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Fig. 1 | Molecular Autism

Fig. 1

From: Neurite orientation dispersion and density imaging reveals white matter microstructural alterations in adults with autism

Fig. 1

Comparison of DTI (FA, MD, AD, and RD) and NODDI (NDI, ISOVF, and ODI) measures between autism and TD groups. Using TBSS analysis, significantly (family-wise error corrected P < 0.05) lower FA and NDI (blue–light blue voxels) and higher MD, RD, and ISOVF (red–yellow voxels) values were observed in the autism group than that in the TD. No significant differences were observed in AD and ODI values between the groups. The FA skeleton with FA of > 0.2 is shown in green. To aid visualization, results are thickened using the fill script implemented in FMRIB Software Library. AD, axial diffusivity; DTI, diffusion tensor imaging; FA, fractional anisotropy; ISOVF, intracellular volume fraction; L, left; MD, mean diffusivity; NDI, neurite density index; NODDI, neurite orientation dispersion and imaging; NS, not siginificant; ODI, orientation dispersion index; R, right; RD, radial diffusivity; TD, typically developing

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