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Table 2 Group results for psychiatric measurements

From: 22q11.2 duplication syndrome: elevated rate of autism spectrum disorder and need for medical screening

  SCQ SRS Vineland-II CASI-4R composite totals
  Total Total Communication Daily Living Socialization Composite ADHD ASD Schizo-affective Behavior regulation Depressive Anxiety
ASD             
 mean 21.5cd 76.6cd 83.9d 82.3d 74.0bcd 78.0bcd 13.7d 13.2cd 3.3d 4.8d 2.3d 4.4d
 SD 5.3 15.1 14.5 13.5 12.4 11.6 4.1 6.3 1.9 3.4 2.6 2.9
22q11.2DupS             
 mean 15.8d 69.8d 90.6d 93.5d 90.2ad 88.8ad 12.9d 8.3d 2.8 4.3 1.8d 3.8d
 SD 10.9 19.8 17.8 21.6 21.0 19.1 5.9 8.2 1.6 3.8 2.1 3.3
22q11.2DS             
 mean 11.3ad 66.6ad 89.8d 88.1d 90.2ad 87.0ad 12.4d 6.0ad 2.3d 4.6d 2.2d 4.6d
 SD 7.5 14.9 18.3 15.1 16.8 16.1 5.4 4.9 1.3 2.7 2.8 2.7
TDC             
 mean 1.7abc 41.9abc 113.1abc 110.8abc 114.0abc 113.1abc 3.9abc 0.3abc 0.2ac 1.9ac 0.3abc 0.9abc
 SD 1.8 5.4 12.8 12.8 12.7 12.4 33.6 0.7 0.3 2.0 0.6 1.2
  1. Measures: SCQ: Raw scores reported. Scores above 15 are strongly suggestive of ASD. SRS: Scores reported in T-scores with mean 50 and SD 10. Scores below 60 considered in normal range. CASI-4R: Total raw score for each symptom domain (created by averaging together related subdomains; see Supplemental materials for individual subscale mean scores). Vineland-II: Standard scores (mean 100 and SD 15); scores above 90 considered in the average range. Significantly different (p < 0.05) scores between groups on each measure are denoted by the following conventions:
  2. aThis value is significantly different from the ASD group’s value
  3. bThis value is significantly different from the 22q11.2DupS group’s value
  4. cThis value is significantly different from the 22q11.2DS group’s value
  5. dThis value is significantly different from the TDC group’s value
  6. Abbreviations: ADHD attention-deficit/hyperactivity disorder, ASD autism spectrum disorder, CASI-4R Child and Adolescent Symptom Inventory-4R, SCQ Social Communication Questionnaire, SRS Social Responsiveness Scale, TDC typically developing controls, Vineland-II Vineland Adaptive Behavior Scales-II