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Fig. 6 | Molecular Autism

Fig. 6

From: CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells

Fig. 6

Overlap in DEGs between CHD8 KO and BD neuronal cells. CHD8 KO DEGs from the current study (organoids) and our previous study (NPCs, neurons) [42] were compared with DEGs found in neurons derived from lithium responder and lithium non-responder patients with BD, as described in “Methods” section. The number in each panel shows the number of overlapping genes, which can be seen in Additional file 6: Table S5. The numbers in parentheses are the odds ratios

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Molecular Autism

ISSN: 2040-2392