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Table 1 Demographic data for people with autism and healthy controlsa

From: Dysregulation of fragile X mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study

Case Dx Sex Age PMI, hours Ethnicity Medication History Cause of Death Seizure MR
4670 Control M 4 17 Caucasian None Commotio Cordis No No
1674 Control M 8 36 Caucasian None Drowning No No
4787 Control M 12 15 African American Montelukast, Albuteral, Prednisone, Loratadine Asthma No No
1823 Control M 15 18 Caucasian None MVA No No
6396 Control M 18 19.83 Unknown None Unknown No No
1846 Control F 20 9 Caucasian None MVA No No
6316 Control F 32 28.92 Unknown None Unknown No No
1169 Control M 33 27 African American Metoclopramide, Loratadine Dilated Cardiomyopathy (morbid obesity) No No
1376 Control M 37 12 African American None ASCVD No No
6420 Control M 41 30.4 Unknown None Heart Attack No No
7002 Autism F 5 32.73 Asian None Drowning No No
5569 Autism M 5 39 Caucasian None Drowning No No
1174 Autism F 7 14 Caucasian None Seizure disorder Yes No
5666 Autism M 8 22.16 Caucasian None Cancer Yes No
4231 Autism M 8 12 African American Olanzapine, Galantamine Drowning No Yes
4925 Autism M 9 27 Caucasian Clonidine, Sodium valproate, Phenytoin, Lamotrigine, Methylphenidate, Carbamazepine Seizure disorder Yes No
4899 Autism M 14 9 Caucasian None Drowning No No
6184 Autism F 18 6.75 Caucasian None Seizure disorder Yes No
5144 Autism M 20 23.66 Caucasian Erythromycin gel, Minocycline MVA No Yes
1638 Autism F 20 50 Caucasian None Seizure disorder Yes Yes
6337 Autism M 22 25 Caucasian Aripiprazole, Lamotrigine, Zonisamide Aspiration Yes No
6994 Autism M 29 43.25 Caucasian Fexofenadine, Ziprasidone HCl, Carbamazepine Seizure (suspected) Yes No
6640 Autism F 29 17.83 Caucasian Fluvoxamine Seizure disorder Yes No
6677 Autism M 30 16.06 Caucasian None Heart Failure (congestive) No No
5173 Autism M 30 20.33 Caucasian Cisapride, Clorazepate, Sodium valproate, Phenytoin, Folic Acid, Primidone, Phenobarbital, Omeprazole, Cisapride, Metoclopramide Gastrointestinal bleeding Yes No
5027 Autism M 37 26 African American None Obstruction of bowel due to adhesion No No
6401 Autism M 39 13.95 Caucasian None Cardiac Tamonade No No
5562 Autism M 39 22.75 Caucasian None Sudden unexpected death Yes No
6469 Autism F 49 16.33 Caucasian Wafarin, Venlafaxine, Erythromycin, Lansoprazole, Risperidone, Metformin, Gabapentin, Propranolol, Levothyroxine Pulmonary Arrest No Yes
4498 Autism M 56 19.48 Caucasian Benztropine mesylate, Haloperidol, Lithium, Chlorpromazine, Alprazolam Anoxic encephalopathy Yes No
Children Control Autistic Change P value Cohen's d     
Age ± SD (years) 11.4 ± 5.55 9.25 ± 4.53 ↓18.9% ns --     
PMI ± SD (years) 21.2 ± 8.47 18.6 ± 9.47 ↓12.3% ns --     
Gender 5M 5M:3F -- -- --     
Adults Control Autistic Change P value Cohen's d     
Age ± SD (years) 32.6 ± 7.89 33.3 ± 11.2 ↑2.1% ns --     
PMI ± SD (years) 21.5 ± 10.1 24.6 ± 11.1 ↑14.4% ns --     
Gender 3M:2F 9M:3F -- -- --     
  1. aDx, diagnosis; PMI, postmortem interval; MVA, motor vehicle accident; MR, mental retardation; ns, not significant.