals white matter microstructural alterations in adults with autism

Table 5 Linear discriminant analysis classification with leave-one-out cross-validation results

Modality	Accuracy (%)	Sensitivity (%)	Specificity (%)	Positive predictive value (%)	Negative predictive value (%)
DTI
FA	71	69	72	72	69
MD	73	81	80	81	80
AD	65	58	72	68	62
RD	67	81	72	75	78
NODDI
NDI	82	81	84	84	81
ODI	55	58	52	56	54
ISOVF	82	77	88	87	79

AD, axial diffusivity; DTI, diffusion tensor imaging; FA, fractional anisotropy; ISOVF, isotropic volume fraction; MD, mean diffusivity; NDI, neurite density index; NODDI, neurite orientation dispersion and density imaging; ODI, orientation dispersion index; RD, radial diffusivity; TD, typically developing subjects

ISSN: 2040-2392