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Fig. 5 | Molecular Autism

Fig. 5

From: Targeting PPARα in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences

Fig. 5

VPA exposure differently affected sucrose preference in male and female rats. VPA-exposed male rats, independently from treatment, showed a lower preference for a 2% (w/v) sucrose solution. a Two-way ANOVA of sucrose preference expressed as percent volume of sucrose solution over total fluid volume (sucrose solution + water) drunk: VPA exposure: F1, 44 = 6.77, p = 0.0125; FBR administration: F1, 44 = 0.09, n.s.; interaction: F1, 44 = 0.045, n.s.). b In female rats, no significant effects of VPA exposure, FBR treatment, or their interaction were detected (VPA exposure: F1, 44 = 0.0044, n.s.; FBR administration: F1, 44 = 0.81, n.s.; interaction: F1, 44 = 0.89, n.s.). Values are expressed as mean ± SEM; n = 12. *p < 0.05 main effect of VPA exposure

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