ASD_NTCV vs. TD. Unsupervised hierarchical clustering (A) and PCA (B) of the 169 exons predicted to display DAS/DEU with FDR P <0.05 in ASD_NTCV vs. TD analysis. The heatmap in 1A represents adjusted exon expression level (high=red, low=green) of the exons predicted to have DAS/DEU. TD subjects denoted in blue; ASD_NTCV subjects - in orange. The PCA plot in 1B shows separation of the ASD_NTCV (orange spheres) from the TD (blue spheres) subjects. The ellipsoids are drawn at 2 standard deviations around the group centroids.