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Table 2 Summary of multivariable regression models of SRS and IQ in relation to clinical covariates (self-reported race, sex, maternal age, smoking status, insurance level of the mother, gestational age, birthweight Z-score, and inflammation of the placental chorion)

From: Evidence for the placenta-brain axis: multi-omic kernel aggregation predicts intellectual and social impairment in children born extremely preterm

Parameter SRS IQ
Estimate (SE) FDR-adjusted
P value
(Raw P value)
Estimate (SE) FDR-adjusted
P value
(Raw P value)
Race     
 Black 0.219 (0.13) 0.165 (0.091)  − 0.369 (0.13) 0.012 (0.004)
 Other 0.375 (0.19) 0.087 (0.043)  − 0.113 (0.18) 0.684 (0.533)
Sex     
 Male 0.119 (0.10) 0.342 (0.243)  − 0.288 (0.10) 0.012 (0.004)
 Maternal age  − 0.002 (0.01) 0.800 (0.800)  − 0.003 (0.01) 0.792 (0.748)
Smoking status     
 Yes 0.215 (0.17) 0.334 (0.204) 0.337 (0.17) 0.087 (0.043)
Mother’s insurance     
 Medicaid 0.454 (0.13) 0.002 (0.001)  − 0.453 (0.13) 0.003 (0.001)
 Gestational age  − 0.017 (0.01) 0.012 (0.002) 0.012 (0.01) 0.087 (0.043)
 Birthweight Z-score  − 0.060 (0.05) 0.342 (0.247) 0.179 (0.05) 0.003 (0.001)
 Placental inflammation  − 0.042 (0.11) 0.793 (0.705)  − 0.046 (0.11) 0.793 (0.677)