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Table 5 Class prevalences and class-dependent conditional probabilities for conditions and symptoms relating to steroids

From: Uncovering steroidopathy in women with autism: a latent class analysis

  Latent class membership
  Steroidopathic Typical
ASC 48% 52%
Control 25% 75%
Posterior probabilities Steroidopathic Typical
Conditional probability (95 % CI) Conditional probability (95 % CI)
Delayed puberty 0.01 (0.00-0.03) 0.01 (0.00-0.02)
Periods after 16 years 0.07 (0.04-0.11) 0.05 (0.03-0.06)
Periods before 10 years 0.12 (0.08-0.17) 0.03 (0.01-0.06)
Precocious puberty 0.05 (0.02-0.08) 0.00 (0.00-0.00)
Early growth spurt 0.26 (0.20-0.33) 0.10 (0.07-0.14)
PCOS (ASC/control) 0.24 (0.16-0.33)/0.47 (0.35-0.64) 0.00 (0.00-0.00)
Hirsutism 0.40 (0.32-0.48) 0.04 (0.02-0.07)
Irregular menstrual cycle 0.72 (0.63-0.80) 0.22 (0.18-0.27)
Painful periods 0.61 (0.54-0.68) 0.16 (0.11-0.21)
Acne 0.22 (0.17-0.28) 0.11 (0.08-0.15)
Excessive menstrual bleeding 0.56 (0.48-0.63) 0.10 (0.05-0.15)
  1. Percentages of the ASC and control groups assigned to the steroidopathic and typical latent classes (top) and conditional probabilities for Testosterone-related Medical Questionnaire items by latent class (bottom). Bootstrapped (500 starts) 95% confidence intervals of parameter estimates in brackets. ASC, autism spectrum conditions; PCOS, polycystic ovary syndrome.