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Fig. 4 | Molecular Autism

Fig. 4

From: Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors

Fig. 4

Up- and downregulated proteins and MeCP2-binding partners. a Heat map of all significant up- and b downregulated proteins with a p value ≤ 0.1 and ≥ 1.3-fold change between RTT and iCTR. The Z score of the difference between RTT and iCTR is given for each day with the corresponding cluster analysis and the GO terms for biological processes. c Network analysis of MeCP2-binding proteins identified in our data. The average log2 ratio RTT-iCTR over time is color coded for each protein over the time course of neuronal development. Edges are color coded according to the network as indicated

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