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Table 6 Difference in MNS activation between ASD and TD in adult subgroup

From: Differential mirror neuron system (MNS) activation during action observation with and without social-emotional components in autism: a meta-analysis of neuroimaging studies

Brain regions with peak activation

Cluster breakdown

Anatomical region

L/R

Total number of voxels

MNI coordinates

SDM-Z

p (uncorrected)

Anatomical regions (Broadmann area)

ASD>TD

 Supplementary motor area

L

249

− 4,2,50

2.017

< 0.0005

Supplementary motor area (BA6, BA24)

 Inferior frontal gyrus (orbital part)

R

71

54, 26, − 4

1.826

~0.001

Inferior frontal gyrus, orbital part (BA45)

Inferior frontal gyrus, triangular part (BA45)

ASD<TD

 Precentral gyrus

L

708

− 42, 6, 48

− 2.565

~0.00001

Precentral gyrus (BA6)

Postcentral gyrus (BA4, BA6)

 Cerebellum, hemispheric lobule VI

R

742

18, − 72, − 28

− 1.987

< 0.001

Cerebellum, hemispheric lobule VI (BA18)

Cerebellum, crus I (BA19)