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Fig. 1 | Molecular Autism

Fig. 1

From: CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in cerebral organoids derived from iPS cells

Fig. 1

Heat map and summary of GO terms and pathways. a The heat map shows differentially expressed genes between controls (CHD8 +/+) and heterozygous knockouts (CHD8 +/−). Enriched GO terms by DAVID (top) and pathways by IPA (bottom) for upregulated (b) and downregulated (c) genes in CHD8 +/− organoids. P values were corrected by the Benjamini method [147]

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Molecular Autism

ISSN: 2040-2392