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Table 1 Demographic and clinical features of the autistic children group

From: Advanced glycation endproducts, dityrosine and arginine transporter dysfunction in autism - a source of biomarkers for clinical diagnosis

No Age (years) Gender ADOS score CARS total score CARS activity level item score (hyperactivity) CARS body use item score (stereotypes) CARS total number of items with score ≥ 3 Autism severity level Cognitive/developmental impairment Onset pattern (1, early; 2, regressive; 3, mixed)† Probability of autism‡ from algorithm no.
1 2 3 4
1 6.0 m 22 41.0 2.0 3.0 9 Severe Severe 1 0.93 0.79 0.82 0.80
2 5.6 m 14 34.0 2.0 2.0 2 Mild Mild 1 1.00 0.71 0.99 0.77
3 5.5 m 18 40.5 2.5 3.5 9 Severe Moderate 1 1.00 0.86 1.00 0.29
4 5.4 f 17 31.5 2.0 2.0 1 Mild Mild 3 0.88 0.69 0.55 0.27
5 8.5 m 22 36.5 2.0 2.5 6 Mild Mild 3 0.98 0.64 1.00 0.88
6 8.7 m 19 44.5 3.0 3.0 11 Severe Moderate 2 1.00 0.69 1.00 0.74
7 6.8 m 19 36.5 2.5 2.0 7 Mild Normal IQ 1 1.00 0.63 1.00 0.91
8 5.5 f 15 41.5 2.5 2.0 9 Severe Borderline IQ 1 0.73 0.77 0.72 0.92
9 11.9 m 22 44.5 2.5 3.0 11 Severe Severe 2 0.20 0.91 0.34 0.45
10 9.2 f 15 47.5 3.5 3.0 13 Severe Moderate 1 0.84 0.88 0.94 0.36
11 12.0 m 20 39.0 3.0 3.5 8 Severe Severe 3 0.94 0.68 0.82 0.63
12 6.2 m 22 42.5 3.0 2.5 10 Severe Severe 1 1.00 0.69 1.00 0.98
13 6.7 m 21 40.5 2.5 3.0 9 Severe Severe 2 0.83 0.51 0.85 0.56
14 6.6 m 19 37.0 2.5 3.0 7 Severe Moderate 1 0.83 0.63 0.74 0.97
15 5.5 m 22 40.5 3.0 3.0 9 Severe Moderate 3 0.68 0.57 0.82 0.98
16 5.7 m 20 41.5 2.5 3.0 11 severe severe 1 0.98 0.81 0.98 0.81
17 7.8 m 21 46.0 3.5 4.0 11 Severe Severe 1 0.83 0.35 0.52 0.79
18 5.7 f 20 43.5 2.5 3.0 10 Severe Normal IQ 3 0.85 0.39 0.58 0.68
19 7.8 m 20 48.5 3.0 4.0 12 Severe Severe 2 0.95 0.58 0.93 0.57
20 6.8 m 19 42.0 3.0 3.0 9 Severe Moderate 2 0.67 0.61 0.54 0.77
21 9.6 m 19 39.5 3.0 3.0 7 Severe Severe 1 0.55 0.44 0.62 0.51
22 6.2 m 19 41.0 2.5 3.0 9 Severe Severe 3 0.81 0.32 0.78 0.73
23 8.3 m 16 35.0 2.5 2.0 3 Moderate Moderate 1 0.70 0.35 0.63 0.56
24 7.1 m 22 41.0 2.5 2.0 7 Severe Moderate 1 0.83 1.00 0.99 1.00
25 6.2 f 17 38.0 2.0 2.5 7 Severe Severe 1 0.28 0.82 0.15 0.79
26 10.3 f 21 33.5 2.0 2.0 4 Moderate Normal IQ 3 0.89 0.55 0.82 0.86
27 10.7 m 19 39.0 2.0 2.5 7 Moderate Normal IQ 1 0.89 0.60 0.97 0.52
28 6.5 m 17 39.0 3.0 2.5 6 Moderate Normal IQ 3 ND ND ND 0.76
29 8.0 m 22 44.0 2.5 3.0 11 Severe Moderate 1 ND ND ND 0.54
30 7.0 m 18 39.5 2.5 3.0 8 Moderate Normal IQ 1 ND ND ND 0.96
31 9.5 m 21 47.0 3.0 3.5 13 Severe Severe 1 ND ND ND 0.29
32 8.6 m 16 41.5 4.0 2.0 10 Severe Moderate 3 ND ND ND 0.33
33 10.9 m 18 35.0 2.0 3.0 3 Mild Normal IQ 1 ND ND ND 0.28
34 5.8 f 18 43.0 2.5 3.0 11 Severe Moderate 2 ND ND ND 0.30
35 5.3 f 17 39.5 2.5 2.5 6 Moderate Normal IQ 1 ND ND ND 0.62
36 5.3 f 17 41.0 2.5 2.5 7 Severe Normal IQ 1 ND ND ND 0.77
37 8.2 m 20 41.0 2.0 3.5 9 Severe Moderate 1 ND ND ND 0.58
38 11.1 m 13 34.0 2.0 1.5 2 Mild Normal IQ 3 ND ND ND 0.87
  1. †Onset pattern was defined according to Ozonoff et al. [18]
  2. ‡Probability the subject has autism estimated from diagnostic algorithms derived from experimental biomarker data—see Table 7