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Table 2 Two-by-two mixed model ANOVA (group by reward type) for the contrast correct cue > baseline

From: Social and monetary reward processing in autism spectrum disorders

 

Cluster size (voxels)

F (Peak)

MNI co-ordinates (x,y,z)

BA and probability (%) (if available)

Main effect of reward anticipation (MID > SID):

Frontal

    

Right middle frontal gyrusa

64

27.63

44, -6, 58

6 (40%)

Left inferior frontal gyrus p. orbitalisa,b

242

23.95

−36, 34, -6

47

Left SMA

60

23.41

0, 10, 64

6 (40%)

Left inferior frontal gyrus p. triangularis

33

17.45

−44, 34, 14

45 (50%)

Right inferior frontal gyrus p. orbitalis

31

17.05

42, 26, -10

47

Temporal

    

Right superior temporal gyrus

43

23.42

56, -26, -2

21

Left middle temporal gyrus

52

19.33

−50, -58, -2

37

Left middle temporal gyrus

12

14.44

−56, -24, -12

20

Left inferior temporal gyrus

14

15.95

−34, -6, -23

20

Parietal

    

Left postcentral gyrusa

90

18.8

−46, -24, 48

2 (50%)

Right precuneus

51

17.99

8, -52, 44

7

Left inferior parietal lobule

29

15.16

−28, -50, 44

SPL 7PC (10%)

Right precentral gyrus

13

15.95

14, -28, 64

4a (50%)

Occipital

    

Left superior occipital gyrus

33

16.55

−20, -66, 38

SPL 7a (10%)

Right superior occipital gyrus

19

18.31

24, -74, 44

SPL 7P (10%)

Right middle occipital gyrusa

2951

33.03

36, -90, 6

17

Left middle occipital gyrus

484

24.21

−32, -90, 12

18 (10%)

Subcortical

    

Left nucleus accumbensb

228

30.25

−10, 2, 0

NA

Right nucleus accumbensb

199

27.38

8, 10, 0

NA

Left amygdala

14

15.95

−34, -6, -28

Amyg (LB) 40%

Cerebellum

    

Right lobule VIIa crus I

49

21.91

32, -76, -30

90%

Right lobule VIIa crus II

10

17.01

8, -86, -38

74%

Left lobule VI

36

21.53

−34, -46, -24

20%

Left VIIa crus 1

32

19.71

−24, -82, -32

99%

Group by reward type interaction:

Frontal

    

Left anterior cingulate

38

16.26

−6, 8, 30

24

Parietal

    

Left inferior parietal lobule

26

16.42

−36, -44, 46

40; hIP3 (40%)

  1. Results are reported at an uncorrected level of P <0.001 (extent threshold 10 voxels).
  2. aRegions surviving correction for multiple comparisons (FWE P <0.05) at the whole-brain cluster or peak level.
  3. bUsing anatomical small volume correction in a priori regions.