Fig. 3

Foxp1-cKO mice display hyper-reactive to repeated whisker stimulation. A Schematic diagram of whisker nuisance task. The mouse behaviors in response to the whisker stimulation were scored using criteria described in the methods. B–D Quantification of the average time spent in freezing, guarding, and evasion behaviors of WT (n = 11) and Foxp1-cKO mice (n = 8). Circles represent the data points from each animal. ***p < 0.001. E–F Quantify the number of startle and climb events in response to stick during each session. Circles represent the data points from each animal. *p < 0.05, **p < 0.01, ***p < 0.001