|
ABC variable
|
Intervention (SF)a
|
Non-exposure (PL)
|
|---|
|
N
|
F-statistic
|
p value
|
N
|
F-statistic
|
p value
|
|---|
|
Total score
|
|
7 weeks
|
38
|
9.59
|
0.004
|
21
|
4.76
|
0.041
|
|
15 weeks
|
34
|
12.74
|
0.001
|
18
|
2.02
|
0.166
|
|
22 weeks
|
16
|
5.05
|
0.016
| | | |
|
30 weeks
|
12
|
2.22
|
0.156
| | | |
|
Sqrt lethargyb
|
|
7 weeks
|
38
|
1.55
|
0.221
|
21
|
2.94
|
0.102
|
|
15 weeks
|
34
|
4.75
|
0.016
|
18
|
1.68
|
0.218
|
|
22 weeks
|
16
|
4.20
|
0.028
| | | |
|
30 weeks
|
12
|
2.06
|
0.179
| | | |
|
Sqrt irritability
|
|
7 weeks
|
38
|
6.06
|
0.019
|
21
|
2.27
|
0.147
|
|
15 weeks
|
34
|
9.27
|
0.001
|
18
|
0.87
|
0.436
|
|
22 weeks
|
16
|
4.03
|
0.032
| | | |
|
30 weeks
|
12
|
2.06
|
0.179
| | | |
|
Sqrt stereotypy
|
|
7 weeks
|
38
|
4.85
|
0.034
|
21
|
1.74
|
0.202
|
|
15 weeks
|
34
|
6.06
|
0.006
|
18
|
1.72
|
0.210
|
|
22 weeks
|
16
|
1.22
|
0.343
| | | |
|
30 weeks
|
12
|
0.75
|
0.588
| | | |
|
Hyperactivity
|
|
7 weeks
|
38
|
9.62
|
0.004
|
21
|
10.15
|
0.005
|
|
15 weeks
|
34
|
9.95
|
< 0.001
|
18
|
4.68
|
0.025
|
|
22 weeks
|
16
|
5.36
|
0.013
| | | |
|
30 weeks
|
12
|
3.26
|
0.073
| | | |
|
Inappropriate speech
|
|
7 weeks
|
38
|
7.85
|
0.008
|
21
|
0.27
|
0.607
|
|
15 weeks
|
33
|
4.11
|
0.026
|
18
|
0.11
|
0.894
|
|
22 weeks
|
16
|
3.02
|
0.068
| | | |
|
30 weeks
|
12
|
1.95
|
0.196
| | | |
- Bold signifies p < 0.05
- MANOVA test for repeated measures
- aN for SF group at 7 and 15 weeks includes participants from the initial PL group while they were on SF at 22 and 30 weeks (their first 7 and 15 weeks of exposure)
- bSqrt: Square root transformations were conducted on these biomarkers to achieve a more normal distribution
