Molecular Autism

Table 2 Relationships between startle measures and T-scores on subscales of Social Responsiveness Scale (SRS)

From: Hyperreactivity to weak acoustic stimuli and prolonged acoustic startle latency in children with autism spectrum disorders

SRS scores		PSL	Startle response
SRS scores		PSL	ASR65	ASR70	ASR75	ASR80	ASR85	ASR90	ASR95	ASR100	ASR105	ASR110
Social awareness	rho	0.38*	0.38*	0.28	0.34*	0.42**	0.38*	0.29	0.21	0.13	−0.03	−0.02
Social awareness	P	0.016	0.015	0.083	0.031	0.007	0.015	0.071	0.183	0.437	0.855	0.910
Social cognition	rho	0.38*	0.29	0.37*	0.22	0.45**	0.50**	0.42**	0.38*	0.27	0.17	0.22
Social cognition	P	0.018	0.072	0.020	0.167	0.004	0.001	0.008	0.016	0.095	0.290	0.180
Social communication	rho	0.30	0.28	0.30	0.30	0.38*	0.42**	0.35*	0.31	0.19	0.08	0.15
Social communication	P	0.064	0.081	0.057	0.059	0.015	0.008	0.025	0.055	0.243	0.627	0.355
Social motivation	rho	0.34*	0.27	0.18	0.13	0.13	0.10	0.05	−0.05	−0.06	0.06	0.14
Social motivation	P	0.033	0.093	0.261	0.426	0.417	0.532	0.774	0.760	0.704	0.699	0.386
Autistic mannerisms	rho	0.42**	0.37*	0.41**	0.41**	0.48**	0.53**	0.31	0.21	0.10	−0.07	0.01
Autistic mannerisms	P	0.008	0.019	0.008	0.009	0.002	0.000	0.051	0.197	0.522	0.677	0.936

ASR65, ASR70, ASR75, ASR80, ASR85, ASR90, ASR95, ASR100, ASR105 and ASR110 are designated as the average startle eyeblink magnitude at stimulus intensities of 65, 70, 75, 80, 85, 90, 95, 100, 105 and 110 dB, respectively. n = 40 (ASD, n = 12; TD, n = 28). Spearman’s rank order correlation; *P <0.05; **P <0.01. ASD, autism spectrum disorders; ASR, acoustic startle reflex; PSL, average peak startle latency of acoustic startle reflex; SRS, Social Responsiveness Scale; TD, typical development.

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ISSN: 2040-2392

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