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Table 4 Correlation of RORA and target gene expression in the cerebellum of age-matched females and males

From: Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism

A2BP1 vs. RORA

Females

Males

Group (no. of samples)

F_BB (4)

F_0-18 (5)

F >19 (3)

M_BB (3)

M_0-18 (6)

M >19 (3)

Correlation coefficient

0.96

0.95

0.82

1.00

0.64

-0.36

P val (2-tailed)

0.04

0.01

0.39

0.05

0.17

0.76

R2

0.93

0.91

0.67

0.99

0.41

0.14

ITPR1 vs. RORA

Females

Males

Group (no. of samples)

F_BB (4)

F_0-18 (5)

F > 19 (3)

M_BB (3)

M_0-18 (6)

M > 19 (3)

Correlation coefficient

0.98

0.95

0.98

0.71

0.89

0.96

P-val (2-tailed)

0.02

0.02

0.14

0.49

0.02

0.17

R2

0.96

0.89

0.95

0.52

0.79

0.93

NLGN1 vs. RORA

Females

Males

Group (no. of samples)

F_BB (4)

F_0-18 (5)

F > 19 (3)

M_BB (3)

M_0-18 (6)

M > 19 (3)

Correlation coefficient

0.99

0.99

0.99

0.90

0.42

0.41

P-val (2-tailed)

0.01

0.001

0.07

0.28

0.40

0.73

R2

0.97

0.98

0.99

0.83

0.18

0.17

  1. The correlation coefficients, P values, and R2 values are shown for RORA expression and that of A2BP1, ITPR1, and NLGN1 across each of the three developmental periods.