Fig. 3
From: Exploratory analysis of L1 retrotransposons expression in autism
Upregulated L1 elements are expressed within introns of actively transcribed genes. A Histone marks aligned reads density profiles computed for all upregulated L1 elements and total annotated L1 elements for six major histone marks, the profile extends along the whole length of the L1 elements (~ 6 kbp) as well as along 5 kbp upstream and downstream with respect to each L1 element. B Genomic localization of all upregulated L1 elements in all samples. C Volcano plot representing differentially retained introns between controls and samples characterized by a strong L1 upregulation, significance lines: FDR = 0.05, |Log2(FoldChange)|= 1. D Percentage of reads shared among random exons and their closest upregulated L1, exons and their closest exon, random intronic 6 kbp regions and their closest exons