Imbalance of laminar-specific excitatory and inhibitory circuits of the orbitofrontal cortex in autism

Table 2 Further diagnosis of ASD cases

Subject ID	Score on autism diagnostic interview-revised
Subject ID	Social cutoff: 10	Communication cutoff (V): 8 cutoff (NV): 7	Restrictive and repetitive cutoff: 3	Early abnormal development cutoff: 1
4541^a	26	18 (V), 13 (NV)	6	5
5173^b	22	12 (NV)	2^a	5
6232	12	14 (V)	8	5
6677	26	22 (V)	12	5

Other diagnosed disorders included, a: schizophrenia; b: seizures
V verbal communication score, NV non-verbal communication score
^aScore was below cutoff threshold due to physical limitations and poor motor skills of donor. However, family members reported repetitive behaviors at a younger age. With this exception, which is not an unusual pattern in the behavioral domain, all donors had difficulties with communication, social behaviors, and atypical interests, consistent with a diagnosis of autism, and the ADI-R scores met and exceeded cutoffs for autism in each of these areas

ISSN: 2040-2392