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Table 4 Summary of significant sex-diagnosis interactions of serum molecules measured by LC-MS E profiling

From: Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome

     Males Females
Code Protein Interaction FDR Ratio P-value Ratio P-value
RGPD4 RANBP2-like and GRIP domain containing 5 0.015 0.723 0.89 0.016 1.07 0.893
ARMC3 Armadillo repeat containing 3 0.002 0.291 0.88 0.183 1.29 0.001
PTPA PP 2A activator, reg subunit 4 0.038 0.723 0.97 0.681 1.23 0.001
TLE1 Transducin-like enhancer of split 1 0.049 0.723 0.90 0.394 1.22 0.026
CLC4K CD207 molecule, langerin 0.017 0.723 0.96 0.720 1.20 <0.001
GLCE Glucuronic acid epimerase 0.017 0.723 0.88 0.231 1.19 0.018
APOC2 Apolipoprotein C2 0.005 0.522 0.92 0.254 1.19 0.001
ZC3HE Zinc finger CCCH-type containing 14 0.039 0.723 0.97 0.383 1.16 0.020
FETUB Fetuin B 0.035 0.723 0.96 0.572 1.15 0.004
RN149 Ring finger protein 149 0.044 0.723 1.02 0.588 1.14 0.042
TRIPB Thyroid hormone receptor interactor 11 0.012 0.723 0.94 0.610 1.13 0.027
APOE Apolipoprotein E 0.030 0.723 0.99 0.851 1.11 <0.001
MRRP1 RNA G9 methyltransferase domain cont 1 0.044 0.723 1.06 0.592 0.78 0.035
  1. Indicated are the P-values and FDR (false discovery rate) of the interactions and the separate ratio (AS/control; calculated using geometric means) changes with P-values in males in females. Values in bold font indicate significant differences between AS and typical individuals by sex.
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Molecular Autism

ISSN: 2040-2392