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Fig. 3 | Molecular Autism

Fig. 3

From: Integrated genetic and methylomic analyses identify shared biology between autism and autistic traits

Fig. 3

Permutation histogram of SNP-enrichment in top CpGs for three GWAS. The graphs present the results of the permutation analysis of the SNP enrichment. a Results of the autism GWAS. b Results of the SCDC GWAS. c Results of the Alzheimer’s GWAS. p value thresholds of the CpGs for enrichment are provided at the bottom of each column. Y-axis of each plot represents the frequency of the difference in mean p value of the mQTLs of CpGs below the threshold from the mean p value of the mQTLs of the CpGs above the threshold. X-axis represents the differences in the mean p value of the mQTLs of CpGs below the threshold from the mean p value of the mQTLs of the CpGs above the threshold. A higher difference in the means indicates a greater enrichment. Purple lines indicate the difference in mean of the non-permuted data point, i.e., the actual difference in mean

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Molecular Autism

ISSN: 2040-2392