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Table 2 Summary of multivariable regression models of SRS and IQ in relation to clinical covariates (self-reported race, sex, maternal age, smoking status, insurance level of the mother, gestational age, birthweight Z-score, and inflammation of the placental chorion)

From: Evidence for the placenta-brain axis: multi-omic kernel aggregation predicts intellectual and social impairment in children born extremely preterm

Parameter

SRS

IQ

Estimate (SE)

FDR-adjusted

P value

(Raw P value)

Estimate (SE)

FDR-adjusted

P value

(Raw P value)

Race

    

 Black

0.219 (0.13)

0.165 (0.091)

 − 0.369 (0.13)

0.012 (0.004)

 Other

0.375 (0.19)

0.087 (0.043)

 − 0.113 (0.18)

0.684 (0.533)

Sex

    

 Male

0.119 (0.10)

0.342 (0.243)

 − 0.288 (0.10)

0.012 (0.004)

 Maternal age

 − 0.002 (0.01)

0.800 (0.800)

 − 0.003 (0.01)

0.792 (0.748)

Smoking status

    

 Yes

0.215 (0.17)

0.334 (0.204)

0.337 (0.17)

0.087 (0.043)

Mother’s insurance

    

 Medicaid

0.454 (0.13)

0.002 (0.001)

 − 0.453 (0.13)

0.003 (0.001)

 Gestational age

 − 0.017 (0.01)

0.012 (0.002)

0.012 (0.01)

0.087 (0.043)

 Birthweight Z-score

 − 0.060 (0.05)

0.342 (0.247)

0.179 (0.05)

0.003 (0.001)

 Placental inflammation

 − 0.042 (0.11)

0.793 (0.705)

 − 0.046 (0.11)

0.793 (0.677)