Region of interest | % Total brain volume Mean ± Stdev | Diagnosis | Sex | Diagnosis * Sex | ||||
---|---|---|---|---|---|---|---|---|
ASD | TD | praw | pFDR | praw | pFDR | praw | pFDR | |
Caudate (L) | 2.13E−01 ± 3.24E−02 | 2.15E−01 ± 3.41E−02 | 0.525 | 0.664 | < 0.001 | ***< 0.001 | 0.427 | 0.558 |
Caudate (R) | 2.00E−01 ± 3.17E−02 | 2.03E−01 ± 3.32E−02 | 0.283 | 0.467 | < 0.001 | ***< 0.001 | 0.161 | 0.464 |
Putamen (L) | 3.55E−01 ± 5.31E−02 | 3.66E−01 ± 5.09E−02 | 0.042 | 0.277 | < 0.001 | ***< 0.001 | 0.020 | 0.238 |
Putamen (R) | 3.45E−01 ± 5.34E−02 | 3.55E−01 ± 5.14E−02 | 0.036 | 0.277 | < 0.001 | ***< 0.001 | 0.015 | 0.238 |
Nucleus accumbens (L) | 7.94E−02 ± 1.12E−02 | 8.10E−02 ± 1.08E−02 | 0.126 | 0.301 | < 0.001 | ***< 0.001 | 0.112 | 0.453 |
Nucleus accumbens (R) | 7.65E−02 ± 1.10E−02 | 7.89E−02 ± 1.12E−02 | 0.025 | 0.277 | < 0.001 | ***< 0.001 | 0.113 | 0.453 |
Globus pallidus external (L) | 6.49E−02 ± 1.03E−02 | 6.63E−02 ± 9.75E−03 | 0.208 | 0.411 | < 0.001 | ***< 0.001 | 0.017 | 0.238 |
Globus pallidus external (R) | 5.98E−02 ± 9.80E−03 | 6.13E−02 ± 8.91E−03 | 0.150 | 0.327 | < 0.001 | ***< 0.001 | 0.038 | 0.258 |
Globus pallidus internal (L) | 2.36E−02 ± 4.07E−03 | 2.40E−02 ± 3.85E−03 | 0.271 | 0.465 | < 0.001 | ***< 0.001 | 0.006 | 0.238 |
Globus pallidus internal (R) | 2.20E−02 ± 3.69E−03 | 2.32E−02 ± 3.92E−03 | 0.019 | 0.277 | < 0.001 | ***< 0.001 | 0.037 | 0.258 |
Subthalamic nucleus (L) | 5.24E−03 ± 9.61E−04 | 5.36E−03 ± 1.10E−03 | 0.419 | 0.609 | < 0.001 | ***< 0.001 | 0.139 | 0.464 |
Subthalamic nucleus (R) | 5.19E−03 ± 9.53E−04 | 5.16E−03 ± 1.00E−03 | 0.804 | 0.839 | < 0.001 | ***< 0.001 | 0.850 | 0.850 |
Substantia nigra (L) | 1.19E−02 ± 1.81E−03 | 1.22E−02 ± 2.03E−03 | 0.292 | 0.467 | 0.003 | **0.004 | 0.138 | 0.464 |
Substantia nigra (R) | 1.20E−02 ± 1.81E−03 | 1.24E−02 ± 2.05E−03 | 0.112 | 0.301 | < 0.001 | ***< 0.001 | 0.040 | 0.258 |
Lobule I−IV (L) | 2.80E−01 ± 4.96E−02 | 2.82E−01 ± 4.75E−02 | 0.547 | 0.673 | 0.029 | *0.031 | 0.381 | 0.558 |
Lobule I–IV (R) | 2.91E−01 ± 5.22E−02 | 2.95E−01 ± 4.60E−02 | 0.459 | 0.623 | 0.020 | *0.022 | 0.252 | 0.504 |
Lobule V (L) | 3.30E−01 ± 5.39E−02 | 3.40E−01 ± 5.16E−02 | 0.113 | 0.301 | < 0.001 | **0.001 | 0.390 | 0.558 |
Lobule V (R) | 3.37E−01 ± 5.82E−02 | 3.48E−01 ± 5.28E−02 | 0.105 | 0.301 | 0.006 | **0.008 | 0.432 | 0.558 |
Lobule VI (L) | 6.28E−01 ± 1.15E−01 | 6.60E−01 ± 8.94E−02 | 0.023 | 0.277 | 0.002 | **0.003 | 0.510 | 0.627 |
Lobule VI (vermis) | 1.51E−01 ± 3.19E−02 | 1.56E−01 ± 3.01E−02 | 0.230 | 0.425 | 0.002 | **0.002 | 0.228 | 0.504 |
Lobule VI (R) | 5.58E−01 ± 9.53E−02 | 5.86E−01 ± 9.04E−02 | 0.018 | 0.277 | < 0.001 | ***< 0.001 | 0.523 | 0.627 |
Crus I (L) | 1.02 ± 1.61E−01 | 1.05 ± 1.53E−01 | 0.069 | 0.277 | < 0.001 | ***< 0.001 | 0.832 | 0.850 |
Crus I (vermis) | 1.14E−03 ± 3.41E−04 | 1.16E−03 ± 3.55E−04 | 0.580 | 0.696 | < 0.001 | **0.001 | 0.113 | 0.453 |
Crus I (R) | 1.02 ± 1.44E−01 | 1.06 ± 1.50E−01 | 0.038 | 0.277 | < 0.001 | ***< 0.001 | 0.221 | 0.504 |
Crus II (L) | 7.64E−01 ± 1.15E−01 | 7.70E−01 ± 1.35E−01 | 0.408 | 0.609 | < 0.001 | ***< 0.001 | 0.292 | 0.540 |
Crus II (vermis) | 3.63E−02 ± 7.70E−03 | 3.80E−02 ± 7.77E−03 | 0.062 | 0.277 | < 0.001 | **0.001 | 0.365 | 0.558 |
Crus II (R) | 7.32E−01 ± 1.09E−01 | 7.49E−01 ± 1.23E−01 | 0.115 | 0.301 | < 0.001 | ***< 0.001 | 0.105 | 0.453 |
Lobule VIIb (L) | 3.57E−01 ± 5.39E−02 | 3.53E−01 ± 5.05E−02 | 0.859 | 0.877 | < 0.001 | ***< 0.001 | 0.164 | 0.464 |
Lobule VIIb (vermis) | 1.28E−02 ± 2.93E−03 | 1.34E−02 ± 2.66E−03 | 0.127 | 0.301 | 0.005 | **0.006 | 0.539 | 0.631 |
Lobule VIIb (R) | 3.81E−01 ± 5.49E−02 | 3.80E−01 ± 5.22E−02 | 0.740 | 0.790 | < 0.001 | ***< 0.001 | 0.043 | 0.258 |
Lobule VIIIa (L) | 3.95E−01 ± 6.30E−02 | 3.88E−01 ± 5.36E−02 | 0.660 | 0.773 | 0.001 | **0.002 | 0.200 | 0.504 |
Lobule VIIIa (vermis) | 8.75E−02 ± 1.55E−02 | 8.92E−02 ± 1.68E−02 | 0.414 | 0.609 | 0.007 | **0.009 | 0.331 | 0.558 |
Lobule VIIIa (R) | 3.53E−01 ± 5.34E−02 | 3.48E−01 ± 4.67E−02 | 0.712 | 0.778 | 0.009 | *0.010 | 0.234 | 0.504 |
Lobule VIIIb (L) | 3.42E−01 ± 5.20E−02 | 3.40E−01 ± 4.61E−02 | 0.999 | 0.999 | 0.049 | *0.050 | 0.842 | 0.850 |
Lobule VIIIb (vermis) | 4.29E−02 ± 7.65E−03 | 4.44E−02 ± 8.73E−03 | 0.112 | 0.301 | 0.001 | **0.002 | 0.397 | 0.558 |
Lobule VIIIb (R) | 3.34E−01 ± 5.50E−02 | 3.29E−01 ± 4.57E−02 | 0.714 | 0.778 | 0.221 | 0.221 | 0.820 | 0.850 |
Lobule IX (L) | 2.59E−01 ± 4.33E−02 | 2.61E−01 ± 4.82E−02 | 0.701 | 0.778 | 0.015 | *0.018 | 0.389 | 0.558 |
Lobule IX (vermis) | 5.66E−02 ± 9.18E−03 | 5.81E−02 ± 9.38E−03 | 0.214 | 0.411 | 0.004 | **0.006 | 0.164 | 0.464 |
Lobule IX (R) | 2.59E−01 ± 4.30E−02 | 2.63E−01 ± 4.68E−02 | 0.451 | 0.623 | 0.032 | *0.033 | 0.418 | 0.558 |
Lobule X (L) | 6.37E−02 ± 1.09E−02 | 6.63E−02 ± 9.48E−03 | 0.059 | 0.277 | < 0.001 | **0.001 | 0.572 | 0.638 |
Lobule X (vermis) | 2.71E−02 ± 5.09E−03 | 2.76E−02 ± 5.07E−03 | 0.494 | 0.641 | 0.009 | *0.010 | 0.559 | 0.638 |
Lobule X (R) | 5.37E−02 ± 9.79E−03 | 5.49E−02 ± 8.64E−03 | 0.261 | 0.463 | < 0.001 | ***< 0.001 | 0.442 | 0.558 |
Dentate nucleus (L) | 9.67E−02 ± 1.63E−02 | 1.00E−01 ± 1.53E−02 | 0.067 | 0.277 | < 0.001 | ***< 0.001 | 0.337 | 0.558 |
Dentate nucleus (R) | 1.06E−01 ± 1.84E−02 | 1.10E−01 ± 1.67E−02 | 0.113 | 0.301 | < 0.001 | ***< 0.001 | 0.253 | 0.504 |
Interposed nucleus (L) | 1.19E−02 ± 2.26E−03 | 1.22E−02 ± 1.97E−03 | 0.210 | 0.411 | < 0.001 | ***< 0.001 | 0.323 | 0.558 |
Interposed nucleus (R) | 1.23E−02 ± 2.39E−03 | 1.28E−02 ± 2.43E−03 | 0.132 | 0.301 | < 0.001 | ***< 0.001 | 0.178 | 0.476 |
Fastigial nucleus (L) | 4.05E−03 ± 8.35E−04 | 4.13E−03 ± 8.28E−04 | 0.467 | 0.623 | 0.028 | *0.031 | 0.700 | 0.763 |
Fastigial nucleus (R) | 3.20E−03 ± 6.86E−04 | 3.37E−03 ± 7.15E−04 | 0.047 | 0.277 | < 0.001 | ***< 0.001 | 0.262 | 0.504 |