Levels of expression of BDNF
(A) and its receptor gene NTRK2
(B). Gene expression was measured in laser captured BA24 pyramidal neurons and separately in surrounding astrocytes of typically developing control donors (open symbols) and ASD donors (closed symbols). Gene expression levels are normalized to the averaged levels of expression of references genes (GAPDH and RNA18S1). Mean values are noted by horizontal lines, and statistical significance (uncorrected for the number of comparisons) is noted above the data points. See Table 2 for statistical results following correction for the number of comparisons. BDNF, brain-derived neurotrophic factor.