| Limit of detection (pg/mL) | % outside limit of detection | Within df | Test statistics from mixed model | ||
---|---|---|---|---|---|---|
Group (1 df) | Age (2 df) | Age2 (2 df) | ||||
 |  |  | F(p) | F(p) | F(p) | |
Cytokines | ||||||
 IL-1α | 0.35 | 15 | 149 | 0.01 (.94) |  |  |
 IL-1RAa | 0.09 | 49 | 193 | 0.27 (.85) |  |  |
 IL-1βa | 0.03 | 49 | 193 | 0.23 (.85) |  |  |
 IL-2 | 0.03 | 29 | 117 | 0.46 (.81) |  |  |
 sIL-2RAa | 0.30 | 33 | 189 | 0.43 (.81) | 7.72 (.01) | 3.65 (.13) |
 IL-3a | 0.01 | 46 | 193 | 4.80 (.13) |  |  |
 IL-4 | 0.04 | 28 | 116 | 0.59 (.77) |  |  |
 IL-5 | 0.01 | 10 | 163 | 0.2 (.86) |  |  |
 IL-6a | 0.06 | 34 | 193 | 0.23 (.85) |  |  |
 IL-7 | 0.03 | 12 | 156 | 0.89 (.70) |  |  |
 IL-9 | 0.01 | 6 | 171 | 0.03 (.93) |  |  |
 IL-10 | 0.01 | 27 | 119 | 0.1 (.88) | 3.97 (.11) | 4.5 (.07) |
 IL-12p40 | 0.57 | 16 | 146 | 1.12 (.60) | 5.81 (.04) |  |
 IL-12p70 | 0.05 | 15 | 147 | 1.27 (.60) |  |  |
 IL-13a | 0.01 | 37 | 193 | 0.62 (.77) |  |  |
 IL-15a | 0.17 | 52 | 193 | 0.40 (.81) |  |  |
 IL-17 | 0.01 | 5 | 177 | 0.10 (.88) |  |  |
 IFNα2 | 0.12 | 5 | 174 | 0.79 (.73) |  |  |
 IFNγ | 0.04 | 2 | 186 | 0.02 (.93) |  |  |
 TNFα | na | 0 | 190 | 0.02 (.93) | 13.10 (<.001) |  |
 TNFβ | 0.02 | 27 | 123 | 0.04 (.93) |  |  |
 TGFα | 0.02 | 12 | 153 | 1.12 (.60) |  |  |
Growth factors | ||||||
 EGF | 2.70 | 7 | 170 | 8.64 (.04) |  |  |
 G-CSF | 1.65 | 1 | 186 | 0.10 (.88) | 3.99 (.11) |  |
 GM-CSF | 1.85 | 2 | 186 | 0.36 (.81) |  |  |
 VEGF | 3.36 | 3 | 185 | 2.26 (.43) |  |  |
 FGF-2 | 4.08 | 8 | 166 | 0.02 (.93) |  |  |
 FLT-3La | 0.04 | 57 | 193 | 1.19 (.60) |  |  |
 sCD40La | 1 671 700 | 53 | 193 | 15.0 (<.001) |  |  |
Chemokines | ||||||
 CCL2 (MCP-1) | na | 0 | 192 | 2.04 (.44) |  |  |
 CCL3 (MIP-1α) | 0.03 | 8 | 169 | 1.59 (.53) |  |  |
 CCL4 (MIP-1β) | 2.9 | 1 | 191 | 0.15 (.88) |  |  |
 CCL7 (MCP-3) | 0.73 | 21 | 132 | 0.59 (.77) |  |  |
 CCL11 (EOTAXIN) | 17.06 | 1 | 188 | 0.01 (.94) |  |  |
 CCL22 (MDC) | na | 0 | 190 | 4.73 (.13) | 7.92 (.01) |  |
 CXCL1 (GRO) | na | 0 | 193 | 1.65 (.53) |  |  |
 CXCL8 (IL-8) | na | 0 | 189 | 0.12 (.88) | 1.63 (.53) | 5.18 (.07) |
 CXCL10 (IP-10) | na | 0 | 192 | 2.59 (.42) |  |  |
 CX3CL1 (FRACTALKINE) | 2.1 | 26 | 119 | 0.02 (.93) |  |  |