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Fig. 8 | Molecular Autism

Fig. 8

From: CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment

Fig. 8

Comparison of DEGs from CHD8 +/− and DEGs from brain ASD organoids [76]. Venn diagrams of DEGs from CHD8 +/− NPCs (a) or neurons (b) and DEGs from brain organoids. The number in each section represents genes that are also expressed in our samples. Top-enriched GO terms for overlapped genes between DEGs from CHD8 +/− NPCs (c) or neurons (d) and DEGs from brain organoids referred to as TD11 and TD31

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