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Table 1 Participant characteristics

From: Gray matter covariations and core symptoms of autism: the EU-AIMS Longitudinal European Autism Project

Demographic Autism, n = 347 TD, n = 252 t2 p value
Mean SD Mean SD
Age, yearsa 16.79 5.56 16.92 5.71 − 0.270 0.788
FSIQa,b 99.40 18.94 104.88 18.26 − 3.549 p < 0.001
 FSIQ ≥ 75 104.29 14.95 109.02 13.07 − 3.883 p < 0.001
 FSIQ < 75 66.61 5.44 63.69 9.20 1.399 0.172
  n % n %   
Sex, male/femalec 253/94 72.9/27.1 163/89 64.7/35.3 4.658 0.031
ADHD rating scaled, with/without ADHD 139/160 46.5/53.5 21/180 10.4/89.6 71.750 p < 0.001
Symptom profiles Mean SD Mean SD   
ADIe       
 Social interaction 16.80 6.66     
 Communication 13.50 5.62     
 RRB 4.32 2.67     
ADOSf       
 Social affect 6.04 2.59     
 RRB 4.73 2.78     
SRS T-scoreg 70.59 12.06 47.24 8.79   
RBSh 15.76 13.42 2.20 8.28   
SSPi 138.62 27.28 175.97 16.18   
  1. TD, typically developing; SD, standard deviation; FSIQ, full-scale intelligence quotient; ADHD, Attention Deficit Hyperactivity Disorder; ADI, Autism Diagnostic Interview-Revised; RRB, restricted, repetitive behaviors; ADOS, Autism Diagnostic Observational Schedule 2; SRS, Social Responsiveness Scale 2nd Edition; RBS, Repetitive Behavior Scale-Revised; SSP, Short Sensory Profile
  2. aStatistical differences were assessed by two-sample t test
  3. bIn Schedule A, B, and C (FSIQ ≥ 75), there are 302 participants with autism and 229 participants with TD. Schedule D (FSIQ < 75) comprised 45 participants with autism and 23 TD individuals
  4. cSex difference was examined by the chi-square test
  5. dADHD rating scores were available for 500 participants, including 299 individuals with autism and 201 TD individuals
  6. eADI scores were available for 332 participants
  7. fADOS scores were available for 339 participants. We considered calibrated severity scores
  8. gParent report SRS scores were available for 284 participants with autism and 135 TD individuals
  9. hRBS scores were available for 277 participants with autism and 133 TD individuals
  10. iSSP scores were available for 201 participants with autism and 115 TD individuals
  11. g,h,iIn all questionnaires, the scores of the autism group only were used in our study, and they are all parent-rated