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Fig. 2 | Molecular Autism

Fig. 2

From: Altered reward system reactivity for personalized circumscribed interests in autism

Fig. 2

Z-statistic activation maps depict reward system activation across the entire sample separately for the two high-level contrasts social reward > neutral outcome (hot colors) and interest reward > neutral outcome (cool colors). Both social reward and interest reward (versus neutral outcome) strongly activated a widespread reward system, comprising ventral and dorsal striatum, thalamus, amygdala, medial prefrontal areas (ACC, vmPFC) as well as clusters with orbitofrontal cortex (OFC) and anterior insula. Maps were thresholded using clusters determined by a voxel-level of p ≤ 0.001 and an FWE-corrected cluster-significance threshold of p ≤ 0.05. Color bars indicate Z-scores

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