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Table 1 Fractional anisotropy (FA) values in individuals with Asperger syndrome (AS) and controls in the white matter (WM) tracts reconstructed with tractography

From: Constrained spherical deconvolution-based tractography and tract-based spatial statistics show abnormal microstructural organization in Asperger syndrome

WM a tract FA a (AS a subjects) b FA a (controls) b Pvalue c Corrected Pvalue c
ATR a L 0.3416 ± 0.0381 0.3335 ± 0.0330 0.2629 3.418
ATR a R 0.3511 ± 0.0399 0.3453 ± 0.0332 0.3330 4.329
SCC a 0.4521 ± 0.0225 0.4401 ± 0.0553 0.1995 2.593
CST a L 0.4957 ± 0.0254 0.4848 ± 0.0405 0.1757 2.284
CST a R 0.4915 ± 0.0278 0.4713 ± 0.0420 0.05339 0.6941
IFO a L 0.4381 ± 0.0336 0.4129 ± 0.0523 0.05162 0.6710
IFO a R 0.4365 ± 0.0261 0.4112 ± 0.0342 0.01095 0.1423
ILF a L 0.3864 ± 0.0277 0.3521 ± 0.0358 0.002026 0.02633
ILF a R 0.3697 ± 0.0258 0.3511 ± 0.0380 0.05233 0.6803
SLF a L 0.4266 ± 0.0154 0.3978 ± 0.0433 0.006523 0.08480
SLF a R 0.3899 ± 0.0255 0.3620 ± 0.0434 0.01405 0.1826
UNC a L 0.3426 ± 0.0368 0.3109 ± 0.0424 0.01470 0.1911
UNC a R 0.3353 ± 0.0373 0.3143 ± 0.0408 0.06743 0.8766
  1. aFA, fractional anisotropy; AS, Asperger syndrome; WM, white matter; ATR, anterior thalamic radiation; SCC, splenium of corpus callosum; CST, corticospinal tract; IFO, inferior fronto-occipital fasciculus; ILF, inferior longitudinal fasciculus; SLF, superior longitudinal fasciculus; UNC, uncinate fasciculus.
  2. bMean and standard deviations are presented for both groups.
  3. cBoth uncorrected and Bonferroni-corrected P values from two-sample t-tests are presented. A significant P value (corrected P <0.05) is highlighted in bold.