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Table 7 Comparison of results between the main (all subjects) and additional analyses (ASD- discordant and concordant group, and the highest data quality group (High Q)). Significant B-estimates and q values are displayed in bold (q < 0.05) and estimates with a value of q < 0.1 are displayed as regular text. Results are FDR-corrected

From: Sex differences in brain structure: a twin study on restricted and repetitive behaviors in twin pairs with and without autism

Group (n)Regions associated with RRBI’s on the ADI-R C domain
Males
Main (88)
Nothing
Males
ASD Disc (28)
ASD Conc (6)
Bilateral Pallidum
Increased volume
(Left: B = 23.19, q = 0.096; right: B = 31.51, q = 0.096)
Males
High Q (34)
R. Supramarginal G.
Increased area
(B = 130.6, q = 0.035)
Increased Volume
(B = 842.22, q = 0.018)
L. Lateral orbital S.
Reduced area
(B = − 28.44, q = 0.035)
L. Anterior cingulate C.
Increased thickness
(B = 0.093, q = 0.001)
    
Females
Main (62)
R. Intraparietal S.
Increased thickness
(B = 0.037, q = 0.012)
Reduced area
(B = − 120.61, q = 0.072)
R. Orbital G.
Increased thickness
(B = 0.05, q = 0.056)
R. Inferior Frontal Orbital G.
Increased thickness
(B = 0.07, q = 0.065)
L. Superior Frontal G.
Reduced area
(B = − 130.44, q = 0.072)
R. Middle Frontal G.
Increased area
(B = 95.29, q = 0.072)
  
Females
ASD disc (12)
ASD Conc (6)
R. Intraparietal S.
Increased thickness
(B = 0.032, q = 0.013)
R. Orbital G.
Increased thickness B = 0.070, q = 0.016)
Increased volume
(B = 166.73, q = 0.059)
L. Lateral Orbital S.
Increased thickness
(B = 0.110, q = 0.002)
L. Superior Frontal G.
Increased thickness (B = 0.043, q = 0.003)
R. Postcentral G.
Increased thickness
(B = 0.039, q = 0.087)
L. Postcentral S.
Reduced volume
(B = − 208.12, q = 0.059)
 
Females
High Q (36)
Bi. Intraparietal S.
Increased thickness (Left: B = 0.045, q < 0.001; right: B = 0.053, q = 0.027)
L. Lateral orbital S.
Increased thickness (B = 0.094, q = 0.002)
L. Inferior frontal orbital G.
Increased thickness (B = 0.069, q = 0.022)
Increased volume
(B = 88.10, q = 0.059)
L. Superior frontal G.
Increased thickness (B = 0.059, q < 0.001)
Reduced area
(B = − 192.15, q = 0.010)
L. Middle frontal G.
Increased thickness (B = 0.036, q = 0.031)
R. Postcentral G.
Increased thickness (B = 0.038, q = 0.036)
Increased volume (B = 235.05, q = 0.053)
R. Postcentral S.
Increased thickness (B = 0.038, q < 0.001)
  1. L left, R right, Bi bilateral, G gyrus, S sulcus, C cortex