Skip to main content

Table 5 Odds ratio and 95% confidence intervals for ASD according to PFAS in amniotic fluid

From: Autism spectrum disorders, endocrine disrupting compounds, and heavy metals in amniotic fluid: a case-control study

  Crude Adjusteda
n (cases/controls) OR (95% CI) p n (cases/controls) OR (95% CI) p FDR (qvalue)
PFOS (ng/mL) 37/51 0.460 (0.230, 0.921) 0.028 37/50 0.410 (0.174, 0.967) 0.042 0.437
PFOSA (ng/mL) 37/51 0.913 (0.797, 1.046) 0.189 37/50 0.918 (0.789, 1.069) 0.272 0.565
PFOA (ng/mL) 37/51 0.335 (0.044, 2.559) 0.292 37/50 0.164 (0.013, 2.126) 0.167 0.437
∑PFSA (ng/mL) 37/51 0.894 (0.777, 1.028) 0.115 37/50 0.900 (0.771, 1.049) 0.178 0.437
∑PFCA (ng/mL) 37/51 0.299 (0.041, 2.160) 0.232 37/50 0.150 (0.013, 1.760) 0.131 0.437
∑PFSA+∑PFCA (ng/mL) 37/51 0.894 (0.779, 1.025) 0.107 37/50 0.896 (0.770, 1.044) 0.158 0.437
  1. FDR (qvalue) false discovery rate. Italicized values indicate statistically significant (p < 0.05 and FDR qvalue < 0.25)
  2. aAdjusted for children’s birth year, children’s sex, mother age at delivery, father age at child birth, birth weight, gestational week at sampling, gestational age at birth, Apgar score, parity, and congenital malformation