Uncovering steroidopathy in women with autism: a latent class analysis

Table 5 Class prevalences and class-dependent conditional probabilities for conditions and symptoms relating to steroids

	Latent class membership
	Steroidopathic	Typical
ASC	48%	52%
Control	25%	75%
Posterior probabilities	Steroidopathic	Typical
Posterior probabilities	Conditional probability (95 % CI)	Conditional probability (95 % CI)
Delayed puberty	0.01 (0.00-0.03)	0.01 (0.00-0.02)
Periods after 16 years	0.07 (0.04-0.11)	0.05 (0.03-0.06)
Periods before 10 years	0.12 (0.08-0.17)	0.03 (0.01-0.06)
Precocious puberty	0.05 (0.02-0.08)	0.00 (0.00-0.00)
Early growth spurt	0.26 (0.20-0.33)	0.10 (0.07-0.14)
PCOS (ASC/control)	0.24 (0.16-0.33)/0.47 (0.35-0.64)	0.00 (0.00-0.00)
Hirsutism	0.40 (0.32-0.48)	0.04 (0.02-0.07)
Irregular menstrual cycle	0.72 (0.63-0.80)	0.22 (0.18-0.27)
Painful periods	0.61 (0.54-0.68)	0.16 (0.11-0.21)
Acne	0.22 (0.17-0.28)	0.11 (0.08-0.15)
Excessive menstrual bleeding	0.56 (0.48-0.63)	0.10 (0.05-0.15)

Percentages of the ASC and control groups assigned to the steroidopathic and typical latent classes (top) and conditional probabilities for Testosterone-related Medical Questionnaire items by latent class (bottom). Bootstrapped (500 starts) 95% confidence intervals of parameter estimates in brackets. ASC, autism spectrum conditions; PCOS, polycystic ovary syndrome.

ISSN: 2040-2392