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Table 1 Demographics and clinical characteristics of the participants

From: Developmental prediction modeling based on diffusion tensor imaging uncovering age-dependent heterogeneity in early childhood autistic brain

 

Discovery cohort

 
 

Autism

TDC

 
 

N

Mean ± SD

Range

N

Mean ± SD

Range

p value

Age (year)

68

5.46 ± 0.71

4.15–6.75

54

5.65 ± 0.67

4.25–6.70

0.13a

Sex

47 M/21F

–

–

33 M/21F

–

–

0.36b

Handedness

59R/3L/6 M

–

–

48R/1L/6 M

–

–

0.68b

Weight (kg)

68

19.90 ± 4.00

14–36

54

20.10 ± 3.50

14–31

0.51a

Height (cm)

68

111.95 ± 7.38

98–130

54

116.31 ± 7.57

95–131

0.0025a

Head motion (mm)

68

0.24 ± 0.05

0.16–0.40

54

0.35 ± 0.12

0.19–0.69

 < 0.001a

Age of mother (year)

47

34.49 ± 5.84

25.70–53.06

36

35.28 ± 4.97

24.67–48.19

0.22a

ADOS total

60

18.40 ± 4.0

9–28

–

–

–

–

 

Replication cohort

 
 

Autism

TDC

 
 

N

Mean ± SD

Range

N

Mean ± SD

Range

p value

Age (year)

23

5.13 ± 0.70

4.01–6.62

46

5.46 ± 0.80

4.04–6.88

0.13c

Sex

20 M/3F

–

–

39 M/7F

–

–

0.81b

Handedness

19R/4L

–

–

38R/8L

–

–

1 b

Head motion (mm)

23

0.10 ± 0.03

0.06–0.16

46

0.12 ± 0.09

0.06–0.54

0.30a

ADOS total

20

16.25 ± 5.4

7–26

–

–

 

–

  1. aWilcoxon rank sum test (two-sided). bχ2 test. cTwo-sample t-test
  2. TDC, typically developing children