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Fig. 4 | Molecular Autism

Fig. 4

From: Loss of the neurodevelopmental disease-associated gene miR-146a impairs neural progenitor differentiation and causes learning and memory deficits

Fig. 4

Behavioral analyses of the Mir146a−/− mice.a 3-foot shock CFC performed in a 3-month-old Mir146a−/− mice (n = 16) and their control littermates (n = 15). Percent freezing was measured in CFC for each group during the training (as a control for the basal level of mouse freezing) and testing phases (to assess memory performances). b Novel object recognition test (NOR) performed in a 3-month-old Mir146a−/− mice (n = 16) and their control littermates (n = 15). Discrimination and preference indexes were measured for each group during the testing phase. c Object location memory (OLM) task performed in a 3-month-old Mir146a−/− mice (n = 16) and their control littermates (n = 15). Discrimination and preference indexes were measured for each group during the testing phase

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