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Fig. 6 | Molecular Autism

Fig. 6

From: CRISPR/Cas9-induced shank3b mutant zebrafish display autism-like behaviors

Fig. 6

shank3b deficiency altered the neurodevelopment in larvae. a–c Reduced RFP staining in shank3b−/− larvae compared to shank3b+/+ larvae (1 dpf, 2 dpf, and 3 dpf) using Huc: RFP transgene line zebrafish. The difference is the most prominent at 1 dpf. Scale bar, 100 μm. a’–c’ RT-qPCR results of RFP expressions from (ac) larvae. N = 8 for each group. Data are presented as mean ± SEM; *p < 0.05, ****p < 0.0001

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